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Business and Strategy developer

Imagine for a moment to sit for 10 days beside the person you care most. This person is lying on a bed waiting for doctors, who, given the really special case, are thinking IF and how to intervene. In those 10 days, most probably you will be thinking ‘how I can contribute to fix this’ and the only voice you hear in your head is telling you ‘I am useless’. Most probably the majority of us in the circle of his/her full life, despite the training, studies and job, soon or late will face someone close to be affected by though health conditions, which will manifest themselves quick or slow and will put ourself in front of a couple of questions: could I know that? Could I prevent that? Being side to side to someone with potential health conditions, and not only with manifested health conditions, makes each of us being always a care giver of our beloved. This is what happened to me, when a 39 years old girl, my wife, Germana, passed away because an aneurysm of an incredible size. The questions I asked myself were: - As a husband could I detect symptoms that maybe I did not considered as such?’ - Is there sex and gender bias that characterises this health condition? Could be this bias there from a care giver perspective? - How can I make out of this loss something useful to avoid that other people will live my same experience? This is how I was moved to contact Antonella and the Women Brain Project (WBP) team. A Team of volunteers active in creating awareness on sex and gender differentiation in neurological diseases with a special focus at that time on Alzheimer. My questions related to sex and gender differentiation in aneurysm found immediate attention. This is how this paper found its foundations. This is how I could accomplish one of my personal missions: create AWARENESS among all type of people (not only doctors or patients). All of us could have the role of a care giver even in apparently healthy situations. I would like to thank the WBP, now Women's Brain Foundation which enabled this project, and specially the people who took part to build this paper just published. From the deepest part of my soul thank you to Adelaide J. , Joanna Schaafsma , Dr. Risvin Naser , Julie N. , Simona Mellino, PhD , Maria Teresa Ferretti , Laura Castro-Aldrete Dr Antonella Santuccione Chadha

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Did you know that Saccular unruptured intracranial aneurysms (UIAs), are a silent threat, lurking within the walls of the intracranial arteries, with a higher risk in women than men? 🤔 The Women's Brain Foundation works relentlessly to understand the sex and gender characteristics impacting brain and mental health. Today, our dedicated scientists have published a critical piece on this topic: “Sex differences and possible applications of artificial intelligence in saccular unruptured intracranial aneurysms. A narrative review” The main learnings from this manuscript: 1) Saccular UIAs are more prevalent among females than males, in over 50-year-old patients, the female-to-male prevalence ratio of UIA gets as high as 2.2:1! 2) These sex differences might have a connection to estrogen hormones and their influences on reproductive aging, the anatomy of cerebral arteries, and inflammatory processes. 3) AI has not yet been used to address sex- and gender differences in this field. It would be extremely relevant to train AI to factor in sex- and gender differences in aneurysm development and manifestation, enhancing the accuracy of current UIA screening techniques. A heartfelt thanks to everyone who collaborated on this project; your contributions were incredibly valuable! ⭐ Adelaide J., Luca Gambini-Rossano, Dr. Ing., Joanna Schaafsma, Dr. Risvin Naser, Julie N., Simona Mellino, PhD, Maria Teresa Ferretti, Laura Castro-Aldrete, Dr Antonella Santuccione Chadha 🤝 Support our research in advancing brain and mental health : https://lnkd.in/eWsAwhTX #intracranialaneurysm #UIA #sexdifferences #estrogen #menopause #imaging #AI #Womensbrainfoundation

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Thank you for sharing your personal story. Wonderful to read how you pushed through the pain and channelled it into a purpose. Congratulations for achieving your mission.

Very insightful and a great achievement on your mission to drive awareness for the topic of aneurysms. Thank you for doing this, Germa would be very proud of you, Luca

Maria Teresa Ferretti

Neuroscience - Brain health- Gender Medicine - Consultant- TED-x Speaker - Scientific Writer -Alzheimer Advocate - Editor -Privat Dozent - FEAN

2mo

Luca thanks to you, it was a privilege working with you in this project

Kate Bristow

Partner & Strategy Director at My Brilliant Friend

2mo

Well done Luca!!!

Aglaia Masala-Girardi

Executive Assistant | Office Manager | Management Assistant

2mo

Complimenti Luca!!!

Eva Bottai, MBA

Unlock your career potential, get unstuck and have joy at work again | Career Strategist, Mentor, Coach | EGN Group Chair | visit my website: career-redesign.com

2mo

What a powerful message! Thank you for sharing it, and very sorry for your loss, Luca, I didn’t know. My condolences.

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