Atizoram: Difference between revisions
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| ImageFile = Atizoram structure.svg |
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| IUPACName = 5-<nowiki/>{3-[(1''S'',2''S'',4''R'')-Bicyclo[2.2.1]hept-2-yloxy]-4-methoxyphenyl}tetrahydro-2(1''H'')-pyrimidinone |
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| OtherNames = CP-80633 |
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| CASNo = 135637-46-6 |
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| UNII = O84FJB49WI |
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| ChEMBL = 1229569 |
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| SMILES = COC1=C(C=C(C=C1)C2CNC(=O)NC2)O[C@H]3C[C@@H]4CC[C@H]3C4 |
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| StdInChI = 1S/C18H24N2O3/c1-22-15-5-4-12(14-9-19-18(21)20-10-14)8-17(15)23-16-7-11-2-3-13(16)6-11/h4-5,8,11,13-14,16H,2-3,6-7,9-10H2,1H3,(H2,19,20,21)/t11-,13+,16+/m1/s1 |
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| StdInChIKey = LITNEAPWQHVPOK-FFSVYQOJSA-N |
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| C=18 | H=24 | N=2 | O=3 |
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'''Atizoram''' ('''CP-80633''') is a [[Phosphodiesterase-4 inhibitor|phosphodiesterase 4 inhibitor]].<ref>{{cite journal | pmid= 9360015 | title = Differential in vivo and in vitro bronchorelaxant activities of CP-80,633, a selective phosphodiesterase 4 inhibitor | volume=75 | issue=8 | date=August 1997 | journal=Can. J. Physiol. Pharmacol. | pages=1001–8| last1 = Wright | first1 = K. F. | last2 = Turner | first2 = C. R. | last3 = Jayasinghe-Beck | first3 = R. | last4 = Cohen | first4 = V. L. | last5 = Cheng | first5 = J. B. | last6 = Watson | first6 = J. W. | doi = 10.1139/y97-123 }}</ref> |
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CP-80633 is a [[phosphodiesterase inhibitor]]. |
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==References== |
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{{reflist}} |
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{{Phosphodiesterase inhibitors}} |
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==External links== |
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[http://www.ncbi.nlm.nih.gov/pubmed/9360015 Differential in vivo and in vitro bronchorelaxant activities of CP-80,633, a selective phosphodiesterase 4 inhibitor] |
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[[Category:PDE4 inhibitors]] |
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Latest revision as of 20:22, 4 November 2023
Names | |
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IUPAC name
5-{3-[(1S,2S,4R)-Bicyclo[2.2.1]hept-2-yloxy]-4-methoxyphenyl}tetrahydro-2(1H)-pyrimidinone
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Other names
CP-80633
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Identifiers | |
3D model (JSmol)
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ChEMBL | |
ChemSpider | |
PubChem CID
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UNII | |
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Properties | |
C18H24N2O3 | |
Molar mass | 316.401 g·mol−1 |
Except where otherwise noted, data are given for materials in their standard state (at 25 °C [77 °F], 100 kPa).
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Atizoram (CP-80633) is a phosphodiesterase 4 inhibitor.[1]
References
[edit]- ^ Wright, K. F.; Turner, C. R.; Jayasinghe-Beck, R.; Cohen, V. L.; Cheng, J. B.; Watson, J. W. (August 1997). "Differential in vivo and in vitro bronchorelaxant activities of CP-80,633, a selective phosphodiesterase 4 inhibitor". Can. J. Physiol. Pharmacol. 75 (8): 1001–8. doi:10.1139/y97-123. PMID 9360015.