GPR19: Difference between revisions

GPR19
Identifiers
Aliases	GPR19, G protein-coupled receptor 19
External IDs	OMIM: 602927; MGI: 892973; HomoloGene: 4476; GeneCards: GPR19; OMA:GPR19 - orthologs
Gene location (Human)
Chr.	Chromosome 12 (human)
End	12,696,207 bp
Gene location (Mouse)
Chr.	Chromosome 6 (mouse)
End	134,875,541 bp
RNA expression pattern
	Top expressed in
	testicle; ; gonad; ; Brodmann area 23; ; endothelial cell; ; middle temporal gyrus; ; primary visual cortex; ; ganglionic eminence; ; cerebellar hemisphere; ; pituitary gland; ; right hemisphere of cerebellum;
	Top expressed in
	spermatocyte; ; medial ganglionic eminence; ; spermatid; ; Rostral migratory stream; ; humerus; ; seminiferous tubule; ; zygote; ; pituitary gland; ; fibula; ; suprachiasmatic nucleus;
	More reference expression data
	More reference expression data
Gene ontology
Molecular function	signal transducer activity; G protein-coupled receptor activity;
Cellular component	integral component of plasma membrane; membrane; integral component of membrane; plasma membrane; cilium;
Biological process	signal transduction; G protein-coupled receptor signaling pathway; neuropeptide signaling pathway; chemical synaptic transmission; feeding behavior;
	Sources:Amigo / QuickGO
Orthologs
	2842
	14760
	ENSG00000183150
	ENSMUSG00000032641
	Q15760
	Q61121
	NM_006143
NM_001167693; NM_001167694; NM_001167695; NM_001167696; NM_001167697;
	NM_001167699; NM_001167700; NM_008157; NM_001362048; NM_001362049; NM_001362050; NM_001362051; NM_001362052
	NP_006134
NP_001161166; NP_001161167; NP_001161168; NP_001161169; NP_001161171;
	NP_001161172; NP_032183; NP_001348977; NP_001348978; NP_001348979; NP_001348980; NP_001348981
	Wikidata
View/Edit Human	View/Edit Mouse

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Latest revision as of 05:38, 24 August 2024

Probable G-protein coupled receptor 19 is a protein that in humans is encoded by the GPR19 gene.^[5] GPR19 has been proposed as the receptor for the peptide hormone adropin.^[6]

References

^ ^a ^b ^c GRCh38: Ensembl release 89: ENSG00000183150 – Ensembl, May 2017
^ ^a ^b ^c GRCm38: Ensembl release 89: ENSMUSG00000032641 – Ensembl, May 2017
^ "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
^ "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
^ "Entrez Gene: GPR19 G protein-coupled receptor 19".
^ Stein LM, Yosten GL, Samson WK (March 2016). "Adropin acts in brain to inhibit water drinking: potential interaction with the orphan G protein-coupled receptor, GPR19". American Journal of Physiology. Regulatory, Integrative and Comparative Physiology. 310 (6): R476–R480. doi:10.1152/ajpregu.00511.2015. PMC 4867374. PMID 26739651.

O'Dowd BF, Nguyen T, Lynch KR, Kolakowski LF, Thompson M, Cheng R, et al. (October 1996). "A novel gene codes for a putative G protein-coupled receptor with an abundant expression in brain". FEBS Letters. 394 (3): 325–329. doi:10.1016/0014-5793(96)00901-5. PMID 8830667. S2CID 1484916.
Montpetit A, Sinnett D (1999). "Physical mapping of the G-protein coupled receptor 19 (GPR19) in the chromosome 12p12.3 region frequently rearranged in cancer cells". Human Genetics. 105 (1–2): 162–164. doi:10.1007/s004390051080. PMID 10480372.
Otsuki T, Ota T, Nishikawa T, Hayashi K, Suzuki Y, Yamamoto J, et al. (2007). "Signal sequence and keyword trap in silico for selection of full-length human cDNAs encoding secretion or membrane proteins from oligo-capped cDNA libraries". DNA Research. 12 (2): 117–126. doi:10.1093/dnares/12.2.117. PMID 16303743.

This transmembrane receptor-related article is a stub. You can help Wikipedia by expanding it.

[refGRCh38Ensembl-1] GRCh38: Ensembl release 89: ENSG00000183150 – Ensembl, May 2017

[refGRCm38Ensembl-2] GRCm38: Ensembl release 89: ENSMUSG00000032641 – Ensembl, May 2017

[3] "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.

[4] "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.

[entrez-5] "Entrez Gene: GPR19 G protein-coupled receptor 19".

[6] Stein LM, Yosten GL, Samson WK (March 2016). "Adropin acts in brain to inhibit water drinking: potential interaction with the orphan G protein-coupled receptor, GPR19". American Journal of Physiology. Regulatory, Integrative and Comparative Physiology. 310 (6): R476–R480. doi:10.1152/ajpregu.00511.2015. PMC 4867374. PMID 26739651.

