Metrohm’s Post

The ability to resolve multiple ionic species and polar analytes simultaneously, the excellent sensitivity when coupled to other methods, the high degree of automation possibilities – these aspects make ion chromatography (IC) ideal for routine quality control of drugs and pharmaceutical products.🧪👩🔬 In many cases, IC has been qualified for US Pharmacopeia standards, making it a vital tool in this field. If you'd like to know more about the potential of IC for pharmaceutical analysis, read our article 𝐀𝐝𝐯𝐚𝐧𝐜𝐢𝐧𝐠 𝐏𝐡𝐚𝐫𝐦𝐚𝐜𝐞𝐮𝐭𝐢𝐜𝐚𝐥 𝐀𝐧𝐚𝐥𝐲𝐬𝐢𝐬 𝐰𝐢𝐭𝐡 𝐈𝐨𝐧 𝐂𝐡𝐫𝐨𝐦𝐚𝐭𝐨𝐠𝐫𝐚𝐩𝐡𝐲 on LCGC International: https://lnkd.in/e2ARs_hU #MetrohmANZ #pharmaceutical #pharmaceuticalqualitycontrol #pharmaceuticalanalysis

Need to resolve multiple ionic species and polar analytes simultaneously…

Advancing Pharmaceutical Analysis with Ion Chromatography Ion chromatography (IC) is becoming increasingly important for pharmaceutical applications. According to Elke Süss of Metrohm, in many cases, IC has been qualified for US Pharmacopeia standards, making it a vital tool in this field. Link: https://lnkd.in/e2ARs_hU

𝗖𝗹𝗼𝘀𝗲𝗿 𝘁𝗼 𝘁𝗵𝗲 𝗙𝗼𝗿𝗺𝘂𝗹𝗮𝘁𝗼𝗿 (𝗖𝟮𝗙) – 𝗔 𝗖𝗲𝗻𝘁𝗲𝗿 𝗼𝗳 𝗘𝘅𝗰𝗲𝗹𝗹𝗲𝗻𝗰𝗲 𝗯𝘆 𝗗𝗙𝗘 𝗣𝗵𝗮𝗿𝗺𝗮 The new DFE Pharma Center of Excellence “Closer to the Formulator” (C2F) by DFE Pharma helps pharmaceutical companies to shorten the time from a concept to a finished commercial product through expertise in all phases of pharmaceutical development. The services offered by this new stateof-the-art facility, are mainly focused on Oral Solid Dosage (OSD) forms, comprising all types of pre-registration work including development, intermediate scale-up, and technology transfer. #pharmaceutical #excipients

𝗖𝗹𝗼𝘀𝗲𝗿 𝘁𝗼 𝘁𝗵𝗲 𝗙𝗼𝗿𝗺𝘂𝗹𝗮𝘁𝗼𝗿 (𝗖𝟮𝗙) – 𝗔 𝗖𝗲𝗻𝘁𝗲𝗿 𝗼𝗳 𝗘𝘅𝗰𝗲𝗹𝗹𝗲𝗻𝗰𝗲 𝗯𝘆 𝗗𝗙𝗘 𝗣𝗵𝗮𝗿𝗺𝗮 The new DFE Pharma Center of Excellence “Closer to the Formulator” (C2F) by DFE Pharma helps pharmaceutical companies to shorten the time from a concept to a finished commercial product through expertise in all phases of pharmaceutical development. The services offered by this new stateof-the-art facility, are mainly focused on Oral Solid Dosage (OSD) forms, comprising all types of pre-registration work including development, intermediate scale-up, and technology transfer. https://lnkd.in/e_tgzHpW #pharmaceutical #excipients

