GPR83

GPR83
Identifiers
Aliases	GPR83, GIR, GPR72, G protein-coupled receptor 83
External IDs	OMIM: 605569; MGI: 95712; HomoloGene: 7732; GeneCards: GPR83; OMA:GPR83 - orthologs
Gene location (Human)
Chr.	Chromosome 11 (human)
End	94,401,419 bp
Gene location (Mouse)
Chr.	Chromosome 9 (mouse)
End	14,782,085 bp
RNA expression pattern
	Top expressed in
	cerebellar vermis; ; middle temporal gyrus; ; cerebellar hemisphere; ; right hemisphere of cerebellum; ; Brodmann area 23; ; testicle; ; superior frontal gyrus; ; spinal ganglia; ; prefrontal cortex; ; entorhinal cortex;
	Top expressed in
	olfactory tubercle; ; nucleus accumbens; ; pectoral muscles; ; pectoralis minor muscle; ; pectoralis major; ; mammillary body; ; lobe of prostate; ; globus pallidus; ; superior frontal gyrus; ; lumbar subsegment of spinal cord;
	More reference expression data
	n/a
Gene ontology
Molecular function	neuropeptide Y receptor activity; G protein-coupled receptor activity; signal transducer activity;
Cellular component	integral component of membrane; plasma membrane; membrane; non-motile cilium; cilium;
Biological process	response to glucocorticoid; neuropeptide signaling pathway; signal transduction; G protein-coupled receptor signaling pathway;
	Sources:Amigo / QuickGO
Orthologs
	10888
	14608
	ENSG00000123901
	ENSMUSG00000031932
	Q9NYM4
	P30731
	NM_016540; NM_001330345
	NM_010287; NM_001310734
	NP_001317274; NP_057624
	NP_001297663; NP_034417
	Wikidata
View/Edit Human	View/Edit Mouse

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Probable G-protein coupled receptor 83 is a protein that in humans is encoded by the GPR83 gene.^[5]^[6]^[7]

References

^ ^a ^b ^c GRCh38: Ensembl release 89: ENSG00000123901 – Ensembl, May 2017
^ ^a ^b ^c GRCm38: Ensembl release 89: ENSMUSG00000031932 – Ensembl, May 2017
^ "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
^ "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
^ Parker R, Liu M, Eyre HJ, Copeland NG, Gilbert DJ, Crawford J, Sutherland GR, Jenkins NA, Herzog H (Jul 2000). "Y-receptor-like genes GPR72 and GPR73: molecular cloning, genomic organisation and assignment to human chromosome 11q21.1 and 2p14 and mouse chromosome 9 and 6". Biochim Biophys Acta. 1491 (1–3): 369–75. doi:10.1016/s0167-4781(00)00023-3. PMID 10760605.
^ De Moerlooze L, Williamson J, Liners F, Perret J, Parmentier M (Nov 2000). "Cloning and chromosomal mapping of the mouse and human genes encoding the orphan glucocorticoid-induced receptor (GPR83)". Cytogenet Cell Genet. 90 (1–2): 146–50. doi:10.1159/000015650. PMID 11060465. S2CID 8439947.
^ "Entrez Gene: GPR83 G protein-coupled receptor 83".

Nagase T, Kikuno R, Ishikawa K, et al. (2000). "Prediction of the coding sequences of unidentified human genes. XVII. The complete sequences of 100 new cDNA clones from brain which code for large proteins in vitro". DNA Res. 7 (2): 143–50. doi:10.1093/dnares/7.2.143. PMID 10819331.
Strausberg RL, Feingold EA, Grouse LH, et al. (2003). "Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences". Proc. Natl. Acad. Sci. U.S.A. 99 (26): 16899–903. Bibcode:2002PNAS...9916899M. doi:10.1073/pnas.242603899. PMC 139241. PMID 12477932.
Hansen W, Loser K, Westendorf AM, et al. (2006). "G protein-coupled receptor 83 overexpression in naive CD4+CD25- T cells leads to the induction of Foxp3+ regulatory T cells in vivo". J. Immunol. 177 (1): 209–15. doi:10.4049/jimmunol.177.1.209. PMID 16785516.

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[refGRCh38Ensembl-1] GRCh38: Ensembl release 89: ENSG00000123901 – Ensembl, May 2017

[refGRCm38Ensembl-2] GRCm38: Ensembl release 89: ENSMUSG00000031932 – Ensembl, May 2017

[3] "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.

[4] "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.

[pmid10760605-5] Parker R, Liu M, Eyre HJ, Copeland NG, Gilbert DJ, Crawford J, Sutherland GR, Jenkins NA, Herzog H (Jul 2000). "Y-receptor-like genes GPR72 and GPR73: molecular cloning, genomic organisation and assignment to human chromosome 11q21.1 and 2p14 and mouse chromosome 9 and 6". Biochim Biophys Acta. 1491 (1–3): 369–75. doi:10.1016/s0167-4781(00)00023-3. PMID 10760605.

[pmid11060465-6] De Moerlooze L, Williamson J, Liners F, Perret J, Parmentier M (Nov 2000). "Cloning and chromosomal mapping of the mouse and human genes encoding the orphan glucocorticoid-induced receptor (GPR83)". Cytogenet Cell Genet. 90 (1–2): 146–50. doi:10.1159/000015650. PMID 11060465. S2CID 8439947.

[entrez-7] "Entrez Gene: GPR83 G protein-coupled receptor 83".

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References

Further reading