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RB Leipzig vs. Manchester City odds, picks and predictions

Nathan Beighle
Sportsbook Wire

RB Leipzig welcomes Manchester City to Red Bull Arena Leipzig on Wednesday. Kickoff is set for 3 p.m. ET (CBS SPorts Network). Below, we preview Tipico Sportsbook's lines around the RB Leipzig vs. Manchester City odds, and make our best Champions League bets, picks and predictions.

This match, and the Inter vs. Porto match, are the final 1st leg Round of 16 battles for the UEFA Champions League. Second legs kick off March 2.

RB Leipzig sits 5th in the Bundesliga and has won 7 of 10 home games. They average 2.05 goals and allow 1.24 goals per game in league play. Leipzig finished 2nd in Group F behind Real Madrid. In their 6 group stage matches, they scored 13 goals and allowed 9.

Manchester City scored 14 and allowed 2 as they finished atop Group G with 4 wins and 2 draws. Their +12 goal differential was only beaten by Napoli (+14) and Bayern Munich (+16). City sits 2nd in the EPL this season and is 6-3-3 away from home.

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RB Leipzig vs. Manchester City odds

Provided by Tipico Sportsbook; access USA TODAY Sports Scores and Sports Betting Odds hub for a full list. Lines last updated at 12:13 a.m. ET.

  • Moneyline: RB Leipzig +320 (bet $100 to win $320) | Manchester City -117 (bet $117 to win $100) | Draw +280
  • Over/Under: 2.5 (O: -135 | U: +115)

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RB Leipzig vs. Manchester City picks and predictions

Prediction

Manchester City 3, RB Leipzig 1

Moneyline (ML)

PASS.

While the Arsenal onslaught in the EPL has overshadowed City's play, their offense has been elite, scoring 2.5 goals per game this season. They have won 5 of their last 7 games throughout all competitions and are clearly the more talented side.

However, in the group stage last season, they had fewer expected goals when taking on Leipzig on the road and ended up losing 2-1. While City will be a popular favorite, pass on the moneyline here. Red Bull Arena has been a difficult place to win this season, but betting against City also isn't a wise move.

Over/Under (O/U)

BET OVER 2.5 (-135).

In the 2 games between these teams last season, there were 12 goals scored, and in each game, both teams has more than 1 expected goal. On top of that, City's defense has taken a step back, averaging 1 goal per game allowed which doesn't compare favorably to the .68 they allowed per game last season.

The absence of M Kevin de Bruyne could be beneficial here as well with M Phil Foden potentially sliding in and producing a more offense-focused style of play. That said, Leipzig is averaging 2.05 goals per game which is similar to last season's 2.12. They scored 2 goals per game on City in 2 matchups.

Put it all together, and back the OVER 2.5 (-135).

Check out Pro Soccer Wire: For the American soccer fan, USA TODAY Sports Media Group's website provides a fresh look at the beautiful game.

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