TAS2R60: Difference between revisions

TAS2R60
Identifiers
Aliases	TAS2R60, T2R56, T2R60, taste 2 receptor member 60
External IDs	OMIM: 613968; MGI: 2681302; HomoloGene: 52230; GeneCards: TAS2R60; OMA:TAS2R60 - orthologs
Gene location (Human)
Chr.	Chromosome 7 (human)
End	143,444,409 bp
Gene location (Mouse)
Chr.	Chromosome 6 (mouse)
End	42,383,460 bp
RNA expression pattern
	Top expressed in
	gonad; ; mucosa of large intestine; ; mucosa of transverse colon; ; blood; ; cell; ; white blood cell; ; monocyte; ; appendix; ; liver; ; placenta;
	Top expressed in
	embryo; ; granulocyte; ; cerebellar cortex;
	More reference expression data
	n/a
Gene ontology
Molecular function	G protein-coupled receptor activity; signal transducer activity; bitter taste receptor activity;
Cellular component	integral component of membrane; plasma membrane; membrane;
Biological process	sensory perception of bitter taste; detection of chemical stimulus involved in sensory perception of bitter taste; signal transduction; response to stimulus; sensory perception of taste; G protein-coupled receptor signaling pathway;
	Sources:Amigo / QuickGO
Orthologs
	338398
	387512
	ENSG00000185899; ENSG00000285341
	ENSMUSG00000056203
	P59551
	Q7TQA9
	NM_177437
	NM_199159
	NP_803186
	NP_954610
	Wikidata
View/Edit Human	View/Edit Mouse

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Latest revision as of 04:02, 22 June 2022

Taste receptor type 2 member 60 is a protein that in humans is encoded by the TAS2R60 gene.^[5]^[6]

References

^ ^a ^b ^c ENSG00000285341 GRCh38: Ensembl release 89: ENSG00000185899, ENSG00000285341 – Ensembl, May 2017
^ ^a ^b ^c GRCm38: Ensembl release 89: ENSMUSG00000056203 – Ensembl, May 2017
^ "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
^ "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
^ Conte C, Ebeling M, Marcuz A, Nef P, Andres-Barquin PJ (Feb 2003). "Identification and characterization of human taste receptor genes belonging to the TAS2R family". Cytogenet Genome Res. 98 (1): 45–53. doi:10.1159/000068546. PMID 12584440. S2CID 1542970.
^ "Entrez Gene: TAS2R60 taste receptor, type 2, member 60".

Margolskee RF (2002). "Molecular mechanisms of bitter and sweet taste transduction". J. Biol. Chem. 277 (1): 1–4. doi:10.1074/jbc.R100054200. PMID 11696554.
Montmayeur JP, Matsunami H (2002). "Receptors for bitter and sweet taste". Curr. Opin. Neurobiol. 12 (4): 366–71. doi:10.1016/S0959-4388(02)00345-8. PMID 12139982. S2CID 37807140.
Zhang Y, Hoon MA, Chandrashekar J, Mueller KL, Cook B, Wu D, Zuker CS, Ryba NJ (2003). "Coding of sweet, bitter, and umami tastes: different receptor cells sharing similar signaling pathways". Cell. 112 (3): 293–301. doi:10.1016/S0092-8674(03)00071-0. PMID 12581520. S2CID 718601.
Shi P, Zhang J, Yang H, Zhang YP (2004). "Adaptive diversification of bitter taste receptor genes in Mammalian evolution". Mol. Biol. Evol. 20 (5): 805–14. doi:10.1093/molbev/msg083. PMID 12679530.
Fischer A, Gilad Y, Man O, Pääbo S (2005). "Evolution of bitter taste receptors in humans and apes". Mol. Biol. Evol. 22 (3): 432–6. doi:10.1093/molbev/msi027. PMID 15496549.
Go Y, Satta Y, Takenaka O, Takahata N (2006). "Lineage-Specific Loss of Function of Bitter Taste Receptor Genes in Humans and Nonhuman Primates". Genetics. 170 (1): 313–26. doi:10.1534/genetics.104.037523. PMC 1449719. PMID 15744053.

This article incorporates text from the United States National Library of Medicine, which is in the public domain.

