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Clarke and parkes error grid analysis of diabetic glucose models obtained with evolutionary computation

Published: 12 July 2014 Publication History

Abstract

Diabetes mellitus is a disease that affects to hundreds of millions of people worldwide. Maintaining a good control of the disease is critical to avoid severe long-term complications. In recent years, a lot of research has been made to improve the quality of life of the diabetic patient, especially in the automation of glucose level control. One of the main problems that arises in the (semi) automatic control of diabetes, is to obtain a model that explains the behavior of blood glucose levels with insulin, food intakes and other external factors, fitting the characteristics of each individual or patient. Recently, Grammatical Evolution (GE), has been proposed to solve this lack of models. A proposal based on GE was able to obtain customized models of five in-silico patient data with a mean percentage average error of 13.69%, modeling well also both hyper and hypoglycemic situations. In this paper we have extended the study of Error Grid Analysis (EGA) to prediction models in up to 8 in-silico patients. EGA is commonly used in Endocrinology to test the clinical significance of differences between measurements and real value of blood glucose, but has not been used before as a metric in obtention of glycemia models.

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  • (2020)Modelling and optimisation of treatment parameters in high-dose-rate mono brachytherapy for localised prostate carcinoma using a multilayer artificial neural network and a genetic algorithmComputers in Biology and Medicine10.1016/j.compbiomed.2020.104045126:COnline publication date: 1-Nov-2020
  • (2017)Personalized blood glucose prediction: A hybrid approach using grammatical evolution and physiological modelsPLOS ONE10.1371/journal.pone.018775412:11(e0187754)Online publication date: 7-Nov-2017

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cover image ACM Conferences
GECCO Comp '14: Proceedings of the Companion Publication of the 2014 Annual Conference on Genetic and Evolutionary Computation
July 2014
1524 pages
ISBN:9781450328814
DOI:10.1145/2598394
Permission to make digital or hard copies of all or part of this work for personal or classroom use is granted without fee provided that copies are not made or distributed for profit or commercial advantage and that copies bear this notice and the full citation on the first page. Copyrights for components of this work owned by others than ACM must be honored. Abstracting with credit is permitted. To copy otherwise, or republish, to post on servers or to redistribute to lists, requires prior specific permission and/or a fee. Request permissions from [email protected]

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Published: 12 July 2014

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Author Tags

  1. diabetes
  2. grammatical evolution
  3. modeling

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GECCO '14
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GECCO '14: Genetic and Evolutionary Computation Conference
July 12 - 16, 2014
BC, Vancouver, Canada

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GECCO Comp '14 Paper Acceptance Rate 180 of 544 submissions, 33%;
Overall Acceptance Rate 1,669 of 4,410 submissions, 38%

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View all
  • (2020)Modelling and optimisation of treatment parameters in high-dose-rate mono brachytherapy for localised prostate carcinoma using a multilayer artificial neural network and a genetic algorithmComputers in Biology and Medicine10.1016/j.compbiomed.2020.104045126:COnline publication date: 1-Nov-2020
  • (2017)Personalized blood glucose prediction: A hybrid approach using grammatical evolution and physiological modelsPLOS ONE10.1371/journal.pone.018775412:11(e0187754)Online publication date: 7-Nov-2017

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