Lifespan.io News Outlet’s Post

“The concept of Environmental Enrichment was first studied by Canadian psychologist Donald O. Hebb in 1947, in an experiment with lab mice. Further on in 1960, American neuroscientist Marian Cleeves Diamond advanced Hebb’s notion of environmental enrichment and became one of the first to demonstrate that the brain changes through experiences and improves with enrichment, a process now known as neuroplasticity. Diamond, along with American psychologist Mark Rosenzweig, further advanced the study of environmental enrichment at the University of California, Berkeley, when they compared the brains of mice in enriched cages, regular cages, and impoverished environments.   They found that the brains of mice who grew up in enriched environments had better enzyme cholinesterase activity and increased cerebral cortex volume, and that they formed thicker cerebral cortices containing 25 percent more synapses, a process of renewal known as synaptogenesis. The cerebral cortices, the outer portion of the brain, of the enriched environment mice also grew by 6 percent compared to those of the mice in regular cages, while the cerebral cortices of the mice in impoverished spaces actually shrank. The mice in the enriched environments were also more visibly active and curious. This pioneering research proved that the brain can rewire itself and create new pathways as a result of environments we design.” Tye Farrow giving the keynote speech at Texas Tech University. More at www.causehealth.org   #causehealth #enrichedenvironments #architecture #healthdesign #salutogenesis

I am excited and proud to share that our article "The academic impact of paediatric research agendas: a descriptive analysis" has been published in BMC Research Involvement and Engagement. Research agendas are developed to address the mismatch between research questions prioritized by patients and those researched by researchers. Despite this effort, little is known about whether these priorities are elaborated upon In this paper, we describe the development of our tool, which is designed to assess whether the priorities of research agendas are being addressed. We examined 31 pediatric research agendas, analyzing whether the stated priorities were being addressed, to evaluate the academic impact of these agendas. Curious? Read the full article here: https://rdcu.be/dUvRs Together with my valued team Malou Luchtenberg, Els Maeckelberghe en Eduard Verhagen.

In our most recent educational webinar, Dr. Thomas PREVOT of the University of Toronto, shared insights into a method developed by his research group to alleviate stress and reactivity in research mice. While numerous studies have highlighted the amiable nature of laboratory rats during interactions with experimenters and caregivers, mice often face the challenge of being perceived as difficult to handle, unpredictable, and resistant to acclimating to human interactions. If you missed this episode, it’s not too late! Learn more and tune into the on-demand recording: https://bit.ly/42U6fKQ

🌟 Join SciLifeLab Science Summit on Spatial Biology and discover groundbreaking spatial omics techniques 🌟 Spatial Biology is revolutionizing life sciences through advances in Spatial Omics technologies. This summit will showcase the cutting-edge capabilities at SciLifeLab and highlight pioneering research addressing various life science areas. 🏢 Where? Uppsala Konsert & Kongress 📅 When? October 1st 📍 Registration and Poster Submission Deadline: September 13, 2024. More info & registration ➡ https://lnkd.in/gu9cADBp ♻️ Repost to spread the word! --- 🌍 SciLifeLab Planetary Biology Capability 🌍 We aim to connect and empower a multidisciplinary research community to tackle crucial challenges in ecology, conservation, evolution, and biogeochemistry. By leveraging SciLifeLab's comprehensive technology portfolio and resources, we aim to accelerate and support research from ecosystem to planetary scales. Follow us to stay updated on our latest research and initiatives! #Biodiversity #Research #Ecology #Evolution #Conservation

The idea of humans sharing commonalities with the sea lamprey might raise eyebrows, but a groundbreaking study by the Stowers Institute for Medical Research, published in Nature Communications, is flipping conventional wisdom on its head. Discover how this research is rewriting evolutionary narratives at https://amcen.co/3Tg7Oj9. Learn more about the connection between American Century and the Stowers Institute for Medical Research at https://amcen.co/4c3xR4c. #EvolutionaryInsights #ScienceNews #ResearchDiscovery

What if the secret to a youthful brain was as simple as a cetain metabolic environment which allowed neurone, oligodendrocyte, microglia and astrocyte to play together (share and provide nutrition for one another) - rather than to argue (compete for a nutrient which had a habit of either over-exposing or starving the cells - actually several times each day - blood glucose control is enforced in the state of hepatic ketones/gut biome derived SCFAs). Ketone + Butyrate/Propionate leading to Lactate. The relationship between neuro and immunology - between increased neural firing rate (through metabolic state) and activation of the immune system? And similarly quiescence of the brain and calming of the immune system. eg 'Excitotoxicity, neuroinflammation and oxidant stress as molecular bases of epileptogenesis and epilepsy-derived neurodegeneration' however excitotoxicity more generally through protein/carb consumption. Solution protein x carb -> soluble fibre x fat consumption vegan, natural particularly Greek olive oil, nuts and avocados.

An interesting and thought provoking topic.

The idea of humans sharing commonalities with the sea lamprey might raise eyebrows, but a groundbreaking study by the Stowers Institute for Medical Research, published in Nature Communications, is flipping conventional wisdom on its head. Discover how this research is rewriting evolutionary narratives at https://amcen.co/3Tg7Oj9. Learn more about the connection between American Century and the Stowers Institute for Medical Research at https://amcen.co/4c3xR4c. #EvolutionaryInsights #ScienceNews #ResearchDiscovery

Calling all aspiring Emergency Medicine researchers! For those of you unable to make his talk at the RCEM ASC, here are some links to insightful and practical advice on getting involved on EM research from Matt Reed, the chair of the RCEM Research and Publication Committee…

We need more discussions like this on how AI can make meaningful contributions to humanity, improved healthcare outcomes being one great example. It’s an area where Canada can and should lead.