tofacitinib &#160; Béarla (Q3530324)

https://www.chemicalprobes.org/tofacitinib

struchtúr ceimiceach

Tofacitinib.svg
512 × 347; 4 KB

0 references

mais

312.17 aonad maise adamhaí

1 reference

PubChem ^Béarla

PubChem CID ^Béarla

Tofacitinib (Béarla)

(3S,4S)-4-Methyl-3-(methyl-7H-pyrrolo[2,3-d]pyrimidin-4-ylamino)-beta-oxo-1-piperidinepropanenitrile ^Béarla

19 Deireadh Fómhair 2016

stereoisomer of ^Béarla

2 references

inferred from InChIKey ^Béarla

(3S,4R)-4-Methyl-3-(methyl-7H-pyrrolo[2,3-d]pyrimidin-4-ylamino)-beta-oxo-1-piperidinepropanenitrile ^Béarla

inferred from InChI ^Béarla

1 reference

(3R,4S)-4-Methyl-3-(methyl-7H-pyrrolo[2,3-d]pyrimidin-4-ylamino)-beta-oxo-1-piperidinepropanenitrile ^Béarla

inferred from InChI ^Béarla

1 reference

inferred from InChI ^Béarla

foirmle cheimiceach

C₁₆H₂₀N₆O

1 reference

PubChem ^Béarla

PubChem CID ^Béarla

Tofacitinib (Béarla)

19 Samhain 2016

CC1CCN(CC1N(C)C2=NC=NC3=C2C=CN3)C(=O)CC#N

1 reference

PubChem ^Béarla

PubChem CID ^Béarla

Tofacitinib (Béarla)

19 Samhain 2016

C[C@@H]1CCN(C[C@@H]1N(C)C2=NC=NC3=C2C=CN3)C(=O)CC#N

1 reference

PubChem ^Béarla

PubChem CID ^Béarla

Tofacitinib (Béarla)

19 Samhain 2016

defined daily dose ^Béarla

10 milligram

route of administration ^Béarla

riarachán béil

1 reference

https://www.whocc.no/atc_ddd_index/?code=L04AA29

active ingredient in ^Béarla

Xeljanz ^Béarla

1 reference

RxNorm ^Béarla

RxNorm ID ^Béarla

1357542

14 Feabhra 2018

World Health Organisation international non-proprietary name ^Béarla

tofacitinib (Béarla)

1 reference

ChEBI ^Béarla

ChEBI ID ^Béarla

tofacitinib (Béarla)

19 Deireadh Fómhair 2016

spriocghalar

polyarthritis ^Béarla

1 reference

2 Deireadh Fómhair 2018

osteoarthritis susceptibility 1 ^Béarla

1 reference

2 Deireadh Fómhair 2018

airtríteas

1 reference

2 Deireadh Fómhair 2018

ulcerative colitis ^Béarla

1 reference

2 Deireadh Fómhair 2018

alopecia areata ^Béarla

1 reference

2 Deireadh Fómhair 2018

baldness ^Béarla

1 reference

2 Deireadh Fómhair 2018

physically interacts with ^Béarla

Janus kinase 3 ^Béarla

ról an ábhair

enzyme inhibitor ^Béarla

1 reference

IUPHAR/BPS Guide to PHARMACOLOGY ^Béarla

Guide to Pharmacology Ligand ID ^Béarla

5677

17 Lúnasa 2016

legal status (medicine) ^Béarla

boxed warning ^Béarla

1 reference

https://nctr-crs.fda.gov/fdalabel/ui/spl-summaries/criteria/343802

iompórtáilte ó thionscadal Vicipéide

FDA-sourced list of all drugs with black box warnings (Use Download Full Results and View Query links. (Béarla)

