Multiple myeloma is a malignant plasma cell disorder characterized by the overproduction of monoclonal proteins. The kidney is 1 of the major target organs of multiple myeloma. Most often, this is the result of the monoclonal proteins, which can injure the kidney via several mechanisms. In some cases, direct invasion by myeloma cells and/or bone marrow cells can also result in kidney injury. A kidney biopsy can help distinguish the various myeloma-related kidney diseases and aid in the treatment plan.
Keywords: Amyloidosis; Cast nephropathy; Kidney; MIDD; Multiple myeloma.
Copyright © 2014 National Kidney Foundation, Inc. Published by Elsevier Inc. All rights reserved.