Viltis’ Post

Human organ transplantation is indeed a fascinating and critical field of study. The ability to replace damaged or failing organs with healthy ones has transformed countless lives 🫀🧠🫁. From heart transplants to kidney donations, these medical procedures have given hope to patients and their families 🫀🧠🫁.   On Medical Series-II Part 4   Judgments   Human organ transplant is a medical procedure in which an organ is removed from one body and placed in the body of a recipient, to replace a damaged or missing organ. The organ may come from a living donor or a donor who has died. Organ transplantation can save lives or restore essential functions where no alternatives of comparable effectiveness exist. Some of the organs that have been successfully transplanted include the heart, kidneys, liver, lungs, pancreas, intestine, thymus and uterus. Tissues such as bones, tendons, cornea, skin, heart valves, nerves and veins can also be transplanted. However, organ transplantation also raises a number of bioethical issues, such as the definition of death, consent, payment, trafficking, tourism, and allocation of organs. There are also challenges in ensuring the safety, quality, efficacy and equity of donation and transplantation of human cells, tissues and organs. Organ transplantation is one of the most challenging and complex areas of modern medicine. It requires the collaboration of many professionals, institutions and organizations, as well as the support of the public and the patients.     #organtransplant #medicaleducation #medicalcourses #LinkedInLegal #linkedinlearning

I’m glad to hear that you have written a research article on human organ transplant. It sounds like a very interesting and important topic. 🙌   On Medical Series-II Part 1   Human organ transplant is a medical procedure in which an organ is removed from one body and placed in the body of a recipient, to replace a damaged or missing organ. The organ may come from a living donor or a donor who has died. Organ transplantation can save lives or restore essential functions where no alternatives of comparable effectiveness exist. Some of the organs that have been successfully transplanted include the heart, kidneys, liver, lungs, pancreas, intestine, thymus and uterus. Tissues such as bones, tendons, cornea, skin, heart valves, nerves and veins can also be transplanted. However, organ transplantation also raises a number of bioethical issues, such as the definition of death, consent, payment, trafficking, tourism, and allocation of organs. There are also challenges in ensuring the safety, quality, efficacy and equity of donation and transplantation of human cells, tissues and organs. Organ transplantation is one of the most challenging and complex areas of modern medicine. It requires the collaboration of many professionals, institutions and organizations, as well as the support of the public and the patients🫀🧠🫁. Human organ transplant #organtransplant #medicaleducation #medicalcourses #LinkedInLegal #linkedinlearning

I’m glad to hear that you have written a research article on human organ transplant. It sounds like a very interesting and important topic. 🙌   On Medical Series-II Part 3 🫀🧠🫁.   Forms required for organ donation and transplant    Human organ transplant is a medical procedure in which an organ is removed from one body and placed in the body of a recipient, to replace a damaged or missing organ. The organ may come from a living donor or a donor who has died. Organ transplantation can save lives or restore essential functions where no alternatives of comparable effectiveness exist. Some of the organs that have been successfully transplanted include the heart, kidneys, liver, lungs, pancreas, intestine, thymus and uterus. Tissues such as bones, tendons, cornea, skin, heart valves, nerves and veins can also be transplanted. However, organ transplantation also raises a number of bioethical issues, such as the definition of death, consent, payment, trafficking, tourism, and allocation of organs. There are also challenges in ensuring the safety, quality, efficacy and equity of donation and transplantation of human cells, tissues and organs. Organ transplantation is one of the most challenging and complex areas of modern medicine. It requires the collaboration of many professionals, institutions and organizations, as well as the support of the public and the patients 🫀🧠🫁.     #organtransplant #medicaleducation #medicalcourses #LinkedInLegal #linkedinlearning

