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“Geneis Summer Talks” continues at full speed. In our second session, Dr. Berrin Monteleone, who is the head of the Genetic Cancer Department of New York University Hospital, presented us valuable information about cancer protection and early diagnosis. Dr. Monteleone drew attention to the importance of detection of genetic risks and personalized health approaches, and it was emphasized that especially genetic tests play a critical role in predicting the risk of cancer and that the quality of life could be improved by early diagnosis. Do not miss our livestream of our third session of the “Geneis Summer Talks” where we will be talking about “Reverse Aging” tomorrow with Dr. M. Bülent Kahyaoğlu, who specializes in dementia, Alzheimer’s disease, cerebrovascular diseases, headaches and migraines, epilepsy, movement disorders, and neuromuscular diseases. If you have questions, please write in the comments and we will answer them live! You can watch the full video on our Instagram account: https://lnkd.in/drd7y2U4

The high prevalence of sleep problems and its link with mortality warrants routine screening. Our novel predictive model using a machine learning approach offers clinically important insights for the early detection of comorbid insomnia and intervention in breast cancer survivors. #insomnia #breastcancer #japan

One of the first times a doctor recognized that inflammation might cause depression was in the late '80s when patients with melanoma were given an immunotherapeutic proinflammatory cytokine called interferon-alpha. Emory University psychiatrist Dr. Andrew Miller recalls the first time an oncologist colleague discussed this observation with him. He recalls that one patient, in particular, revealed that she lost their interest in life, "I'm even starting to think, you know, what's it all worth?" Were these feelings caused by the cancer diagnosis or the proinflammatory cytokine? One clue suggests it was the immunotherapy, because "if you pretreated people [with an antidepressant before receiving the inflammatory cytokine], you could really, really reduce the depression." Fast-forward 30 years into the future and we are still missing the appropriate (longitudinal) studies that can help researchers assess correlation vs causation. However, we at the Brain Inflammation Collaborative are trying to change that. Learn more by signing up to our newsletter 👉 https://lnkd.in/g9q6-nik Join our mission by sharing this content! #depression #immunopsychiatry #braininflammation Quote source: https://lnkd.in/gbXtexkX

Our mission is to help create molecules that will improve human health. On #WorldHealthDay, we highlight some of the small molecules we developed and discovered with our partners. From treating rare disorders to tackling cancer, infectious diseases, diabetes, neurodegeneration, and many more, we are committed to scientific innovations to bring molecules closer to the clinic. Learn more: https://lnkd.in/eB99dcGi Highlighted molecules: - sodium channel modulator (epilepsy) - ERa degrader (breast cancer) - ATAD2 inhibitor - molecular glue (cancer) - PRC2 modulator (blood disorder) - CXCR7 modulator (hear failure) - PINK1 activator (neurodegeneration) - NLRP3 inhibitor (inflammation) - FOXO1 inhibitor (diabetes) - sEH inhibitor (cardiovascular disease) - WDR91 inhibitor (virology) - LpxA inhibitor (infectious disease) - Mcl-1 inhibitor (cancer) - HAO1 inhibitor (rare disease) - PAR2 antagonist (neurology) #WorldHealthDay #BetterWorld #Medicines #Innovation #DrugDiscovery

June 8 is World Brain Tumor Day, an International Day of Commemoration initiated by the “Deutsche Hirntumorhilfe eV” (German Brain Tumor Association) in 2000 as a tribute to all patients with brain tumors and their families. This day aims to raise awareness among patients, their families, and the community about the seriousness, impact, early detection, and prevention of brain tumors. Brain tumors are the abnormal growth of cells in the brain that may be cancerous (malignant) or noncancerous (benign). Malignant brain tumors can be classified as primary, arising from the brain itself, or secondary, having metastasized from cancers elsewhere in the body. Regardless of the type, brain tumors can cause various neurological symptoms (headache, nausea, visual disturbances, paralysis, and facial numbness) depending on their location, size, and growth rate. According to the World Health Organization (WHO), brain tumors account for approximately 2% of all cancers in adults and 1.9% of all cancers in children. It is one of the most fatal diseases affecting adults and children of both sexes. Its incidence varies regionally, with higher rates reported in developed countries. The World Brain Tumor Day will focus on raising awareness about brain tumors and the importance of family support, as well as promoting research. Ongoing research is essential to improve treatment efficacy and quality of life of patients with brain tumors. Brain tumors, like many other diseases, can be associated with misconceptions and stigma. One of the goals of World Brain Tumor Day is to strengthen patients’ rights to reduce stigma. Reference： https://lnkd.in/gwYGwE2h https://lnkd.in/gAGW8HGY #WorldBrainTumorDay #BrainTumor　#BrainTumorAwareness #SupportPatients

Being sedentary has been linked to having extra pounds. And large studies have consistently shown that higher levels of body fat can spike your cancer risk. Chronic local inflammation from this fat can lead to cancer-causing DNA damage over time, according to the National Cancer Institute. Plus, a surplus of fat cells eventually produce hormones that lead to cell proliferation, a process that causes your cells to grow and divide rapidly. Your brain health suffers when you lounge for too long: Older adults who are sedentary may be just as likely to develop dementia as people who are genetically predisposed to the condition, recent research shows. Exactly how much activity you might need to get these effects still need to be teased out and may be different for men and women. For now, aim for at least the recommended 150 minutes a week of activity that gets your heart rate up.

🌟 Exciting News 🌟 I am thrilled to announce the publication of our latest research article on meta-analysis examined the "effectiveness of exercise interventions in reducing fatigue and depression among women undergoing chemotherapy for breast cancer". The results showed that exercise can substantially reduce fatigue level a common side effect of chemotherapy. Although depression did not significantly change , this study highlights the positive impact of exercise on mental health outcomes. The control group also experienced decreased quality of life , emphasizing the importance of incorporating exercise interventions to improve overall well-being during breast cancer treatment. In addition to primary outcomes, the study revealed that exercise positively affected secondary aspects such as cognitive fatigue, social function, physical function, constipation, and dyspnoea. 📄Read the full article here https://lnkd.in/ddpkXyY8 #Reaserach #oncology #BreastCancer #medicalResearch #Excercise #Fatigue #Depression #AdvanceBreastCancer #ScienceDirect #Publication #HealthCare #MedicalScience

Sleep duration may increase risks of several types of cancer ! There has been emerging evidences proving above statement. Short sleep duration has been associated with a greater risk of developing breast cancer colorectal cancer and prostate. Women with longer sleep duration ( > 9 hours /night) have been shown to have decreased risk of breast cancer . Epidemiological studies have reported a significantly increased risk of development of malignancies , including breast colon,prostate and endometrial cancer in night shift workers Nocturnal melatonin suppression due to decreased sleep duration or light exposure at night ( in case of shift worker) may promote cancer cell development and growth . Have you been aware of such kind of possibilities? #healthiswealth

Hats off to Gabriel and the Miller Lab for their diligent research on #neuromyelitis#optica, published in the prestigious Brain Journal. This work holds promise for future treatments, marking a significant step forward in our understanding. Your dedication and efforts are truly commendable. Well done! 👏 #MedicalResearch #TeamEffort #HealthcareInnovation