bortezomib &#160; Béarla (Q419319)

iompórtáilte ó thionscadal Vicipéide

inferred from InChIKey ^Béarla

úsáid

cógas

0 references

struchtúr ceimiceach

Bortezomib.svg
512 × 357; 6 KB

1 reference

Vicipéid na Gearmáinise

mais

384.197 aonad maise adamhaí

1 reference

PubChem ^Béarla

PubChem CID ^Béarla

179324-69-7 (Béarla)

19 Deireadh Fómhair 2016

stereoisomer of ^Béarla

N-[(1R)-1-Borono-3-methylbutyl]-Nalpha-(pyrazine-2-carbonyl)-D-phenylalaninamide ^Béarla

2 references

inferred from InChIKey ^Béarla

inferred from InChI ^Béarla

N-[(1S)-1-Borono-3-methylbutyl]-Nalpha-(pyrazine-2-carbonyl)-L-phenylalaninamide ^Béarla

1 reference

inferred from InChIKey ^Béarla

foirmle cheimiceach

C₁₉H₂₅BN₄O₄

1 reference

PubChem ^Béarla

PubChem CID ^Béarla

179324-69-7 (Béarla)

19 Samhain 2016

B(C(CC(C)C)NC(=O)C(CC1=CC=CC=C1)NC(=O)C2=NC=CN=C2)(O)O

1 reference

PubChem ^Béarla

PubChem CID ^Béarla

179324-69-7 (Béarla)

19 Samhain 2016

B([C@H](CC(C)C)NC(=O)[C@H](CC1=CC=CC=C1)NC(=O)C2=NC=CN=C2)(O)O

1 reference

PubChem ^Béarla

PubChem CID ^Béarla

179324-69-7 (Béarla)

19 Samhain 2016

active ingredient in ^Béarla

Bortezomib Accord ^Béarla

1 reference

European Medicines Agency product number ^Béarla

EMEA/H/C/003984

http://www.ema.europa.eu/ema/index.jsp?curl=pages/medicines/human/medicines/003984/human_med_001882.jsp

22 Márta 2017

Bortezomib Hospira ^Béarla

1 reference

European Medicines Agency product number ^Béarla

EMEA/H/C/004207

http://www.ema.europa.eu/ema/index.jsp?curl=pages/medicines/human/medicines/004207/human_med_001995.jsp

22 Márta 2017

Bortezomib Sun ^Béarla

1 reference

European Medicines Agency product number ^Béarla

EMEA/H/C/004076

http://www.ema.europa.eu/ema/index.jsp?curl=pages/medicines/human/medicines/004076/human_med_001996.jsp

22 Márta 2017

Velcade ^Béarla

1 reference

RxNorm ^Béarla

RxNorm ID ^Béarla

356733

14 Feabhra 2018

World Health Organisation international non-proprietary name ^Béarla

bortezomib (Béarla)

1 reference

ChEBI

ChEBI ID ^Béarla

52717

bortezomib (Béarla)

