alpha-ketoglutaric acid (Q306140)

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chemical compound

• α-ketoglutarate
• 2-ketoglutarate
• oxoglutarate
• 2-oxoglutarate
• oxoglutaric acid
• Α-Ketoglutaric acid
• 2-Oxo-1,5-pentanedioate
• 2-ketoglutaric acid
• 2-Oxo-1,5-pentanedioic acid
• 2-Oxopentanedioate
• 2-oxopentanedioic acid
• 2-oxoglutaric acid

edit

Language	Label	Description	Also known as
English	alpha-ketoglutaric acid	chemical compound	α-ketoglutarate 2-ketoglutarate oxoglutarate 2-oxoglutarate oxoglutaric acid Α-Ketoglutaric acid 2-Oxo-1,5-pentanedioate 2-ketoglutaric acid 2-Oxo-1,5-pentanedioic acid 2-Oxopentanedioate 2-oxopentanedioic acid 2-oxoglutaric acid

Statements

instance of

type of chemical entity

0 references

subclass of

fatty acid

0 references

biogenic acyclic ketone

0 references

part of

oxoglutarate:malate antiporter activity

subject has role

cargo

1 reference

stated in

Gene Ontology release 2020-05-02

chemical structure

Alpha-ketoglutaric acid.png
1,633 × 740; 14 KB

1 reference

imported from Wikimedia project

German Wikipedia

mass

146.022 dalton

1 reference

stated in

PubChem

PubChem CID

51

language of work or name

English

title

2-ketoglutaric acid (English)

retrieved

19 October 2016

chemical formula

C₅H₆O₅

1 reference

stated in

PubChem

PubChem CID

51

language of work or name

English

title

2-ketoglutaric acid (English)

retrieved

19 November 2016

canonical SMILES

C(CC(=O)O)C(=O)C(=O)O

1 reference

stated in

PubChem

PubChem CID

51

language of work or name

English

title

2-ketoglutaric acid (English)

retrieved

19 November 2016

melting point

115.0 degree Celsius

1 reference

stated in

Jean-Claude Bradley Open Melting Point Dataset

found in taxon

Pycnandra acuminata

1 reference

stated in

LC–MS and GC–MS metabolite profiling of nickel(II) complexes in the latex of the nickel-hyperaccumulating tree Sebertia acuminata and identification of methylated aldaric acid as a new nickel(II) ligand

Chlamydomonas reinhardtii

1 reference

stated in

The response of Chlamydomonas reinhardtii to nitrogen deprivation: a systems biology analysis

Phycomyces blakesleeanus

1 reference

stated in

Acidic metabolites from Phycomyces blakesleeanus

Fasciola hepatica

1 reference

stated in

Some Acids Belonging to the Citric Acid Cycle in the Liver Fluke, Fasciola hepatica, L.

Streptomyces albus

1 reference

stated in

Über die Bildung von DL-Alanin in Kulturen einer Mutante vonStreptomyces albus var. metamycinusJA 3626

Homo sapiens

2 references

stated in

Recon 2.2: from reconstruction to model of human metabolism

stated in

A community-driven global reconstruction of human metabolism.

Streptomyces venezuelae

1 reference

stated in

Excretion of alpha-keto acids by strains of Streptomyces venezuelae

Streptomyces hygroscopicus

1 reference

stated in

Induzierbare Akkumulation von α-Ketoglutarsäure in Kulturen eines Makrolidantibioticum-bildenden Stammes vonStreptomyces hygroscopicus JA 6599

Caenorhabditis elegans

3 references

stated in

Modeling Meets Metabolomics-The WormJam Consensus Model as Basis for Metabolic Studies in the Model Organism

stated in

Metabotyping of the C. elegans sir-2.1 mutant using in vivo labeling and (13)C-heteronuclear multidimensional NMR metabolomics

stated in

Comparison of proteomic and metabolomic profiles of mutants of the mitochondrial respiratory chain in Caenorhabditis elegans

Murraya paniculata

1 reference

stated in

Metabolomic comparative analysis of the phloem sap of curry leaf tree (Bergera koenegii), orange jasmine (Murraya paniculata), and Valencia sweet orange (Citrus sinensis) supports their differential responses to Huanglongbing.

Escherichia coli

1 reference

stated in

Investigation on response of the metabolites in tricarboxylic acid cycle of Escherichi coli and Pseudomonas aeruginosa to antibiotic perturbation by capillary electrophoresis.

common sunflower

1 reference

stated in

Metabolic profiles of sunflower genotypes with contrasting response to Sclerotinia sclerotiorum infection

Humulus lupulus

1 reference

stated in

Transcriptome analysis of bitter acid biosynthesis and precursor pathways in hop (Humulus lupulus).