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[refGRCh38Ensembl-1] ENSG00000285341 GRCh38: Ensembl release 89: ENSG00000185899, ENSG00000285341 – Ensembl, May 2017

[refGRCm38Ensembl-2] GRCm38: Ensembl release 89: ENSMUSG00000056203 – Ensembl, May 2017

[3] "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.

[4] "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.

[pmid12584440-5] Conte C, Ebeling M, Marcuz A, Nef P, Andres-Barquin PJ (Feb 2003). "Identification and characterization of human taste receptor genes belonging to the TAS2R family". Cytogenet Genome Res. 98 (1): 45–53. doi:10.1159/000068546. PMID 12584440. S2CID 1542970.

[entrez-6] "Entrez Gene: TAS2R60 taste receptor, type 2, member 60".

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@@ Line 1: / Line 1: @@
+{{Short description|Protein-coding gene in the species Homo sapiens}}
-{{Orphan|date=February 2009}}
+{{Infobox_gene}}
-{{PBB|geneid=338398}}
-'''Taste receptor, type 2, member 60''', also known as '''TAS2R60''', is a human [[gene]].<ref name="entrez">{{cite web | title = Entrez Gene: TAS2R60 taste receptor, type 2, member 60| url = http://www.ncbi.nlm.nih.gov/sites/entrez?Db=gene&Cmd=ShowDetailView&TermToSearch=338398| accessdate = }}</ref>
+'''Taste receptor type 2 member 60''' is a [[protein]] that in humans is encoded by the ''TAS2R60'' [[gene]].<ref name="pmid12584440">{{cite journal | vauthors = Conte C, Ebeling M, Marcuz A, Nef P, Andres-Barquin PJ | title = Identification and characterization of human taste receptor genes belonging to the TAS2R family | journal = Cytogenet Genome Res | volume = 98 | issue = 1 | pages = 45–53 | date = Feb 2003 | pmid = 12584440 | doi = 10.1159/000068546 | s2cid = 1542970 }}</ref><ref name="entrez">{{cite web | title = Entrez Gene: TAS2R60 taste receptor, type 2, member 60| url = https://www.ncbi.nlm.nih.gov/sites/entrez?Db=gene&Cmd=ShowDetailView&TermToSearch=338398}}</ref>
-<!-- The PBB_Summary template is automatically maintained by Protein Box Bot.  See Template:PBB_Controls to Stop updates. -->
-{{PBB_Summary
-| section_title =
-| summary_text =
-}}
 ==See also==
@@ Line 17: / Line 11: @@
 ==Further reading==
 {{refbegin | 2}}
+*{{cite journal | author = Margolskee RF | title = Molecular mechanisms of bitter and sweet taste transduction. | journal = J. Biol. Chem. | volume = 277 | issue = 1 | pages = 1–4 | year = 2002 | pmid = 11696554 | doi = 10.1074/jbc.R100054200 | doi-access = free }}
-{{PBB_Further_reading
+*{{cite journal | vauthors = Montmayeur JP, Matsunami H | title = Receptors for bitter and sweet taste. | journal = Curr. Opin. Neurobiol. | volume = 12 | issue = 4 | pages = 366–71 | year = 2002 | pmid = 12139982 | doi = 10.1016/S0959-4388(02)00345-8 | s2cid = 37807140 }}
-| citations =
-*{{cite journal  | author=Margolskee RF |title=Molecular mechanisms of bitter and sweet taste transduction. |journal=J. Biol. Chem. |volume=277 |issue= 1 |pages= 1–4 |year= 2002 |pmid= 11696554 |doi= 10.1074/jbc.R100054200 }}
+*{{cite journal | vauthors = Zhang Y, Hoon MA, Chandrashekar J, Mueller KL, Cook B, Wu D, Zuker CS, Ryba NJ | title = Coding of sweet, bitter, and umami tastes: different receptor cells sharing similar signaling pathways | journal = Cell | volume = 112 | issue = 3 | pages = 293–301 | year = 2003 | pmid = 12581520 | doi = 10.1016/S0092-8674(03)00071-0 | s2cid = 718601 | doi-access = free }}
-*{{cite journal  | author=Montmayeur JP, Matsunami H |title=Receptors for bitter and sweet taste. |journal=Curr. Opin. Neurobiol. |volume=12 |issue= 4 |pages= 366–71 |year= 2002 |pmid= 12139982 |doi=  }}