19 Deireadh Fómhair 2016

spriocghalar

mialóma iolrach

1 reference

NDF-RT ^Béarla

NDF-RT ID ^Béarla

N0000148811

13 Nollaig 2016

1 reference

2 Deireadh Fómhair 2018

plasmacytoma ^Béarla

1 reference

2 Deireadh Fómhair 2018

mantle cell lymphoma ^Béarla

1 reference

macraglóbailinéime Waldenström

2 Deireadh Fómhair 2018

1 reference

2 Deireadh Fómhair 2018

precursor T-cell lymphoblastic leukemia ^Béarla

1 reference

2 Deireadh Fómhair 2018

acute myeloid leukemia ^Béarla

1 reference

2 Deireadh Fómhair 2018

liomfóma neamh-Hodgkin

1 reference

2 Deireadh Fómhair 2018

plasma cell leukemia ^Béarla

1 reference

2 Deireadh Fómhair 2018

B-cell lymphoma ^Béarla

1 reference

2 Deireadh Fómhair 2018

diffuse large B-cell lymphoma ^Béarla

1 reference

2 Deireadh Fómhair 2018

significant drug interaction ^Béarla

fosphenytoin ^Béarla

side effect ^Béarla

peripheral neuropathy ^Béarla

1 reference

imthosca na foinse

go hipitéiseach

A reference set of clinically relevant adverse drug-drug interactions ^Béarla

phenytoin ^Béarla

side effect ^Béarla

peripheral neuropathy ^Béarla

1 reference

imthosca na foinse

go hipitéiseach

A reference set of clinically relevant adverse drug-drug interactions ^Béarla

physically interacts with ^Béarla

Proteasome 20S subunit beta 5 ^Béarla

ról an ábhair

enzyme inhibitor ^Béarla

1 reference

IUPHAR/BPS Guide to PHARMACOLOGY ^Béarla

Guide to Pharmacology Ligand ID ^Béarla

6391

iompórtáilte ó thionscadal Vicipéide

17 Lúnasa 2016

pregnancy category ^Béarla

Australian pregnancy category C ^Béarla

1 reference

Vicipéid an Bhéarla

US pregnancy category D ^Béarla

1 reference

iompórtáilte ó thionscadal Vicipéide

Vicipéid an Bhéarla

LiverTox likelihood score ^Béarla

LiverTox toxicity likelihood category C ^Béarla

1 reference

LiverTox ^Béarla

8 Aibreán 2021

https://www.ncbi.nlm.nih.gov/books/n/livertox/Bortezomib

last update ^Béarla

30 Meán Fómhair 2017

déantóir

Pfizer

1 reference

https://www.pfizer.com/products/product-list

ról an ábhair

frith-neoplasmach

1 reference

Medical Subject Headings ^Béarla

MeSH descriptor ID ^Béarla

D000069286

InChI=1S/C19H25BN4O4/c1-13(2)10-17(20(27)28)24-18(25)15(11-14-6-4-3-5-7-14)23-19(26)16-12-21-8-9-22-16/h3-9,12-13,15,17,27-28H,10-11H2,1-2H3,(H,23,26)(H,24,25)/t15-,17-/m0/s1

15 Márta 2018

catagóir Commons

Bortezomib

0 references

Identifiers

InChI

1 reference

PubChem ^Béarla

PubChem CID ^Béarla

179324-69-7 (Béarla)

19 Samhain 2016

InChIKey ^Béarla

2 references

PubChem ^Béarla

PubChem CID ^Béarla

179324-69-7 (Béarla)

19 Samhain 2016

ChEBI release 2020-09-01 ^Béarla

uimhir CAS

179324-69-7

2 references

Global Substance Registration System ^Béarla

UNII ^Béarla

69G8BD63PP

bortezomib (Béarla)

19 Samhain 2016

InChIKey ^Béarla

CAS Common Chemistry ^Béarla

9 Aibreán 2021

https://commonchemistry.cas.org/detail?cas_rn=179324-69-7

ChemSpider ID ^Béarla

343402

1 reference

ChemSpider ^Béarla

ChemSpider ID ^Béarla

343402

Bortezomib (Béarla)

19 Samhain 2016

PubChem CID ^Béarla

2 references

PubChem ^Béarla

PubChem CID ^Béarla

179324-69-7 (Béarla)

19 Samhain 2016

matched by identifier from ^Béarla

InChIKey

InChIKey ^Béarla

Reaxys registry number ^Béarla

8723817

1 reference

ChEBI

ChEBI ID ^Béarla

52717

bortezomib (Béarla)

19 Deireadh Fómhair 2016

ChEBI ID ^Béarla

52717

mapping relation type ^Béarla

meaitseáil chruinn

2 references

ChEMBL ^Béarla

ChEMBL ID ^Béarla

CHEMBL325041

BORTEZOMIB (Béarla)

InChI=1S/C19H25BN4O4/c1-13(2)10-17(20(27)28)24-18(25)15(11-14-6-4-3-5-7-14)23-19(26)16-12-21-8-9-22-16/h3-9,12-13,15,17,27-28H,10-11H2,1-2H3,(H,23,26)(H,24,25)/t15-,17-/m0/s1

19 Samhain 2016

matched by identifier from ^Béarla

International Chemical Identifier ^Béarla

InChI

ChEMBL ID ^Béarla

CHEMBL325041

1 reference

ChEMBL ^Béarla

ChEMBL ID ^Béarla

CHEMBL325041

BORTEZOMIB (Béarla)

19 Samhain 2016

UniChem compound ID ^Béarla

503765

1 reference

splash10-016r-1397000000-e168634cfe7e1453d742

UniChem ^Béarla

SPLASH ^Béarla

0 references

HSDB ID ^Béarla

7666

1 reference

Hazardous Substances Data Bank ^Béarla

HSDB ID ^Béarla

7666

dáta foilsithe

28 Deireadh Fómhair 2019

BORTEZOMIB (Béarla)

10 Bealtaine 2021

DSSTox substance ID ^Béarla

DTXSID3040980

2 references

Mapping file of InChIStrings, InChIKeys and DTXSIDs for the EPA CompTox Dashboard ^Béarla

matched by identifier from ^Béarla

InChIKey

InChIKey ^Béarla

DSSTOX compound identifier ^Béarla

DTXCID1020980

0 references

LiverTox ID ^Béarla

Bortezomib

0 references

NSC number ^Béarla

681239

0 references

EC number ^Béarla

605-854-3

0 references

ECHA Substance Infocard ID ^Béarla

100.125.601

1 reference

ECHA Substance Infocard database ^Béarla

ECHA Substance Infocard ID ^Béarla

100.125.601

27 Nollaig 2018

N,N',N''-((2S,2'S,2''S)-(((1R,1'R,1''R)-(1,3,5,2,4,6-trioxatriborinane-2,4,6-triyl)tris(3-methylbutane-1,1-diyl))tris(azanediyl))tris(1-oxo-3-phenylpropane-2,1-diyl))tris(pyrazine-2-carboxamide) (Béarla)

quotation ^Béarla

CAS no.: 179324-69-7 (Béarla)

ATC code ^Béarla

L01XX32

1 reference

DrugBank ^Béarla

DrugBank ID ^Béarla

00188