Spinacia oleracea

1 reference

stated in

Differences in the metabolite profiles of spinach (Spinacia oleracea L.) leaf in different concentrations of nitrate in the culture solution

Cucurbita

1 reference

stated in

Separation and characterisation of three 2-oxoglutarate-dependent dioxygenases from Cucurbita maxima L. endosperm involved in gibberellin biosynthesis

Phaseolus vulgaris

1 reference

stated in

Metabolomics and Transcriptomics Identify Multiple Downstream Targets of Paraburkholderia phymatum σ54 During Symbiosis with Phaseolus vulgaris.

Pisum sativum

1 reference

stated in

Products of Dark CO(2) Fixation in Pea Root Nodules Support Bacteroid Metabolism

Oryza sativa

2 references

stated in

Simultaneous determination of the main metabolites in rice leaves using capillary electrophoresis mass spectrometry and capillary electrophoresis diode array detection

stated in

Metabolic Plasticity and Inter-Compartmental Interactions in Rice Metabolism: An Analysis from Reaction Deletion Study

Streptomyces caespitosus

1 reference

stated in

Effect of sodium arsenite on the biosynthesis of mitomycins by Streptomyces caespitosus and mode of action of mitomycin C on Bacillus subtilis NRRL B-543

tomato

1 reference

stated in

Metabolite content of harvested Micro-Tom tomato (Solanum lycopersicum L.) fruit is altered by chilling and protective heat-shock treatments as shown by GC–MS metabolic profiling

medical condition treated

kidney failure

approved by

Food and Drug Administration

1 reference

stated in

Inxight: Drugs Database

retrieved

2 November 2018

reference URL

https://drugs.ncats.io/drug/8ID597Z82X

http://naturaldatabase.therapeuticresearch.com/nd/PrintVersion.aspx?id=144&AspxAutoDetectCookieSupport=1

http://www.webmd.com/vitamins-supplements/ingredientmono-144-alpha-ketoglutarate.aspx?activeingredientid=144&activeingredientname=alpha-ketoglutarate

physically interacts with

Oxoglutarate receptor 1

subject has role

agonist

1 reference

stated in

IUPHAR/BPS Guide to PHARMACOLOGY

Guide to Pharmacology Ligand ID

3636

language of work or name

English

retrieved

17 August 2016

has part(s)

oxygen

0 references

carbon

0 references

Commons category

Alpha-ketoglutaric acid

0 references

Identifiers

InChI

InChI=1S/C5H6O5/c6-3(5(9)10)1-2-4(7)8/h1-2H2,(H,7,8)(H,9,10)

1 reference

stated in

PubChem

PubChem CID

51

language of work or name

English

title

2-ketoglutaric acid (English)

retrieved

19 November 2016

InChIKey

KPGXRSRHYNQIFN-UHFFFAOYSA-N

2 references

stated in

PubChem

PubChem CID

51

language of work or name

English

title

2-ketoglutaric acid (English)

retrieved

19 November 2016

stated in

ChEBI release 2020-09-01

CAS Registry Number

328-50-7

2 references

stated in

Global Substance Registration System

UNII

8ID597Z82X

language of work or name

English

title

oxogluric acid (English)

retrieved

19 November 2016

InChIKey

KPGXRSRHYNQIFN-UHFFFAOYSA-N

stated in

CAS Common Chemistry

retrieved

10 April 2021

reference URL

https://commonchemistry.cas.org/detail?cas_rn=328-50-7

ChemSpider ID

50

1 reference

stated in

ChemSpider

ChemSpider ID

50

language of work or name

English

title

alpha-Ketoglutaric acid (English)

retrieved

19 November 2016

PubChem CID

51

2 references

stated in

PubChem

PubChem CID

51

language of work or name

English

title

2-ketoglutaric acid (English)

retrieved

19 November 2016

matched by identifier from

InChIKey

InChIKey

KPGXRSRHYNQIFN-UHFFFAOYSA-N

156274072

1 reference

matched by identifier from

InChIKey

InChIKey

KPGXRSRHYNQIFN-UHFFFAOYSA-N

Reaxys registry number

1705689

1 reference

stated in

ChEBI

ChEBI ID

30915

language of work or name

English

title

2-oxoglutaric acid (English)

retrieved

19 October 2016

Gmelin number

602480

0 references

ChEBI ID

30915

mapping relation type

exact match

2 references

stated in

ChEMBL

ChEMBL ID

CHEMBL1686

language of work or name

English

title

ALPHA-KETOGLUTARIC ACID (English)

retrieved

19 November 2016

matched by identifier from

International Chemical Identifier

InChI

InChI=1S/C5H6O5/c6-3(5(9)10)1-2-4(7)8/h1-2H2,(H,7,8)(H,9,10)

