GPRC6A: Difference between revisions
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'''G-protein coupled receptor family C group 6 member A''' is a [[protein]] that in humans is encoded by the ''GPRC6A'' [[gene]].<ref name="entrez">{{cite web | title = Entrez Gene: GPRC6A G protein-coupled receptor, family C, group 6, member A| url = http://www.ncbi.nlm.nih.gov/sites/entrez?Db=gene&Cmd=ShowDetailView&TermToSearch=222545| accessdate = }}</ref> This receptor functions as a sensor of L-[[amino acid]]s.<ref name="pmid15576628">{{cite journal | author = Wellendorph P, Hansen KB, Balsgaard A, Greenwood JR, Egebjerg J, Bräuner-Osborne H | title = Deorphanization of GPRC6A: a promiscuous L-alpha-amino acid receptor with preference for basic amino acids | journal = Mol. Pharmacol. | volume = 67 | issue = 3 | pages = 589–97 | year = 2005 | pmid = 15576628 | doi = 10.1124/mol.104.007559 }}</ref> |
'''G-protein coupled receptor family C group 6 member A''' is a [[protein]] that in humans is encoded by the ''GPRC6A'' [[gene]].<ref name="entrez">{{cite web | title = Entrez Gene: GPRC6A G protein-coupled receptor, family C, group 6, member A| url = http://www.ncbi.nlm.nih.gov/sites/entrez?Db=gene&Cmd=ShowDetailView&TermToSearch=222545| accessdate = }}</ref> This receptor functions as a sensor of L-[[amino acid]]s.<ref name="pmid15576628">{{cite journal | author = Wellendorph P, Hansen KB, Balsgaard A, Greenwood JR, Egebjerg J, Bräuner-Osborne H | title = Deorphanization of GPRC6A: a promiscuous L-alpha-amino acid receptor with preference for basic amino acids | journal = Mol. Pharmacol. | volume = 67 | issue = 3 | pages = 589–97 | year = 2005 | pmid = 15576628 | doi = 10.1124/mol.104.007559 }}</ref> GPRC6A has also been linked to prostate cancer progression, and it has mediated rapid, non-genomic prostate cancer cell responses to [[testosterone]] and other [[steroids]]<ref>{{cite journal|last=Pi|first=Min|coauthors=Darryl Quarles|title=GPRC6ARegulates Prostate Cancer Progression|journal=Prostate|year=2011|volume=ASAP Publication|doi=10.1002/pros.21442|url=http://dx.doi.org/10.1002/pros.21442|accessdate=29 June 2011}}</ref> . |
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Revision as of 19:25, 29 June 2011
Template:PBB G-protein coupled receptor family C group 6 member A is a protein that in humans is encoded by the GPRC6A gene.[1] This receptor functions as a sensor of L-amino acids.[2] GPRC6A has also been linked to prostate cancer progression, and it has mediated rapid, non-genomic prostate cancer cell responses to testosterone and other steroids[3] .
References
- ^ "Entrez Gene: GPRC6A G protein-coupled receptor, family C, group 6, member A".
- ^ Wellendorph P, Hansen KB, Balsgaard A, Greenwood JR, Egebjerg J, Bräuner-Osborne H (2005). "Deorphanization of GPRC6A: a promiscuous L-alpha-amino acid receptor with preference for basic amino acids". Mol. Pharmacol. 67 (3): 589–97. doi:10.1124/mol.104.007559. PMID 15576628.
{{cite journal}}: CS1 maint: multiple names: authors list (link) - ^ Pi, Min (2011). "GPRC6ARegulates Prostate Cancer Progression". Prostate. ASAP Publication. doi:10.1002/pros.21442. Retrieved 29 June 2011.
{{cite journal}}: Unknown parameter|coauthors=ignored (|author=suggested) (help)
Further reading
External links
- "Calcium-Sensing Receptors: GPRC6". IUPHAR Database of Receptors and Ion Channels. International Union of Basic and Clinical Pharmacology.
{{cite web}}: Cite has empty unknown parameter:|coauthors=(help) - GPRC6A+protein,+human at the U.S. National Library of Medicine Medical Subject Headings (MeSH)
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