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@@ Line 1: / Line 1: @@
+{{Short description|Protein-coding gene in the species Homo sapiens}}
+{{cs1 config|name-list-style=vanc|display-authors=6}}
 {{Infobox_gene}}
-'''Probable [[G protein|G-protein]] coupled receptor 19''' is a [[protein]] that in humans is encoded by the ''GPR19'' [[gene]].<ref name="entrez">{{cite web | title = Entrez Gene: GPR19 G protein-coupled receptor 19| url = https://www.ncbi.nlm.nih.gov/sites/entrez?Db=gene&Cmd=ShowDetailView&TermToSearch=2842| accessdate = }}</ref>
+'''Probable [[G protein|G-protein]] coupled receptor 19''' is a [[protein]] that in humans is encoded by the ''GPR19'' [[gene]].<ref name="entrez">{{cite web | title = Entrez Gene: GPR19 G protein-coupled receptor 19| url = https://www.ncbi.nlm.nih.gov/sites/entrez?Db=gene&Cmd=ShowDetailView&TermToSearch=2842}}</ref> GPR19 has been proposed as the [[Receptor (biochemistry)|receptor]] for the [[peptide hormone]] [[adropin]].<ref>{{cite journal | vauthors = Stein LM, Yosten GL, Samson WK | title = Adropin acts in brain to inhibit water drinking: potential interaction with the orphan G protein-coupled receptor, GPR19 | journal = American Journal of Physiology. Regulatory, Integrative and Comparative Physiology | volume = 310 | issue = 6 | pages = R476-R480 | date = March 2016 | pmid = 26739651 | pmc = 4867374 | doi = 10.1152/ajpregu.00511.2015 }}</ref>
-<!-- The PBB_Summary template is automatically maintained by Protein Box Bot.  See Template:PBB_Controls to Stop updates. -->
-{{PBB_Summary
-| section_title =
-| summary_text =
-}}
-==References==
+== References ==
 {{reflist}}
-==Further reading==
+== Further reading ==
-{{refbegin | 2}}
+{{refbegin}}
+* {{cite journal | vauthors = O'Dowd BF, Nguyen T, Lynch KR, Kolakowski LF, Thompson M, Cheng R, Marchese A, Ng G, Heng HH, George SR | title = A novel gene codes for a putative G protein-coupled receptor with an abundant expression in brain | journal = FEBS Letters | volume = 394 | issue = 3 | pages = 325–329 | date = October 1996 | pmid = 8830667 | doi = 10.1016/0014-5793(96)00901-5 | s2cid = 1484916 | doi-access = free }}
-{{PBB_Further_reading
+* {{cite journal | vauthors = Montpetit A, Sinnett D | title = Physical mapping of the G-protein coupled receptor 19 (GPR19) in the chromosome 12p12.3 region frequently rearranged in cancer cells | journal = Human Genetics | volume = 105 | issue = 1-2 | pages = 162–164 | year = 1999 | pmid = 10480372 | doi = 10.1007/s004390051080 }}
-| citations =
+* {{cite journal | vauthors = Otsuki T, Ota T, Nishikawa T, Hayashi K, Suzuki Y, Yamamoto J, Wakamatsu A, Kimura K, Sakamoto K, Hatano N, Kawai Y, Ishii S, Saito K, Kojima S, Sugiyama T, Ono T, Okano K, Yoshikawa Y, Aotsuka S, Sasaki N, Hattori A, Okumura K, Nagai K, Sugano S, Isogai T | title = Signal sequence and keyword trap in silico for selection of full-length human cDNAs encoding secretion or membrane proteins from oligo-capped cDNA libraries | journal = DNA Research | volume = 12 | issue = 2 | pages = 117–126 | year = 2007 | pmid = 16303743 | doi = 10.1093/dnares/12.2.117 | doi-access = free }}
-*{{cite journal   |vauthors=O'Dowd BF, Nguyen T, Lynch KR, etal |title=A novel gene codes for a putative G protein-coupled receptor with an abundant expression in brain. |journal=FEBS Lett. |volume=394 |issue= 3 |pages= 325–9 |year= 1996 |pmid= 8830667 |doi=10.1016/0014-5793(96)00901-5  }}
-*{{cite journal  | vauthors=Montpetit A, Sinnett D |title=Physical mapping of the G-protein coupled receptor 19 (GPR19) in the chromosome 12p12.3 region frequently rearranged in cancer cells. |journal=Hum. Genet. |volume=105 |issue= 1–2 |pages= 162–4 |year= 1999 |pmid= 10480372 |doi=10.1007/s004390051080  }}
-*{{cite journal   |vauthors=Otsuki T, Ota T, Nishikawa T, etal |title=Signal sequence and keyword trap in silico for selection of full-length human cDNAs encoding secretion or membrane proteins from oligo-capped cDNA libraries |journal=DNA Res. |volume=12 |issue= 2 |pages= 117–26 |year= 2007 |pmid= 16303743 |doi= 10.1093/dnares/12.2.117 }}
-}}
 {{refend}}
@@ Line 23: / Line 17: @@
 [[Category:G protein-coupled receptors]]
 {{transmembranereceptor-stub}}