Wheeler Bio, Inc.’s Post

We at Wheeler Bio, Inc. are excited to announce our upcoming #webinar: "Modular CMC Development for Antibodies: Deploying a Purpose-Designed Path to Clinic" live on Xtalks Oct. 7th at 1pm ET! Register now to hear from our expert panel and get a detailed look at how Wheeler is changing the #CMC #development paradigm by aligning all priorities with program success through modular work packages, structured documentation support, as well as built-in accommodations and tools to support clients and the consultants that facilitate their CMC path. Plus, all attendees will gain access to an exclusive survey report with insights and data pertinent to those on the #preclinical and early #clinical #biologics pathway. Don't miss out! Follow the link below to learn more.

Come see us at BPI! The Wheeler Bio, Inc. team will be in Boston September 23rd - 26th for the 2024 BioProcess International conference. Stop by Booth 833 to meet with Stewart McNaull, Ken Meek, and Peter Rock to learn about our turnkey #antibody platform (Portable CMC®), our #domestic small batch #biologics manufacturing solutions, and how we are supporting the #ADC supply chain by providing intermediate manufacturing to innovators. Also, don't forget to attend Stewart's talk entitled "Deploying Purpose-Built CMC Development Modules for Predictability and Speed to IND" on September 25th at 2:50pm EDT! We can't wait to see you all in Boston! Reach out to schedule a meeting: https://lnkd.in/e2ZpBWJN

On the 23rd anniversary of the deadliest terror attack in U.S. history, we remember and pay our respects to the thousands of innocent civilians whose lives were taken, the hundreds of courageous first-responders that sacrificed everything to save their fellow citizens, and the families forever changed by this atrocity. While today serves as a painful reminder of the events that unfolded in 2001, we must work to shift our focus to celebrate the bravery, selflessness, and the indominable spirit of the heroes that were born from the chaos of 9/11. Just as the nation was brought together on 9/12/2001 through this tragedy, we hope that we can similarly set our differences aside and come together by remembering what binds us, instead of what separates us. #NeverForget

Since the #BIOSECURE Act was introduced in the U.S. House of Representatives at the beginning of this year, the speculation and concern over its potential impacts have sent shockwaves through the #biopharma industry. With emerging #biotechs comprising 80% of the investigational drug pipeline, 65% of these companies working with overseas #CDMOs, and 80% of all APIs consumed in the U.S. being manufactured overseas, the concerns surrounding the impact this may have on drug development and supply as a whole are apparent. These concerns highlight the dire necessity to not only build up #domestic manufacturing capacity in order to mitigate against potential drug shortages, as was seen in the first half of 2024, but also the imperative for emerging biotechs to reshore their manufacturing before potentially losing out on federal funding, threatening life-saving drug programs. In our latest blog, we take a look at the potential impacts of the BIOSECURE Act on emerging biotechs, the advantages of prioritizing domestic biologics manufacturing, and how this could particularly threaten access to small-scale production. To learn more about how Wheeler Bio, Inc. is deploying our purpose-built Portable CMC® platform to ameliorate these concerns and provide a rapid, flexible, and cost-effective path to the clinic, visit wheelerbio.com or reach out any time to [email protected] to speak with our team!

Congratulations to the New England Free Jacks® on their second, back-to-back MLR championship! We at Wheeler Bio, Inc. are proud to have been part of the Free Jacks' 2024 championship pursuit as sponsors but also as fans. The character, resilience, and commitment to excellence displayed by the team was inspiring to all that watched. We cannot wait to see what next season has in store as the sport continues to grow!

𝐖𝐡𝐲 𝐝𝐨𝐞𝐬 𝐭𝐡𝐞 𝐜𝐨𝐧𝐯𝐞𝐧𝐭𝐢𝐨𝐧𝐚𝐥 𝐂𝐃𝐌𝐎 𝐦𝐨𝐝𝐞𝐥 𝐧𝐞𝐞𝐝 𝐭𝐨 𝐛𝐞 𝐫𝐞𝐛𝐮𝐢𝐥𝐭? There is a fundamental mismatch between the needs of drug innovators and the services provided by conventional CDMOs. This ingrained misalignment is what led to the conception of Wheeler Bio, Inc. Considering venture-backed biotechs account for around 80% of all programs in the investigational drug pipeline, these companies require CDMO services that are flexible, efficient, and align with their goals for the success of their programs. At Wheeler, we recognized the scarcity of these attributes in the CDMO industry and the impact this has on the overall therapeutic pipeline. In order to solve these needs and thereby ensure more advanced therapeutics reach patients in need, we rebuilt the conventional CDMO model in favor of innovators through: ▶ 𝐈𝐧𝐭𝐞𝐠𝐫𝐚𝐭𝐞𝐝 𝐩𝐚𝐫𝐭𝐧𝐞𝐫𝐬𝐡𝐢𝐩 𝐦𝐨𝐝𝐞𝐥: Uniting specialists into a one-stop-shop, ameliorating the CRO-CDMO trench and building a clear path from Discovery to IND. ▶ 𝐌𝐨𝐝𝐮𝐥𝐚𝐫 𝐰𝐨𝐫𝐤 𝐩𝐚𝐜𝐤𝐚𝐠𝐞𝐬: Low-cost entry, no scope creep, access to early CMC data, and unmatched flexibility. ▶ 𝐓𝐮𝐫𝐧𝐤𝐞𝐲 𝐩𝐥𝐚𝐭𝐟𝐨𝐫𝐦: Greater speed, reduced risk, enhanced predictability, and an intense focus on antibody and antibody-like modalities. ▶ 𝐏𝐮𝐫𝐩𝐨𝐬𝐞 𝐛𝐮𝐢𝐥𝐭 𝐟𝐚𝐜𝐢𝐥𝐢𝐭𝐢𝐞𝐬: Right scale manufacturing, flexible ballroom suites, and state-of-the-art technologies. ▶ 𝐀𝐥𝐥-𝐢𝐧-𝐨𝐧𝐞 𝐩𝐫𝐢𝐜𝐢𝐧𝐠: Predictable cash burn, no surprise costs or budget creep. Check out our latest article below and reach out to [email protected] to learn more about how we are changing the CDMO paradigm! #Biotech #Biopharma #Antibody #Therapeutics

ICYMI: Wheeler Bio, Inc.'s CEO and Co-Founder Jesse McCool joined a panel with our partners at Charles River Laboratories to discuss how our integrated partnership model is streamlining the path to IND by uniting specialists in their respective fields into a one-stop-shop from early discovery to FiH. Check out the video to learn more about how Wheeler is applying our purpose-built CMC development and right-size manufacturing platform (Portable CMC®) to solve translational challenges for early-stage biotechs! #CMC #Pharma #Biologics #Antibody #Therapeutics