pregnancy category ^Béarla

US pregnancy category C ^Béarla

1 reference

Vicipéid an Bhéarla

LiverTox likelihood score ^Béarla

LiverTox toxicity likelihood category E* ^Béarla

1 reference

LiverTox ^Béarla

8 Aibreán 2021

https://www.ncbi.nlm.nih.gov/books/n/livertox/Tofacitinib

last update ^Béarla

2 Nollaig 2020

ról an ábhair

protein kinase inhibitors ^Béarla

1 reference

Medical Subject Headings ^Béarla

MeSH descriptor ID ^Béarla

C479163

InChI=1S/C16H20N6O/c1-11-5-8-22(14(23)3-6-17)9-13(11)21(2)16-12-4-7-18-15(12)19-10-20-16/h4,7,10-11,13H,3,5,8-9H2,1-2H3,(H,18,19,20)/t11-,13+/m1/s1

15 Márta 2018

catagóir Commons

Tofacitinib

0 references

Identifiers

InChI

1 reference

PubChem ^Béarla

PubChem CID ^Béarla

Tofacitinib (Béarla)

19 Samhain 2016

InChIKey ^Béarla

2 references

PubChem ^Béarla

PubChem CID ^Béarla

Tofacitinib (Béarla)

19 Samhain 2016

ChEBI release 2020-09-01 ^Béarla

uimhir CAS

477600-75-2

2 references

UNII ^Béarla

tofacitinib (Béarla)

19 Samhain 2016

InChIKey ^Béarla

CAS Common Chemistry ^Béarla

10 Aibreán 2021

https://commonchemistry.cas.org/detail?cas_rn=477600-75-2

ChemSpider ID ^Béarla

8102425

1 reference

ChemSpider ^Béarla

ChemSpider ID ^Béarla

8102425

Tofacitinib (Béarla)

19 Samhain 2016

PubChem CID ^Béarla

2 references

PubChem ^Béarla

PubChem CID ^Béarla

Tofacitinib (Béarla)

19 Samhain 2016

InChIKey ^Béarla

Reaxys registry number ^Béarla

11647225

1 reference

ChEBI ^Béarla

ChEBI ID ^Béarla

tofacitinib (Béarla)

19 Deireadh Fómhair 2016

ChEBI ID ^Béarla

mapping relation type ^Béarla

meaitseáil chruinn

2 references

ChEMBL ^Béarla

ChEMBL ID ^Béarla

CHEMBL221959

TOFACITINIB (Béarla)

19 Samhain 2016

InChI=1S/C16H20N6O/c1-11-5-8-22(14(23)3-6-17)9-13(11)21(2)16-12-4-7-18-15(12)19-10-20-16/h4,7,10-11,13H,3,5,8-9H2,1-2H3,(H,18,19,20)/t11-,13+/m1/s1

International Chemical Identifier ^Béarla

InChI

ChEMBL ID ^Béarla

CHEMBL221959

1 reference

ChEMBL ^Béarla

ChEMBL ID ^Béarla

CHEMBL221959

TOFACITINIB (Béarla)

19 Samhain 2016

SureChEMBL ID ^Béarla

SCHEMBL322753

2 references

inferred from InChIKey ^Béarla

InChIKey ^Béarla

UniChem compound ID ^Béarla

540499

1 reference

UniChem ^Béarla

HSDB ID ^Béarla

8311

1 reference

Hazardous Substances Data Bank ^Béarla

HSDB ID ^Béarla

8311

dáta foilsithe

28 Deireadh Fómhair 2019

Tofacitinib (Béarla)

10 Bealtaine 2021

DSSTox substance ID ^Béarla

DTXSID90197271

2 references

Mapping file of InChIStrings, InChIKeys and DTXSIDs for the EPA CompTox Dashboard ^Béarla

