Evolutionary dynamics and population stratification analysis of whole genomes of the cattle flu Influenza D virus reveal its high evolution rate, extensive diversification and global dissemination, stressing the need for targeted surveillance.

Multidrug-resistant Acinetobacter baumanniicultured for 8000 generations under either starvation or nutrient-rich conditions reveals significant genomic alterations and changes in virulence, primarily driven by insertion sequences and prophages.

The deubiquitinase USP24 stabilizes Beclin1 by decreasing its K48-linked ubiquitination. The interaction between USP24 and Beclin1 represents a key molecular mechanism that promotes autophagy related ferroptosis in HCC.

Standardized indices of obesity are associated with alterations in neural oscillatory activity and functional connectivity in brain regions supporting abstract reasoning and fluid intelligence in typically developing youth.

Computational tools and F0 null mutant analysis allow the identification of the maternal chromatin regulators Mcm3l, Mcm6l, and Npm2a in zebrafish embryogenesis, which are essential for DNA replication and cell division.

circMeta2 performs differential expression analysis for clustered circRNAs. Using this tool, the authors identify brain region-specific circRNA clusters in healthy controls, as well as their key dysregulations associated with Alzheimer’s Disease progression.

Sodium salicylate enhances endocannabinoid signaling, reducing GABAergic activity in the thalamic reticular nucleus. This increases gamma oscillations in the auditory cortex and prefrontal cortex, causing hyperacusis and anxiety-like behaviors.

The graph attention based automatic encoder utilizing contrastive learning effectively combines spatial location information and gene expression data from spatial transcriptomics for enhanced domain recognition capacity.

Offset responses to auditory click trains reveal temporal integration in the auditory cortex, introducing the ‘Neuronal Integrative Window’ concept and suggesting offset responses as potential biomarkers for assessing and monitoring brain health.

Single-cell RNA sequencing reveals key molecular characteristics of cranial neural crest cell-derived mesenchymal cells in teeth and antlers, laying foundation innovative therapeutic strategies for tissue regeneration

A study on African lions in Uganda’s Nile Delta shows wildlife tourism rangers, an often-forgotten group in the scientific process, deliver strong density estimates. The study also shows infrared camera traps are weak at detecting lions.

This Comment reviews a recent workshop that aimed at improving funding outcomes for consciousness science researchers. The most essential pieces of advice for early career consciousness scientists are summarized.

Light scattering, resulting from refractive index mismatch, is the primary factor limiting imaging depth in biological tissue. In a study recently published in Science¹, Ou et al. took an unconventional approach and employed highly absorbing molecules, such as food dye tartrazine, to increase the refractive index of water in the near-infrared wavelength range, which rendered tissue transparent in live mice.

Dr. Guifen Liu, now an Associate Professor at ZhangLab, Tongji University, began her research in epigenetic regulation using zebrafish as a model, first as a postdoctoral researcher and then as a research scientist. She established the zebrafish culturing system at the Department of Informatics, Tongji University, Shanghai, China. Dr. Qi Wang is an Assistant Professor at ZhangLab, Tongji University, and she is in charge of the cell culture part of the lab and has broad expertise in high-throughput experimental research on chromatin structure. They are the only two experimental biologists in a dry lab focusing on different research topics. At present, they are in the transition period from experimental scientists to computational scientists. Current Lab Members-Yong Zhang Lab (tongji.edu.cn).

In this Q&A, Brianna Bibel, also known as the Bumbling Biochemist, talks to the journal about how social media can be harnessed to relay scientific information to other researchers, while making it fun and accessible.

Conducting research at the interface of chemistry, microbiology and marine biology, Constanze Kuhlisch reports on challenges in science due to COVID and the situation in Israel, while preparing grants to start her own research group.