ChEMBL ID

CHEMBL1686

1 reference

stated in

ChEMBL

ChEMBL ID

CHEMBL1686

language of work or name

English

title

ALPHA-KETOGLUTARIC ACID (English)

retrieved

19 November 2016

UniChem compound ID

72549

1 reference

stated in

UniChem

MassBank accession ID

MSBNK-NAIST-KNA00530

0 references

MSBNK-NAIST-KNA00531

0 references

MSBNK-NAIST-KNA00533

0 references

MSBNK-NAIST-KNA00700

0 references

MSBNK-NAIST-KNA00701

0 references

MSBNK-NAIST-KNA00702

0 references

MSBNK-Osaka_Univ-OUF00113

0 references

MSBNK-RIKEN-PR010210

0 references

MSBNK-Kazusa-KZ000080

0 references

MSBNK-Keio_Univ-KO001528

0 references

MSBNK-Keio_Univ-KO001529

0 references

MSBNK-Keio_Univ-KO001530

0 references

MSBNK-Keio_Univ-KO001531

0 references

SPLASH

splash10-0002-0900000000-c3c62f83bff99f44f7ab

0 references

splash10-0zfr-6900000000-b6d8379db3e3f1480b14

0 references

splash10-0a4i-9300000000-4fde39bb93cde5a27f23

0 references

splash10-00i0-9000000000-4343832f3a55842423a9

0 references

splash10-0002-0925200000-37db185093f01ca47a55

0 references

splash10-0a4i-9000000000-6e43f767847790112b65

0 references

splash10-0udi-0900000000-1367eeeb6ad64c67a0aa

0 references

splash10-000t-0915051100-f82c99c58327e411a2bc

0 references

splash10-0a4i-9000000000-4f842c3673925d29c402

0 references

splash10-0udi-0900000000-5e751351656f6eb62de3

0 references

splash10-0002-1910000000-3277227b9c4da4baa1f7

0 references

splash10-00di-9300000000-974bce546caa4fbe6b0f

0 references

splash10-0002-0900000000-ac1341c26718f471f281

0 references

splash10-000b-2900000000-e514f7afea2490bbe9ed

0 references

splash10-0zfr-6900000000-7fc343a243ce5d2a4f39

0 references

splash10-052s-4920000000-bf7ed92c68fd4c8dbb6b

0 references

splash10-000i-9710000000-d0aea11e947b042571f9

0 references

splash10-0fba-9200000000-4e367c66e94c51eb1a1b

0 references

splash10-0a4l-9800000000-30495b2afdd3526854e7

0 references

splash10-0a4i-9200000000-1a7af9946604baa8b3d2

0 references

NMRShiftDB structure ID

30095876

1 reference

matched by identifier from

InChIKey

InChIKey

KPGXRSRHYNQIFN-UHFFFAOYSA-N

DSSTox substance ID

DTXSID5033179

2 references

stated in

Mapping file of InChIStrings, InChIKeys and DTXSIDs for the EPA CompTox Dashboard

matched by identifier from

InChIKey

InChIKey

KPGXRSRHYNQIFN-UHFFFAOYSA-N

DSSTOX compound identifier

DTXCID3013179

0 references

NSC number

17391

0 references

EC number

206-330-3

1 reference

stated in

Global Substance Registration System

UNII

8ID597Z82X

language of work or name

English

title

oxogluric acid (English)

retrieved

19 November 2016

ECHA Substance Infocard ID

100.005.756

1 reference

stated in

ECHA Substance Infocard database

ECHA Substance Infocard ID

100.005.756

retrieved

27 December 2018

title

2-oxoglutaric acid (English)

quotation

CAS no.: 328-50-7 (English)

FL number

08.037

1 reference

quotation

CAS no.: 328-50-7 (English)

stated in

EFSA database

retrieved

23 January 2021

FL number

08.037

CosIng number

34798

1 reference

stated in

CosIng database

CosIng number

34798

retrieved

28 December 2019

title

KETOGLUTARIC ACID (English)

quotation

CAS no.: 328-50-7 (English)

