Although sphingolipids are vital cellular components, the path to their production is paved with toxic intermediates. Orm proteins allow cells to form these lipids without killing themselves in the process.
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Tafesse, F., Holthuis, J. A brake on lipid synthesis. Nature 463, 1028–1029 (2010). https://doi.org/10.1038/4631028a
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DOI: https://doi.org/10.1038/4631028a