+*{{cite journal | vauthors = Shi P, Zhang J, Yang H, Zhang YP | title = Adaptive diversification of bitter taste receptor genes in Mammalian evolution | journal = Mol. Biol. Evol. | volume = 20 | issue = 5 | pages = 805–14 | year = 2004 | pmid = 12679530 | doi = 10.1093/molbev/msg083 | doi-access = free }}
-*{{cite journal  | author=Strausberg RL, Feingold EA, Grouse LH, ''et al.'' |title=Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. |journal=Proc. Natl. Acad. Sci. U.S.A. |volume=99 |issue= 26 |pages= 16899–903 |year= 2003 |pmid= 12477932 |doi= 10.1073/pnas.242603899 }}
+*{{cite journal | vauthors = Fischer A, Gilad Y, Man O, Pääbo S | title = Evolution of bitter taste receptors in humans and apes | journal = Mol. Biol. Evol. | volume = 22 | issue = 3 | pages = 432–6 | year = 2005 | pmid = 15496549 | doi = 10.1093/molbev/msi027 | doi-access = free }}
-*{{cite journal  | author=Zhang Y, Hoon MA, Chandrashekar J, ''et al.'' |title=Coding of sweet, bitter, and umami tastes: different receptor cells sharing similar signaling pathways. |journal=Cell |volume=112 |issue= 3 |pages= 293–301 |year= 2003 |pmid= 12581520 |doi=  }}
+*{{cite journal | vauthors = Go Y, Satta Y, Takenaka O, Takahata N | title = Lineage-Specific Loss of Function of Bitter Taste Receptor Genes in Humans and Nonhuman Primates | journal = Genetics | volume = 170 | issue = 1 | pages = 313–26 | year = 2006 | pmid = 15744053 | pmc = 1449719 | doi = 10.1534/genetics.104.037523 }}
-*{{cite journal  | author=Conte C, Ebeling M, Marcuz A, ''et al.'' |title=Identification and characterization of human taste receptor genes belonging to the TAS2R family. |journal=Cytogenet. Genome Res. |volume=98 |issue= 1 |pages= 45–53 |year= 2003 |pmid= 12584440 |doi= 10.1159/000068546 }}
-*{{cite journal  | author=Shi P, Zhang J, Yang H, Zhang YP |title=Adaptive diversification of bitter taste receptor genes in Mammalian evolution. |journal=Mol. Biol. Evol. |volume=20 |issue= 5 |pages= 805–14 |year= 2004 |pmid= 12679530 |doi= 10.1093/molbev/msg083 }}
-*{{cite journal  | author=Scherer SW, Cheung J, MacDonald JR, ''et al.'' |title=Human chromosome 7: DNA sequence and biology. |journal=Science |volume=300 |issue= 5620 |pages= 767–72 |year= 2003 |pmid= 12690205 |doi= 10.1126/science.1083423 }}
-*{{cite journal  | author=Gerhard DS, Wagner L, Feingold EA, ''et al.'' |title=The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). |journal=Genome Res. |volume=14 |issue= 10B |pages= 2121–7 |year= 2004 |pmid= 15489334 |doi= 10.1101/gr.2596504 }}
-*{{cite journal  | author=Fischer A, Gilad Y, Man O, Pääbo S |title=Evolution of bitter taste receptors in humans and apes. |journal=Mol. Biol. Evol. |volume=22 |issue= 3 |pages= 432–6 |year= 2005 |pmid= 15496549 |doi= 10.1093/molbev/msi027 }}
-*{{cite journal  | author=Go Y, Satta Y, Takenaka O, Takahata N |title=Lineage-specific loss of function of bitter taste receptor genes in humans and nonhuman primates. |journal=Genetics |volume=170 |issue= 1 |pages= 313–26 |year= 2006 |pmid= 15744053 |doi= 10.1534/genetics.104.037523 }}
-}}
 {{refend}}
-{{transmembranereceptor-stub}}
 {{NLM content}}
-{{G protein-coupled receptors}}
+{{G protein-coupled receptors|g3}}
-[[Category:G protein coupled receptors]]
+[[Category:Human taste receptors]]
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+{{transmembranereceptor-stub}}
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