novobiocin (Q1639291)

Gene Ontology release 2019-11-16

novobiocin biosynthetic process

subject has role

product

1 reference

Gene Ontology release 2019-11-16

1 reference

Novobiocin (English)

image of molecular model or crystal lattice model

17 November 2015

Novobiocin2DCSD.svg
1,200 × 435; 30 KB

0 references

Novobiocin molecule ball.png
2,000 × 1,184; 485 KB

depicts

ball-and-stick model

0 references

mass

612.232 dalton

1 reference

[(3R,4S,5R,6S)-5-hydroxy-6-[4-hydroxy-3-[[4-hydroxy-3-(3-methylbut-2-enyl)benzoyl]amino]-8-methyl-2-oxochromen-7-yl]oxy-3-methoxy-2,2-dimethyloxan-4-yl] carbamate

novobiocin (English)

19 October 2016

1 reference

based on heuristic

inferred from InChI

[(3R,4R,5S,6R)-5-hydroxy-6-[4-hydroxy-3-[[4-hydroxy-3-(3-methylbut-2-enyl)benzoyl]amino]-8-methyl-2-oxochromen-7-yl]oxy-3-methoxy-2,2-dimethyloxan-4-yl] carbamate

1 reference

based on heuristic

inferred from InChI

chemical formula

C₃₁H₃₆N₂O₁₁

1 reference

novobiocin (English)

19 November 2016

CC1=C(C=CC2=C1OC(=O)C(=C2O)NC(=O)C3=CC(=C(C=C3)O)CC=C(C)C)OC4C(C(C(C(O4)(C)C)OC)OC(=O)N)O

1 reference

novobiocin (English)

19 November 2016

CC1=C(C=CC2=C1OC(=O)C(=C2O)NC(=O)C3=CC(=C(C=C3)O)CC=C(C)C)O[C@H]4[C@@H]([C@@H]([C@H](C(O4)(C)C)OC)OC(=O)N)O

1 reference

A comprehensive genome-scale reconstruction of Escherichia coli metabolism--2011.

novobiocin (English)

19 November 2016

1 reference

Nocardiopsis gilva

1 reference

Isolation and characterization of new p-Terphenyls with antifungal, antibacterial, and antioxidant activities from halophilic actinomycete Nocardiopsis gilva YIM 90087.

Streptomyces

1 reference

Tyrosine derivatives isolated from Streptomyces sp. IFM 10937 in a screening program for TRAIL-resistance-overcoming activity

Actinoalloteichus cyanogriseus

8 references

Studies on the biosynthesis of terpenoid compounds produced by actinomycetes. 3. Biosynthesis of the isoprenoid side chain of novobiocin via the non-mevalonate pathway in Streptomyces niveus

Biosynthesis of novobiocin by Streptomyces niveus

High frequency transformation of Streptomyces niveus protoplasts by plasmid DNA

Induction of resistance to novobiocin in the novobiocin-producing organismStreptomyces niveus

Cloning, overexpression, and purification of novobiocic acid synthetase from Streptomyces spheroides NCIMB 11891.

Biosynthesis of the dimethylallyl moiety of novobiocin via a non-mevalonate pathway

Degeneration of Streptomyces niveus with Repeated Transfers

Identification of the novobiocin biosynthetic gene cluster of Streptomyces spheroides NCIB 11891

Streptomyces niveus

8 references

Studies on the biosynthesis of terpenoid compounds produced by actinomycetes. 3. Biosynthesis of the isoprenoid side chain of novobiocin via the non-mevalonate pathway in Streptomyces niveus

Biosynthesis of novobiocin by Streptomyces niveus

High frequency transformation of Streptomyces niveus protoplasts by plasmid DNA

Induction of resistance to novobiocin in the novobiocin-producing organismStreptomyces niveus

Cloning, overexpression, and purification of novobiocic acid synthetase from Streptomyces spheroides NCIMB 11891.

Biosynthesis of the dimethylallyl moiety of novobiocin via a non-mevalonate pathway

Degeneration of Streptomyces niveus with Repeated Transfers

Identification of the novobiocin biosynthetic gene cluster of Streptomyces spheroides NCIB 11891

Streptomyces albidoflavus

3 references

Production of 8'-halogenated and 8'-unsubstituted novobiocin derivatives in genetically engineered streptomyces coelicolor strains.

Cytochrome p450 complement (CYPome) of the avermectin-producer Streptomyces avermitilis and comparison to that of Streptomyces coelicolor A3(2).

DNA affinity capturing identifies new regulators of the heterologously expressed novobiocin gene cluster in Streptomyces coelicolor M512.

Streptomyces coelicolor

3 references

Production of 8'-halogenated and 8'-unsubstituted novobiocin derivatives in genetically engineered streptomyces coelicolor strains.

Cytochrome p450 complement (CYPome) of the avermectin-producer Streptomyces avermitilis and comparison to that of Streptomyces coelicolor A3(2).