Cannabis Database ID

006340

1 reference

stated in

Cannabis Database

UM-BBD compound ID

c0880

0 references

Guide to Pharmacology Ligand ID

3636

1 reference

stated in

IUPHAR/BPS Guide to PHARMACOLOGY

Guide to Pharmacology Ligand ID

3636

language of work or name

English

title

α-ketoglutaric acid (English)

retrieved

19 November 2016

RxNorm ID

17511

1 reference

stated in

Global Substance Registration System

UNII

8ID597Z82X

language of work or name

English

title

oxogluric acid (English)

retrieved

19 November 2016

DrugBank ID

DB08845

1 reference

matched by identifier from

InChIKey

InChIKey

KPGXRSRHYNQIFN-UHFFFAOYSA-N

Human Metabolome Database ID

HMDB0000208

2 references

based on heuristic

inferred from InChIKey

matched by identifier from

InChIKey

InChIKey

KPGXRSRHYNQIFN-UHFFFAOYSA-N

KNApSAcK ID

C00000769

3 references

stated in

ChEBI

ChEBI ID

30915

language of work or name

English

title

2-oxoglutaric acid (English)

retrieved

19 October 2016

based on heuristic

inferred from InChIKey

matched by identifier from

InChIKey

InChIKey

KPGXRSRHYNQIFN-UHFFFAOYSA-N

UNII

8ID597Z82X

2 references

stated in

Global Substance Registration System

UNII

8ID597Z82X

language of work or name

English

title

oxogluric acid (English)

retrieved

19 November 2016

matched by identifier from

InChIKey

InChIKey

KPGXRSRHYNQIFN-UHFFFAOYSA-N

Probes And Drugs ID

PD014389

0 references

KEGG ID

C00026

1 reference

imported from Wikimedia project

English Wikipedia

PDB ligand ID

AKG

0 references

Encyclopædia Britannica Online ID

topic/alpha-oxoglutarate

subject named as

alpha-oxoglutarate

0 references

Freebase ID

/m/04f03

1 reference

stated in

Freebase Data Dumps

publication date

28 October 2013

Google Knowledge Graph ID

/g/11jp2r8t5d

0 references

Great Russian Encyclopedia portal ID

al-fa-ketoglutarovaia-kislota-854344

0 references

JECFA number

634

1 reference

stated in

Evaluations of the Joint FAO/WHO Expert Committee on Food Additives (JECFA)

retrieved

13 May 2021

Microsoft Academic ID

2776215227

0 references

OpenAlex ID

C2910453370

1 reference

stated in

OpenAlex

retrieved

26 January 2022

reference URL

https://docs.openalex.org/download-snapshot/snapshot-data-format

 

Sitelinks

Wikipedia(30 entries)

edit

• arwiki ألفا-كيتوغلوتارات
• azbwiki آلفا-کتوقلوتاریک اسید
• cswiki 2-oxoglutarát
• dawiki Alfa-ketoglutarat
• dewiki Α-Ketoglutarsäure
• enwiki Α-Ketoglutaric acid
• eswiki Ácido α-cetoglutárico
• fawiki آلفا-کتوگلوتاریک اسید
• fiwiki Alfaketoglutaarihappo
• frwiki Acide alpha-cétoglutarique
• glwiki Ácido alfa-cetoglutárico
• huwiki 2-Oxopentándisav
• itwiki Acido 2-chetoglutarico
• jawiki Α-ケトグルタル酸
• kowiki 알파-케토글루타르산
• mkwiki Алфа-кетоглутарна киселина
• mswiki Asid alfa-ketoglutarik
• nlwiki Alfa-ketoglutaarzuur
• plwiki Kwas α-ketoglutarowy
• ptwiki Ácido alfacetoglutárico
• rowiki Acid alfa-cetoglutaric
• ruwiki Альфа-кетоглутаровая кислота
• shwiki Alfa-Ketoglutarna kiselina
• simplewiki Α-Ketoglutaric acid
• skwiki 2-oxoglutarát
• srwiki Alfa-Ketoglutarna kiselina
• svwiki Alfa-ketoglutarsyra
• ukwiki Α-кетоглутарова кислота
• urwiki الفا-کیٹوگلوٹارک تیزاب
• zhwiki Α-酮戊二酸

Wikibooks(0 entries)

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Wikinews(0 entries)

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Wikiquote(0 entries)

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Wikisource(0 entries)

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Wikiversity(0 entries)

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Wikivoyage(0 entries)

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Wiktionary(0 entries)

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Multilingual sites(1 entry)

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• commonswiki Category:Alpha-ketoglutaric acid

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