诺孕烯酮
外观
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臨床資料 | |
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商品名 | Ogyline, Planor, Miniplanor |
其他名稱 | RU-2010; A-301; 17α-Ethynyltrienolone; 17α-Ethynyltrenbolone; Δ9,11-Norethisterone; 17α-Ethynylestra-4,9,11-trien-17β-ol-3-one |
给药途径 | 口服给药 |
藥物類別 | Progestogen; Progestin; Androgen; Anabolic steroid |
ATC碼 | |
识别信息 | |
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CAS号 | 848-21-5 ![]() |
PubChem CID | |
ChemSpider | |
UNII | |
KEGG | |
CompTox Dashboard (EPA) | |
ECHA InfoCard | 100.011.544 |
化学信息 | |
化学式 | C20H22O2 |
摩尔质量 | 294.39 g·mol−1 |
3D模型(JSmol) | |
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诺孕烯酮(英語:Norgestrienone,或译为去甲孕三烯酮,商品名: Ogyline, Planor, Miniplanor 等)是一种甾体药物,分子式C20H22O2,由法国药企Roussel Uclaf开发,可用作复合口服避孕药,常与炔雌醇联用[1][2][3][4][5]。
参考文献
[编辑]- ^ Elks J. The Dictionary of Drugs: Chemical Data: Chemical Data, Structures and Bibliographies. Springer. 14 November 2014: 887–. ISBN 978-1-4757-2085-3.
- ^ Morton IK, Hall JM. Concise Dictionary of Pharmacological Agents: Properties and Synonyms. Springer Science & Business Media. 6 December 2012: 202– [2023-02-02]. ISBN 978-94-011-4439-1. (原始内容存档于2023-01-10).
- ^ Diaz S, Pavez M, Quinteros E, Diaz J, Robertson DN, Croxatto HB. Clinical trial with subdermal implants containing norgestrienone. Contraception. October 1978, 18 (4): 429–40. PMID 720075. doi:10.1016/0010-7824(78)90027-6.
- ^ Index Nominum 2000: International Drug Directory. Taylor & Francis. January 2000: 751–. ISBN 978-3-88763-075-1.
- ^ Sweetman, Sean C. (编). Sex hormones and their modulators. Martindale: The Complete Drug Reference 36th. London: Pharmaceutical Press. 2009: 2122 [2023-02-02]. ISBN 978-0-85369-840-1. (原始内容存档于2020-05-29).
Norgestrienone is a progestogen structurally related to norethisterone that has been used as an oral contraceptive. Typical doses have been 2 mg daily with an oestrogen, and 350 micrograms daily when used alone.