𝗧𝗵𝗲 𝗶𝗺𝗽𝗼𝗿𝘁𝗮𝗻𝗰𝗲 𝗼𝗳 𝗘𝘅𝗰𝗶𝗽𝗶𝗲𝗻𝘁 𝘀𝗲𝗹𝗲𝗰𝘁𝗶𝗼𝗻 𝗳𝗼𝗿 𝗺𝗼𝗱𝗶𝗳𝗶𝗲𝗱 𝗿𝗲𝗹𝗲𝗮𝘀𝗲 𝗳𝗼𝗿𝗺𝘂𝗹𝗮𝘁𝗶𝗼𝗻𝘀 The oral route is the main acceptable route, which offers more patient compliance and cost-effective manufacturing processes. Pharmaceutical dosage forms may be developed in which drug release characteristics with respect to time and/or location have in some way been modified compared with conventional dosage forms. These kind of modifications may have several objectives, such as maintaining therapeutic activity for an extended time (better patient compliance), reducing toxic effects, protecting active substances against degradation due to low pH, targeting the active substance to a predefined segment of the gastrointestinal tract for local treatment and product life cycle management for products that are near patent expiry. Thus, modified-release applications continue to be an important development strategy for the global pharmaceutical industry. However, apart from the advantages of modified-release dosage forms, there are numerous challenges in their development. Aqueous solubility, selective stability in the gastrointestinal tract, absorption window of the active ingredients and dose dumping are some of the challenges in the development of modified-release dosage forms. Learn more here: https://lnkd.in/eznvJcmZ #excipients MEGGLE Excipients PharmaExcipients.com

Monitoring nitrite impurities in pharmaceutical products and raw materials can be part of a control strategy for #nitrosamines. Ion chromatography (IC) is well suited for the analysis of trace amounts of nitrite. Find out more and download our free Application Notes here: https://lnkd.in/eb8tEND6 #metrohm #ionchromatography #nitrite #nitrosamine #pharmaceuticals #pharmaceuticalindustry #pharmaceuticalmanufacturing #rawmaterials

Drug products contain an active pharmaceutical ingredient (API) and other inactive ingredients. The purpose of the latter is to optimize the drug’s performance. 𝗧𝗵𝗶𝘀 𝗶𝘀 𝘄𝗵𝘆 𝗶𝘁'𝘀 𝘃𝗲𝗿𝘆 𝗶𝗺𝗽𝗼𝗿𝘁𝗮𝗻𝘁 𝘁𝗼 𝘃𝗲𝗿𝗶𝗳𝘆 𝘁𝗵𝗲 𝗾𝘂𝗮𝗹𝗶𝘁𝘆 𝗮𝗻𝗱 𝘀𝗮𝗳𝗲𝘁𝘆 𝗼𝗳 𝘁𝗵𝗲 𝗳𝗶𝗻𝗮𝗹 𝗽𝗿𝗼𝗱𝘂𝗰𝘁 𝗯𝘆 𝗱𝗲𝘁𝗲𝗿𝗺𝗶𝗻𝗶𝗻𝗴 𝘁𝗵𝗲 𝗮𝗰𝘁𝗶𝘃𝗲 𝗮𝗻𝗱 𝗶𝗻𝗮𝗰𝘁𝗶𝘃𝗲 𝗶𝗻𝗴𝗿𝗲𝗱𝗶𝗲𝗻𝘁𝘀. Read more: https://lnkd.in/dKpy4J3F #Pharma #PharmaIndustry #DrugManufacturing

Cleaning Validation in Pharmaceutical Industry : A Quick Guide https://lnkd.in/gm7qdNsn #Cleaning #Pharma #Pharmaceutical #Cleaningvalidation

Drug products contain an active pharmaceutical ingredient (API) and other inactive ingredients. The purpose of the latter is to optimize the drug’s performance. 𝗧𝗵𝗶𝘀 𝗶𝘀 𝘄𝗵𝘆 𝗶𝘁'𝘀 𝘃𝗲𝗿𝘆 𝗶𝗺𝗽𝗼𝗿𝘁𝗮𝗻𝘁 𝘁𝗼 𝘃𝗲𝗿𝗶𝗳𝘆 𝘁𝗵𝗲 𝗾𝘂𝗮𝗹𝗶𝘁𝘆 𝗮𝗻𝗱 𝘀𝗮𝗳𝗲𝘁𝘆 𝗼𝗳 𝘁𝗵𝗲 𝗳𝗶𝗻𝗮𝗹 𝗽𝗿𝗼𝗱𝘂𝗰𝘁 𝗯𝘆 𝗱𝗲𝘁𝗲𝗿𝗺𝗶𝗻𝗶𝗻𝗴 𝘁𝗵𝗲 𝗮𝗰𝘁𝗶𝘃𝗲 𝗮𝗻𝗱 𝗶𝗻𝗮𝗰𝘁𝗶𝘃𝗲 𝗶𝗻𝗴𝗿𝗲𝗱𝗶𝗲𝗻𝘁𝘀. Read more: https://lnkd.in/dp-WjaSn #Pharma #PharmaIndustry #DrugManufacturing