Happy to share my research article on human organ transplant. On Medical Series-II Part 2   Procedure for human transplant Human organ transplant is a medical procedure in which an organ is removed from one body and placed in the body of a recipient, to replace a damaged or missing organ. The organ may come from a living donor or a donor who has died. Organ transplantation can save lives or restore essential functions where no alternatives of comparable effectiveness exist. Some of the organs that have been successfully transplanted include the heart, kidneys, liver, lungs, pancreas, intestine, thymus and uterus. Tissues such as bones, tendons, cornea, skin, heart valves, nerves and veins can also be transplanted. However, organ transplantation also raises a number of bioethical issues, such as the definition of death, consent, payment, trafficking, tourism, and allocation of organs. There are also challenges in ensuring the safety, quality, efficacy and equity of donation and transplantation of human cells, tissues and organs. Organ transplantation is one of the most challenging and complex areas of modern medicine. It requires the collaboration of many professionals, institutions and organizations, as well as the support of the public and the patients.   #organtransplant #medicaleducation #medicalcourses #LinkedInLegal #linkedinlearning

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Urgent Need for Reform in Organ Procurement: Ensuring Accountability and Saving Lives The organ procurement system in the USA faces significant challenges that undermine its effectiveness. Organ Procurement Organizations play a critical role but often fall short, leading to inefficiencies and missed opportunities to save lives. Thousands of viable organs are discarded annually due to mismanagement, highlighting the need for comprehensive reform and increased oversight. Recent studies illustrate the system's shortcomings: 💔 2019 JAMA Surgery study found over 3,500 kidneys were discarded in 2016 alone, despite many being viable for transplantation. This represents a significant loss of life-saving opportunities. 🏥 2020 report by the U.S. Department of Health and Human Services revealed only 23 of 58 OPOs met government performance standards, indicating widespread inefficiencies. 🌍 Data from the UNOS shows significant regional disparities in donation rates and transplant outcomes, reflecting inequities in access and care quality. To address these issues, Congress must implement stricter oversight and accountability for OPOs. Key policy reforms should include: 📋 Establishing a robust framework for monitoring OPO performance, with clear success metrics and penalties for non-compliance, including independent audits and regular reporting. ⚖️ Imposing stringent penalties on OPOs failing to meet care and efficiency standards, incentivizing immediate improvements. 🧬 Mandating advanced technologies and protocols for assessing organ viability to reduce the rate of discarded organs. This includes improved preservation techniques and real-time monitoring systems. 📊 Requiring detailed reporting on all aspects of organ procurement, including reasons for discarded organs, to identify systemic issues and develop targeted solutions. Public awareness is crucial for driving change. Educational campaigns can inform the public and policymakers about the need for reform and the potential benefits of a more efficient system. Addressing these issues will create a more #equitable and effective organ procurement system that serves patients' needs. Implementing #policy changes and fostering a culture of continuous improvement and accountability within #OPOs is essential. The ultimate goal is to ensure every viable organ reaches a patient in need, maximizing the life-saving potential of organ transplantation. Reforming the organ procurement system in the USA is urgent and necessary. By pushing for stronger oversight, better accountability, and advanced technologies to confirm organ viability, we can save more lives and create a fairer, more efficient system. #Congress must take decisive action, and all stakeholders must commit to the necessary changes. #OrganDonation #HealthcareReform #OPOAccountability #TransplantSurgery #SaveLives #PolicyReform #MedicalEthics #HealthcareImprovement #Grassroots #AdvocacyMovement

