A phase 3 study shows that MDMA may be a promising treatment for PTSD, which will require a shift in how this drug is perceived.
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References
Mitchell, J. M. et al. Nat. Med. https://doi.org/10.1038/s41591-021-01336-3 (2021).
Freudenmann, R. W., Oxler, F. & Bernschneider-Reif, S. Addiction 101, 1241–1245 (2006).
Mithoefer, M. C. et al. J. Psychopharmacol. 25, 439–452 (2011).
Sessa, B. et al. J. Psychopharmacol. 35, 375–383 (2021).
Kuypers, K. P. et al. Psychopharmacology (Berl.) 235, 481–490 (2018).
Nardou, R. et al. Nature 569, 116–120 (2019).
Feduccia, A. A. & Mithoefer, M. C. Prog. Neuropsychopharmacol. Biol. Psychiatry 84, 221–228 (2018).
Carhart-Harris, R. L. et al. Int. J. Neuropsychopharmacol. 1, 527–540 (2013).
Bedi, G., Phan, K. L., Angstadt, M. & de Wit, H. Psychopharmacology (Berl.) 207, 73–83 (2009).
Carhart-Harris, R. L. et al. Biol. Psychiatry 78, 554–562 (2014).
Hysek, C. M. et al. Soc. Cogn. Affect. Neurosci. 9, 1645–1652 (2014).
Wardle, M. C. & de Wit, H. Psychopharmacology (Berl.) 231, 4219–4229 (2014).
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D.J.N. is a paid advisor to Awakn, a company with an interest in MDMA treatment research.
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Nutt, D.J., de Wit, H. Putting the MD back into MDMA. Nat Med 27, 950–951 (2021). https://doi.org/10.1038/s41591-021-01385-8
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DOI: https://doi.org/10.1038/s41591-021-01385-8