DNA affinity capturing identifies new regulators of the heterologously expressed novobiocin gene cluster in Streptomyces coelicolor M512.

subject has role

antibiotic

1 reference

Medical Subject Headings

15 March 2018

1 reference

Medical Subject Headings

MeSH descriptor ID

D009675

DNA polymerase inhibitors

15 March 2018

1 reference

InChI=1S/C31H36N2O11/c1-14(2)7-8-16-13-17(9-11-19(16)34)27(37)33-21-22(35)18-10-12-20(15(3)24(18)42-28(21)38)41-29-23(36)25(43-30(32)39)26(40-6)31(4,5)44-29/h7,9-13,23,25-26,29,34-36H,8H2,1-6H3,(H2,32,39)(H,33,37)/t23-,25+,26-,29-/m1/s1

Medical Subject Headings

15 March 2018

Novobiocin

0 references

Identifiers

InChI

1 reference

novobiocin (English)

19 November 2016

2 references

novobiocin (English)

19 November 2016

ChEBI release 2020-09-01

CAS Registry Number

303-81-1

2 references

novobiocin (English)

19 November 2016

https://commonchemistry.cas.org/detail?cas_rn=303-81-1

9 April 2021

1 reference

novobiocin (English)

19 November 2016

2 references

English

title

novobiocin (English)

19 November 2016

Reaxys registry number

1445842

1 reference

novobiocin (English)

19 October 2016

mapping relation type

3 references

NOVOBIOCIN (English)

19 November 2016

ChEBI release 2019-10-02

International Chemical Identifier

InChI

InChI=1S/C31H36N2O11/c1-14(2)7-8-16-13-17(9-11-19(16)34)27(37)33-21-22(35)18-10-12-20(15(3)24(18)42-28(21)38)41-29-23(36)25(43-30(32)39)26(40-6)31(4,5)44-29/h7,9-13,23,25-26,29,34-36H,8H2,1-6H3,(H2,32,39)(H,33,37)/t23-,25+,26-,29-/m1/s1

1 reference

NOVOBIOCIN (English)

19 November 2016

2 references

inferred from InChIKey

MSBNK-Athens_Univ-AU116701

1 reference

MassBank accession ID

0 references

MSBNK-Athens_Univ-AU116702

0 references

MSBNK-Athens_Univ-AU116703

0 references

MSBNK-Athens_Univ-AU116704

0 references

MSBNK-Athens_Univ-AU116705

0 references

MSBNK-Athens_Univ-AU116706

0 references

MSBNK-Athens_Univ-AU116751

0 references

MSBNK-Athens_Univ-AU116752

0 references

MSBNK-Athens_Univ-AU116753

0 references

MSBNK-Athens_Univ-AU116754

0 references

MSBNK-Athens_Univ-AU116755

0 references

SPLASH

splash10-000i-0900000000-e321cd21925818d2156a

0 references

splash10-000i-0900000000-6425ec6e8bbb44075cf4

0 references

splash10-000i-0900000000-32fb8ff4ec7fde30b513

0 references

splash10-000i-0900000000-004f89ab3d920e8c5936

0 references

splash10-000j-0933000000-cd71bb412108d603ba2d

0 references

splash10-03di-0000009000-b1cde524a6fa9a8469fb

0 references

splash10-03di-0000449000-4b6598caa7dcff199d3c

0 references

splash10-0230-0005904000-5fe18777e8a9abd4250a

0 references

splash10-0a59-0096200000-4ea433cdc759c03b554d

0 references

splash10-0a4i-0091000000-912d33bd49e7c2686b5b

0 references

HSDB ID

7443

1 reference

Hazardous Substances Data Bank

28 October 2019

NOVOBIOCIN (English)

10 May 2021

2 references

Mapping file of InChIStrings, InChIKeys and DTXSIDs for the EPA CompTox Dashboard

DSSTOX compound identifier

0 references

1 reference

English

title

novobiocin (English)

ECHA Substance Infocard ID

19 November 2016

100.005.589

1 reference

ECHA Substance Infocard database

ECHA Substance Infocard ID

27 December 2018

Novobiocin (English)

CAS no.: 303-81-1 (English)

MeSH descriptor ID

D009675

subject named as

Novobiocin

0 references

MeSH concept ID

M0015020

0 references

MeSH tree code

D03.383.663.283.446.139.500

0 references

D03.633.100.150.446.139.500

0 references

0 references

1 reference

novobiocin (English)

19 November 2016

1 reference

Human Metabolome Database ID

HMDB0015185

2 references

based on heuristic

inferred from InChIKey

1 reference

novobiocin (English)

19 October 2016

2 references

English

title

novobiocin (English)

19 November 2016

NDF-RT ID

N0000147947

1 reference

novobiocin (English)

19 November 2016

0 references

1 reference

1 reference

https://docs.openalex.org/download-snapshot/snapshot-data-format

Novobiocin (English)

19 January 2016

0 references

1 reference

6 April 2020

1 reference

28 October 2013

Microsoft Academic ID

0 references

1 reference

26 January 2022

1 reference

1S14 (English)

19 October 2016

1 reference

1AJ6 (English)

19 October 2016

1 reference

3LPS (English)

19 October 2016

1 reference

1KIJ (English)

19 October 2016

1 reference

4URO (English)

19 October 2016

1 reference

4URN (English)

19 October 2016

1 reference

inferred by common MeSH mappings on source and on Wikidata

novobiocin (English)

19 November 2016

1 reference

UMLS 2023

25 May 2023

WordNet 3.1 Synset ID

03838949-n

1 reference