Unlike the old adage that the fastest way to be a millionaire is to be a billionaire opening an airline 😅 - TransMedics, Inc. may have found that the only way to make money by owning an airplane fleet: couple it with organ transplant technology. When we talk about organ transplantation, most investors feel that it is a medical field that was revolutionized decades ago, with donor availability seen as the primary constraint. First, one need not forget the scale of the need: Organ failure is both common and lethal, accounting for 5.2% of all emergency department contacts, and one-year all-cause mortality is 29.8% among organ failure patients. Waiting lists for organ transplants have known only one way: "up and to the right" Second, a bigger challenge is the inability to keep organs viable for longer periods. 40 to 80% of organs, depending on the type, become non-viable within hours after the donor's death and must be discarded... straight into the bin... That's where Transmedics intervenes, and it is literally life-saving. Transmedics have a warm perfusion system for the heart, liver, and lung to maintain the organs viable long enough for the donor to be in New York and the operation to take place in Los Angeles. And to bridge that distance quickly, they invested in an airplane fleet. This news tanked the stock almost 60% last year! Well, it is supposed to be the fastest way to lose money 😂 . But 💲 results speak for themselves: The company reported its best year and its best quarter yet, with Q1 net revenue reaching $96.9mn (vs. consensus estimates of $83.8mn). All margins improved, leading to a significant earnings per share (EPS) beat of $0.35, compared to the expected -$0.02. TransMedics has raised its full-year revenue guidance to between $390-400mn, up from the previous forecast of $360-370mn and well above the consensus of $367mn. This represents over 60% year-over-year growth. No wonder we consider this position one of the top positions in our Bionics strategy. ----- 🔗 https://lnkd.in/eapQrhkf The article provides more information on competition, market size, and fundamentals. #bionics #investing #healthcare atonra

Promising advancements in the healthcare industry! 🌟 Transmedics is leading the way in the $8 billion U.S. organ transplant market, saving lives and extending organ survival with their groundbreaking solutions. With a track record of fulfilling promises, we're confident they'll surpass expectations by achieving their 2027 goal of 10,000 transplants. Transmedics remains a cornerstone of our Bionics strategy. Read the entire article of our specialist Romain Bodinier, Ph.D ⬇⬇⬇⬇⬇⬇⬇ 💡 #Transmedics #HealthcareInnovation #OrganTransplants #BionicsStrategy

Organ Recovery Systems is pursuing regulatory clearance for its second LifePort product, this time for liver preservation—the LifePort Liver Transporter (see figure below). “We’re a very mature company for kidney, but kind of a start-up for liver,” says CEO David Kravitz , but adds that the company has “excellent clinical data and very functional machines.” The pivotal clinical study for the liver device’s FDA regulatory submission is now complete, and FDA granted ongoing enrollment of patients in a Continued Access study that is currently in progress pending final FDA review, with more than 125 patients transplanted. Surgeons involved in the Continued Access study have reported “remarkable outcomes” when recovering organs from expanded criteria donors that wouldn’t otherwise have been considered for donation, with transplant outcomes equaling or exceeding those from standard criteria donors. Kravitz notes, “One of the biggest differences between liver and kidney transplantation is that the liver patient on the waiting list is on death’s doorstep and there’s no second chance. The kidney patient can often remain on dialysis and wait for another kidney.” Read more from "Newcomers and Incumbents Push for Evolution of Organ Transplant Market" here: https://bit.ly/3U6VstW #medtech #medicaldevices #fdaregulatory #livercare #livertransplant

VESPER 5-year survival analysis: 1) ddMVAC is equal to GC in perioperative chemotherapy in MIBC in ITT population 2) in the neoadjuvant subgroup, ddMVAC has better 5 year OS (HR 0.71) and longer time to death (HR 0.55) compared to GC The raised question is: Why the urology oncology community doesn’t feel comfortable to change practice to ddMVAC instead of GC and the real world practice is still GC in all settings ALTHOUGH, most of the guidelines and RCTs suggested its benefits in Neoadjuvant setting ? 🧐 Possible explanations: 1) The similar results between both regimens in adjuvant and metastatic settings gave confidence and comfortability to carry on what we are familiar with (GC) 2) Most of bladder patients are old age with comrbidities and hardly tolerate GC, so giving more toxic regimen is very challenging 3) The dilemma of “is subgroup analysis could be practice changing ?” Or “to change the practice it should be the results of ITT population” However, I think in view of this recent mature data we should reconsider to change Let’s start with the most fit patients,and Build confidence and better experience with ddMVAC in our real practice 💪🏽 #ddMVACinNAC