Eltoprazine: Difference between revisions
Content deleted Content added
No edit summary |
RjwilmsiBot (talk | contribs) m fixing page range dashes using Project:AWB |
||
| Line 20: | Line 20: | ||
}} |
}} |
||
'''Eltoprazine''' ('''DU-28,853''') is a [[psychoactive drug]] and [[research chemical]] of the [[piperazine]] [[chemical class]]. It is a so-called ''[[serenic]]'' or antiaggressive agent.<ref name="pmid2091890">{{cite journal | author = Olivier B, Mos J, Rasmussen D. | title = Behavioural pharmacology of the serenic, eltoprazine | journal = Drug Metabol Drug Interact. | volume = 8 | issue = 1-2 | pages = |
'''Eltoprazine''' ('''DU-28,853''') is a [[psychoactive drug]] and [[research chemical]] of the [[piperazine]] [[chemical class]]. It is a so-called ''[[serenic]]'' or antiaggressive agent.<ref name="pmid2091890">{{cite journal | author = Olivier B, Mos J, Rasmussen D. | title = Behavioural pharmacology of the serenic, eltoprazine | journal = Drug Metabol Drug Interact. | volume = 8 | issue = 1-2 | pages = 31–83 | year = 1990 | pmid = 2091890 }}</ref> It is closely related to several other piperazines, including [[fluprazine]], [[batoprazine]], [[DU-28,412]], [[flesinoxan]], and [[TFMPP]], as well as more distantly to the [[azapirone]]s such as [[buspirone]]. Eltoprazine acts as an [[agonist]] at the [[5-HT1A|5-HT<sub>1A</sub>]] and [[5-HT1B|5-HT<sub>1B</sub>]] receptors, and as an [[antagonist]] at the [[5-HT2C|5-HT<sub>2C</sub>]] receptor.<ref name="pmid1982626">{{cite journal | author = Schipper J, Tulp MT, Sijbesma H. | title = Neurochemical profile of eltoprazine. | journal = Drug Metabol Drug Interact. | volume = 8 | issue = 1-2 | pages = 85–114 | year = 1990 | pmid = 1982626 }}</ref> |
||
{{pharmacology-stub}} |
{{pharmacology-stub}} |
||
Revision as of 10:27, 18 December 2009
 | |
| Clinical data | |
|---|---|
| ATC code |
|
| Identifiers | |
| |
| CAS Number | |
| PubChem CID | |
| CompTox Dashboard (EPA) | |
| Chemical and physical data | |
| Formula | C12H16N2O2 |
| Molar mass | 220.121 g/mol g·mol−1 |
| 3D model (JSmol) | |
| |
Eltoprazine (DU-28,853) is a psychoactive drug and research chemical of the piperazine chemical class. It is a so-called serenic or antiaggressive agent.[1] It is closely related to several other piperazines, including fluprazine, batoprazine, DU-28,412, flesinoxan, and TFMPP, as well as more distantly to the azapirones such as buspirone. Eltoprazine acts as an agonist at the 5-HT1A and 5-HT1B receptors, and as an antagonist at the 5-HT2C receptor.[2]
 | This pharmacology-related article is a stub. You can help Wikipedia by expanding it. |
See also
References
- ^ Olivier B, Mos J, Rasmussen D. (1990). "Behavioural pharmacology of the serenic, eltoprazine". Drug Metabol Drug Interact. 8 (1–2): 31–83. PMID 2091890.
{{cite journal}}: CS1 maint: multiple names: authors list (link) - ^ Schipper J, Tulp MT, Sijbesma H. (1990). "Neurochemical profile of eltoprazine". Drug Metabol Drug Interact. 8 (1–2): 85–114. PMID 1982626.
{{cite journal}}: CS1 maint: multiple names: authors list (link)