Deficiencies in DNA damage repair limit the function of haematopoietic stem cells with age (Q28505636)

24 January 2017

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31 December 2019

title

Deficiencies in DNA damage repair limit the function of haematopoietic stem cells with age (English)

2 references

24 January 2017

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Excision repair cross-complementing rodent repair deficiency, complementation group 2

31 December 2019

main subject

1 reference

X-ray repair complementing defective repair in Chinese hamster cells 5

GOA release 2020-03-11

1 reference

GOA release 2020-03-11

author

David Bryder

2

1 reference

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31 December 2019

Jun Seita

3

1 reference

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31 December 2019

6

Irving L Weissman

1 reference

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31 December 2019

5

Jan Hoeijmakers

2 references

24 January 2017

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31 December 2019

author name string

Andre Nussenzweig

4

2 references

24 January 2017

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31 December 2019

Derrick J Rossi

1

1 reference

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31 December 2019

language of work or name

English

0 references

publication date

1 June 2007

1 reference

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31 December 2019

2 references

24 January 2017

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31 December 2019

volume

447

2 references

24 January 2017

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31 December 2019

issue

7145

2 references

24 January 2017

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31 December 2019

page(s)

725-729

1 reference

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Does functional depletion of stem cells drive aging?

31 December 2019

cites work

1 reference

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7 January 2021

DNA repair defects in stem cell function and aging

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A mouse model for the basal transcription/DNA repair syndrome trichothiodystrophy

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Premature aging in mice deficient in DNA repair and transcription

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Telomere shortening and tumor formation by mouse cells lacking telomerase RNA

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Longevity, Stress Response, and Cancer in Aging Telomerase-Deficient Mice

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Requirement for Ku80 in growth and immunoglobulin V(D)J recombination

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7 January 2021

Hypersensitivity of Ku80-deficient cell lines and mice to DNA damage: the effects of ionizing radiation on growth, survival, and development

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7 January 2021

Cell intrinsic alterations underlie hematopoietic stem cell aging.

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7 January 2021

Age-associated characteristics of murine hematopoietic stem cells

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7 January 2021

The aging of hematopoietic stem cells

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Hematopoietic stem cells: the paradigmatic tissue-specific stem cell

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7 January 2021

Cytokine signals modulated via lipid rafts mimic niche signals and induce hibernation in hematopoietic stem cells

1 reference

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7 January 2021

Global analysis of proliferation and cell cycle gene expression in the regulation of hematopoietic stem and progenitor cell fates

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7 January 2021

DNA damage-dependent cell cycle checkpoints and genomic stability

1 reference

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7 January 2021

Telomerase is required to slow telomere shortening and extend replicative lifespan of HSCs during serial transplantation

1 reference

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7 January 2021

Long-term repopulating ability of telomerase-deficient murine hematopoietic stem cells

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7 January 2021

Cdkn1a deletion improves stem cell function and lifespan of mice with dysfunctional telomeres without accelerating cancer formation

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7 January 2021

The role of apoptosis in the regulation of hematopoietic stem cells: Overexpression of Bcl-2 increases both their number and repopulation potential

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7 January 2021

DNA double-stranded breaks induce histone H2AX phosphorylation on serine 139

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7 January 2021

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7 January 2021

Understanding the odd science of aging

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7 January 2021

Hematopoietic dysfunction in a mouse model for Fanconi anemia group D1

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7 January 2021

Repopulating defect of mismatch repair–deficient hematopoietic stem cells

1 reference

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7 January 2021

Reduced hematopoietic reserves in DNA interstrand crosslink repair-deficient Ercc1-/- mice

1 reference

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7 January 2021

Regulation of oxidative stress by ATM is required for self-renewal of haematopoietic stem cells

1 reference

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7 January 2021

Reactive oxygen species act through p38 MAPK to limit the lifespan of hematopoietic stem cells

1 reference

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7 January 2021

Cancer predisposition and hematopoietic failure in Rad50(S/S) mice

1 reference

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7 January 2021

The Rad50S allele promotes ATM-dependent DNA damage responses and suppresses ATM deficiency: implications for the Mre11 complex as a DNA damage sensor.

1 reference

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7 January 2021

Lnk negatively regulates self-renewal of hematopoietic stem cells by modifying thrombopoietin-mediated signal transduction

1 reference

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7 January 2021

DNA repair protein Ku80 suppresses chromosomal aberrations and malignant transformation

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7 January 2021

Essential role of mouse telomerase in highly proliferative organs

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7 January 2021

Haploinsufficiency of mTR results in defects in telomere elongation

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7 January 2021

Telomere shortening accompanies increased cell cycle activity during serial transplantation of hematopoietic stem cells

1 reference

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7 January 2021

Disease states associated with telomerase deficiency appear earlier in mice with short telomeres

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7 January 2021

Identifiers

DOI

10.1038/NATURE05862

2 references

Consolidated OpenCitations Corpus – April 2017

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:17554309%20AND%20SRC:MED&resulttype=core&format=json

Dimensions Publication ID

31 December 2019

1004325946

0 references

1 reference

Consolidated OpenCitations Corpus – April 2017

2 references

Consolidated OpenCitations Corpus – April 2017