InChIKey ^Béarla

DSSTOX compound identifier ^Béarla

DTXCID00119762

0 references

LiverTox ID ^Béarla

Tofacitinib

0 references

EC number ^Béarla

689-145-4

1 reference

ECHA Substance Infocard database ^Béarla

ECHA Substance Infocard ID ^Béarla

100.215.928

27 Nollaig 2018

3-Piperidinamine, 1-(cyanoacetyl)-4-methyl-N-methyl-N-1H-pyrrolo(2,3-d)pyrimidin-4-yl-, (3R,4R)- (Béarla)

quotation ^Béarla

CAS no.: 477600-75-2 (Béarla)

ECHA Substance Infocard ID ^Béarla

100.215.928

1 reference

ECHA Substance Infocard database ^Béarla

ECHA Substance Infocard ID ^Béarla

100.215.928

27 Nollaig 2018

3-Piperidinamine, 1-(cyanoacetyl)-4-methyl-N-methyl-N-1H-pyrrolo(2,3-d)pyrimidin-4-yl-, (3R,4R)- (Béarla)

quotation ^Béarla

CAS no.: 477600-75-2 (Béarla)

ATC code ^Béarla

L04AA29

1 reference

DrugBank ^Béarla

DrugBank ID ^Béarla

08895

Tofacitinib (Béarla)

dáta foilsithe

17 Samhain 2015

Guide to Pharmacology Ligand ID ^Béarla

5677

1 reference

IUPHAR/BPS Guide to PHARMACOLOGY ^Béarla

Guide to Pharmacology Ligand ID ^Béarla

5677

tofacitinib (Béarla)

19 Samhain 2016

MeSH descriptor ID ^Béarla

C479163

luaite mar

tofacitinib

1 reference

Medical Subject Headings ^Béarla

MeSH descriptor ID ^Béarla

C479163

14 Márta 2018

RxNorm ID ^Béarla

1357536

1 reference

UNII ^Béarla

tofacitinib (Béarla)

19 Samhain 2016

DrugBank ID ^Béarla

DB08895

1 reference

InChIKey ^Béarla

UNII ^Béarla

2 references

UNII ^Béarla

tofacitinib (Béarla)

19 Samhain 2016

InChIKey ^Béarla

MedlinePlus drug identifier ^Béarla

a613025

0 references

NDF-RT ID ^Béarla

N0000186059

1 reference

UNII ^Béarla

tofacitinib (Béarla)

19 Samhain 2016

Probes And Drugs ID ^Béarla

PD004666

0 references

DrugCentral ID ^Béarla

4713

1 reference

UniChem ^Béarla

KEGG ID ^Béarla

D09970

1 reference

ChEBI ^Béarla

ChEBI ID ^Béarla

tofacitinib (Béarla)

https://docs.openalex.org/download-snapshot/snapshot-data-format

19 Deireadh Fómhair 2016

PDB ligand ID ^Béarla

MI1

0 references

Freebase ID ^Béarla

/m/0gfhs9b

0 references

Microsoft Academic ID ^Béarla

2778886723

0 references

OpenAlex ID ^Béarla

1 reference

26 Eanáir 2022

PDB structure ID ^Béarla

3LXK

1 reference

Protein Data Bank ^Béarla

PDB structure ID ^Béarla

3LXK

3LXK (Béarla)

19 Deireadh Fómhair 2016

4OTI

1 reference

Protein Data Bank ^Béarla

PDB structure ID ^Béarla

4OTI

4OTI (Béarla)

19 Deireadh Fómhair 2016

3FUP

1 reference

Protein Data Bank ^Béarla

PDB structure ID ^Béarla

3FUP

3FUP (Béarla)

19 Deireadh Fómhair 2016

3LXN

1 reference

Protein Data Bank ^Béarla

PDB structure ID ^Béarla

3LXN

3LXN (Béarla)

19 Deireadh Fómhair 2016

3EYG

1 reference

Protein Data Bank ^Béarla

PDB structure ID ^Béarla

3EYG

3EYG (Béarla)

19 Deireadh Fómhair 2016

UMLS CUI ^Béarla

C2930696

1 reference

UNII ^Béarla

tofacitinib (Béarla)