Eukaryotic translation elongation factor 2 (Q21173658)

http://www.ebi.ac.uk/interpro/protein/P13639

Ribosomal protein S5 domain 2-type fold

1 reference

http://www.ebi.ac.uk/interpro/protein/P13639

Ribosomal protein S5 domain 2-type fold, subgroup

1 reference

http://www.ebi.ac.uk/interpro/protein/P13639

P-loop containing nucleoside triphosphate hydrolase

1 reference

http://www.ebi.ac.uk/interpro/protein/P13639

Translation protein, beta-barrel domain superfamily

1 reference

http://www.ebi.ac.uk/interpro/protein/P13639

membrane protein

1 reference

inferred from GOA cell component → membrane

Elongation factor EFG, domain V-like, protein family

1 reference

Translation elongation factor EFTu-like, domain 2, protein family

1 reference

Translation elongation factor EFG/EF2, domain IV, protein family

1 reference

Transcription factor, GTP-binding domain, protein family

1 reference

Small GTP-binding protein domain family

1 reference

Tr-type G domain, conserved site, protein family

1 reference

1 reference

13 November 2019

1 reference

13 November 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P13639

1 reference

8 April 2019

ribosome binding

1 reference

26 September 2017

http://www.ebi.ac.uk/QuickGO/annotations?protein=P13639&geneProductId=UniProtKB:P13639

p53 binding

1 reference

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P13639

translation elongation factor activity

http://www.ebi.ac.uk/QuickGO/annotations?protein=P13639&geneProductId=UniProtKB:P13639

1 reference

26 September 2017

actin filament binding

1 reference

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P13639

protein binding

5 references

8 April 2019

SMG-8 and SMG-9, two novel subunits of the SMG-1 complex, regulate remodeling of the mRNA surveillance complex during nonsense-mediated mRNA decay

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P13639

8 April 2019

Identification and characterization of a novel evolutionarily conserved lysine-specific methyltransferase targeting eukaryotic translation elongation factor 2 (eEF2)

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P13639

8 April 2019

Homodimerization of RBPMS2 through a new RRM-interaction motif is necessary to control smooth muscle plasticity

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P13639

8 April 2019

A Map of Human Mitochondrial Protein Interactions Linked to Neurodegeneration Reveals New Mechanisms of Redox Homeostasis and NF-κB Signaling

IntAct protein interaction database

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P13639

8 April 2019

Systematic Analysis Reveals Elongation Factor 2 and α-Enolase as Novel Interaction Partners of AKT2

IntAct protein interaction database

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P13639

5S rRNA binding

1 reference

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P13639

protein kinase binding

1 reference

8 April 2019

Systematic Analysis Reveals Elongation Factor 2 and α-Enolase as Novel Interaction Partners of AKT2

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P13639

RNA binding

3 references

26 September 2017

http://www.ebi.ac.uk/QuickGO/annotations?protein=P13639&geneProductId=UniProtKB:P13639

26 September 2017

The mRNA-bound proteome and its global occupancy profile on protein-coding transcripts

http://www.ebi.ac.uk/QuickGO/annotations?protein=P13639&geneProductId=UniProtKB:P13639

26 September 2017

Insights into RNA biology from an atlas of mammalian mRNA-binding proteins

http://www.ebi.ac.uk/QuickGO/annotations?protein=P13639&geneProductId=UniProtKB:P13639

cadherin binding

1 reference

26 September 2017

E-cadherin interactome complexity and robustness resolved by quantitative proteomics

British Heart Foundation

http://www.ebi.ac.uk/QuickGO/annotations?protein=P13639&geneProductId=UniProtKB:P13639

RNA binding

3 references

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P13639

8 April 2019

The mRNA-bound proteome and its global occupancy profile on protein-coding transcripts

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P13639

8 April 2019

Insights into RNA biology from an atlas of mammalian mRNA-binding proteins

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P13639

GTPase activity

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P13639

3 references

8 April 2019

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P13639

8 April 2019

Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P13639

cadherin binding

1 reference

8 April 2019

E-cadherin interactome complexity and robustness resolved by quantitative proteomics

British Heart Foundation

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P13639

cell component

cytoplasm

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P13639

3 references

8 April 2019

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P13639

8 April 2019

Homodimerization of RBPMS2 through a new RRM-interaction motif is necessary to control smooth muscle plasticity

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P13639

polysome

1 reference

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P13639

membrane

1 reference

26 September 2017

Defining the membrane proteome of NK cells

http://www.ebi.ac.uk/QuickGO/annotations?protein=P13639&geneProductId=UniProtKB:P13639

plasma membrane

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P13639

1 reference

8 April 2019

aggresome

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P13639

1 reference

8 April 2019

membrane raft

1 reference

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P13639

extracellular exosome

5 references

26 September 2017

Proteomic analysis of podocyte exosome-enriched fraction from normal human urine

http://www.ebi.ac.uk/QuickGO/annotations?protein=P13639&geneProductId=UniProtKB:P13639

26 September 2017

Large-scale proteomics and phosphoproteomics of urinary exosomes

http://www.ebi.ac.uk/QuickGO/annotations?protein=P13639&geneProductId=UniProtKB:P13639

