(+)-pulegone reductase (EC 1.3.1.81) is an enzyme with systematic name (−)-menthone:NADP+ oxidoreductase.[1] This enzyme catalises the following chemical reaction
| (+)-pulegone reductase | |||||||||
|---|---|---|---|---|---|---|---|---|---|
| Identifiers | |||||||||
| EC no. | 1.3.1.81 | ||||||||
| Databases | |||||||||
| IntEnz | IntEnz view | ||||||||
| BRENDA | BRENDA entry | ||||||||
| ExPASy | NiceZyme view | ||||||||
| KEGG | KEGG entry | ||||||||
| MetaCyc | metabolic pathway | ||||||||
| PRIAM | profile | ||||||||
| PDB structures | RCSB PDB PDBe PDBsum | ||||||||
| |||||||||
- (1) (−)-menthone + NADP+ (+)-pulegone + NADPH + H+
- (2) (+)-isomenthone + NADP+ (+)-pulegone + NADPH + H+
NADH cannot replace NADPH as reductant.
References
edit- ^ Ringer KL, McConkey ME, Davis EM, Rushing GW, Croteau R (October 2003). "Monoterpene double-bond reductases of the (-)-menthol biosynthetic pathway: isolation and characterization of cDNAs encoding (-)-isopiperitenone reductase and (+)-pulegone reductase of peppermint". Archives of Biochemistry and Biophysics. 418 (1): 80–92. doi:10.1016/s0003-9861(03)00390-4. PMID 13679086.
External links
edit- (+)-pulegone+reductase at the U.S. National Library of Medicine Medical Subject Headings (MeSH)