26 September 2017

Proteomic analysis of human parotid gland exosomes by multidimensional protein identification technology (MudPIT)

http://www.ebi.ac.uk/QuickGO/annotations?protein=P13639&geneProductId=UniProtKB:P13639

26 September 2017

In-depth proteomic analyses of exosomes isolated from expressed prostatic secretions in urine

http://www.ebi.ac.uk/QuickGO/annotations?protein=P13639&geneProductId=UniProtKB:P13639

26 September 2017

MHC class II-associated proteins in B-cell exosomes and potential functional implications for exosome biogenesis

http://www.ebi.ac.uk/QuickGO/annotations?protein=P13639&geneProductId=UniProtKB:P13639

polysomal ribosome

1 reference

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P13639

extracellular matrix

1 reference

26 September 2017

SILAC-based proteomics of human primary endothelial cell morphogenesis unveils tumor angiogenic markers

British Heart Foundation

http://www.ebi.ac.uk/QuickGO/annotations?protein=P13639&geneProductId=UniProtKB:P13639

extracellular region

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P13639

1 reference

8 April 2019

cytosol

http://www.ebi.ac.uk/QuickGO/annotations?protein=P13639&geneProductId=UniProtKB:P13639

3 references

26 September 2017

26 September 2017

http://www.ebi.ac.uk/QuickGO/annotations?protein=P13639&geneProductId=UniProtKB:P13639

http://www.ebi.ac.uk/QuickGO/annotations?protein=P13639&geneProductId=UniProtKB:P13639

26 September 2017

secretory granule lumen

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P13639

1 reference

8 April 2019

ficolin-1-rich granule lumen

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P13639

1 reference

8 April 2019

cytosol

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P13639

4 references

8 April 2019

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P13639

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P13639

8 April 2019

8 April 2019

Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P13639

membrane

1 reference

8 April 2019

Defining the membrane proteome of NK cells

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P13639

synapse

1 reference

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P13639

extracellular exosome

4 references

8 April 2019

Proteomic analysis of human parotid gland exosomes by multidimensional protein identification technology (MudPIT)

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P13639

8 April 2019

MHC class II-associated proteins in B-cell exosomes and potential functional implications for exosome biogenesis

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P13639

8 April 2019

Large-scale proteomics and phosphoproteomics of urinary exosomes

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P13639

8 April 2019

In-depth proteomic analyses of exosomes isolated from expressed prostatic secretions in urine

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P13639

ribonucleoprotein complex

3 references

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P13639

8 April 2019

Nucleophosmin serves as a rate-limiting nuclear export chaperone for the Mammalian ribosome

Mouse Genome Informatics

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P13639

8 April 2019

Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P13639

biological process

response to estradiol

1 reference

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P13639

positive regulation of cytoplasmic translation

1 reference

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P13639

skeletal muscle contraction

1 reference

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P13639

translational elongation

http://www.ebi.ac.uk/QuickGO/annotations?protein=P13639&geneProductId=UniProtKB:P13639

3 references

26 September 2017

http://www.ebi.ac.uk/QuickGO/annotations?protein=P13639&geneProductId=UniProtKB:P13639

26 September 2017

26 September 2017

http://www.ebi.ac.uk/QuickGO/annotations?protein=P13639&geneProductId=UniProtKB:P13639

human ageing

1 reference

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P13639

positive regulation of translation

response to endoplasmic reticulum stress

IMP

1 reference

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P13639

cellular response to brain-derived neurotrophic factor stimulus

1 reference

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P13639

response to ischemia

1 reference

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P13639

hematopoietic progenitor cell differentiation

1 reference

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P13639

peptidyl-diphthamide biosynthetic process from peptidyl-histidine

http://www.ebi.ac.uk/QuickGO/annotations?protein=P13639&geneProductId=UniProtKB:P13639

1 reference

26 September 2017

glial cell proliferation

1 reference

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P13639

skeletal muscle cell differentiation

1 reference

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P13639

response to folic acid

1 reference

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P13639

response to ethanol

1 reference

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P13639

response to hydrogen peroxide

1 reference

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P13639

protein biosynthesis

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P13639

1 reference

8 April 2019

protein methylation

http://www.ebi.ac.uk/QuickGO/annotations?protein=P13639&geneProductId=UniProtKB:P13639

1 reference

26 September 2017

neutrophil degranulation

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P13639

1 reference

8 April 2019

translational elongation

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P13639

4 references

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P13639

8 April 2019

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P13639

8 April 2019

Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P13639

physically interacts with

denileukin diftitox

object of statement has role

reaction inhibitor

1 reference

Open Targets Platform

14 August 2023

https://platform.opentargets.org/drug/CHEMBL1201550

has part(s)

transcription factor, GTP-binding domain

1 reference

http://www.ebi.ac.uk/interpro/protein/P13639

translation elongation factor EFG/EF2, domain IV

1 reference

http://www.ebi.ac.uk/interpro/protein/P13639

elongation factor EFG, domain V-like

1 reference

http://www.ebi.ac.uk/interpro/protein/P13639

Tr-type G domain, conserved site

1 reference

http://www.ebi.ac.uk/interpro/protein/P13639

small GTP-binding protein domain

1 reference

http://www.ebi.ac.uk/interpro/protein/P13639

translation elongation factor EFTu-like, domain 2

1 reference