National Institutes of Health (NIH): Intramural Research Program (IRP)’s Post

Advancing Liver Disease Research: A Critical Step Forward Liver disease is a significant public health burden, affecting over 850 million people worldwide. It's a leading cause of death, with many cases diagnosed too late. Research is crucial to: - Understand the disease's complexities - Develop effective treatments and therapies - Improve diagnosis and patient outcomes - Reduce the economic burden of liver disease By investing in research, we can: - Enhance patient care and outcomes - Drive innovation in treatment options - Save lives and improve quality of life #LiverDiseaseResearch #HealthcareAdvancement #MedicalInnovation"

Thanks for sharing this great article Kate. A few things jump out: 1) There is still a lot of misunderstanding around liver disease, and it's promising to see conditions like metabolic liver disease attracting more attention in the general media. This article explains the issues perfectly! A huge percentage of people with liver disease do not drink alcohol. 2) There is a danger that when we talk about 1 in 3 people having liver disease, policymakers become paralyzed by the scale of the issue. It's important to note that whilst, according to some reports, 30% of us have some degree of excess fat in our livers, not all will progress to cirrhosis, cancer or liver failure. 3) This is an urgent issue that needs addressing now. Liver-related mortality rates are trending in the wrong direction, unlike most other diseases. More people are developing steatotic (fatty) liver disease, and as comorbidities (like type 2 diabetes) become more common, people are getting sicker, quicker. Add to this the advent of new treatments including Madrigal Pharmaceuticals Resmetirom. We think that one of the keys to getting ahead of this Tsunami* (*credit Roger Green) lies in intelligence gathering and deployment. If you can use real-world data to recognize the patterns in those cases that do progress from simple steatosis to advanced disease, we're no longer talking about treating 1 in 3. We can then use a case-finding approach, and historic blood tests to find these high-risk people BEFORE they progress. “The life depends on the liver”. We couldn't have said it better ourselves. #liverdisease #publichealth #FattyLiver p.s. Thanks to New Scientist for yet another great article.

This #MuscularDystrophyAwarenessMonth, Soleo Health is proud to support Muscular Dystrophy Association’s #30DaysOfStrength to accelerate research, advance care, and empower people living with #neuromuscular diseases. Join us in making an impact today at https://hubs.la/Q02NtK5C0

Systemic consequences of heart failure with preserved ejection fraction include heart, lung, kidney, brain and vascular involvement. #HFpEF #Nature Review Disease Primers (https://lnkd.in/gArFRjB) Each Primer provides a global overview of the field and outlines key open research questions. “The disease Primer serves as a signpost of where the field currently is and where it's heading”. https://lnkd.in/d2h4kArj

The climate crisis is not just an environmental issue, it is a profound health emergency that poses significant risks to global health. The World Health Organisation identifies climate change as one of the greatest threats to human health, contributing to preventable deaths and exacerbating a range of health conditions, including respiratory diseases, heat-related illnesses, and vector-borne diseases.  Our new Havas Lynx white paper #ClimateOfHealth explores this worrying topic in more detail and helps us understand how we, as pharma experts and healthcare professionals, can work together towards a more sustainable future. I urge you to have a read and ask yourself what you can do to contribute towards a brighter future in health and for our planet. To learn more, please view our whitepaper here: https://lnkd.in/eh8EcDCM Or get in touch directly. #ClimateOfHealth #HavasLynx #ImpactThatMatters #HavasHealthNetwork

hello everyone,I like to share about Glutathione. Glutathione is involved in tissue building and repair, making chemicals and proteins needed in the body, and in immune system function. People take glutathione for aging, alcohol use disorder, liver disease, heart disease, and many other conditions, but there is no good scientific evidence to support these uses. #snsdesignthickers #snsdesignthicking #snsinstitutions

It’s finally out! 🎉 Researching for this whitepaper this past year has been my highlight of my time at Havas Lynx so far. I am so proud to have been chosen to be part of it, as sustainability and health has always been a huge interest of mine. It for sure was a challenge as it may have been the biggest research brief I’ve ever received, yet it was so incredibly interesting to find the shocking ways we might have not even thought climate change affects us. Although we as a company are not sustainability experts, the aim of this project is to expose all the impact climate change is having on the disease and therapy areas that exist, and the desperate need for action to be taken. #climateofhealth #climatechangeemergency #sustainability

Transfer and fates of damaged mitochondria: role in health and disease. Mitochondrial transfer is prevalent in vivo and could exhibit diverse functions contingent upon physiological conditions. Therefore, investigating the mechanisms and modalities of cell-dependent mitochondrial transfer across different cell types and their actions in various disease states is critical. https://lnkd.in/eG-66ktk

Havas Lynx's new paper, "Climate of Health," highlights the impact of climate change on every medical therapy area, including respiratory disease, oncology, mental health, cardiovascular disease, women’s health, diabetes, and beyond. Read more in LBBonline - Little Black Book: https://lnkd.in/eWVMfFZv #OneHavas #MeaningfulDifference #HavasLynx

Achieving sustainable weight loss is more than a journey towards an aesthetic ideal; it’s a crucial step towards enhancing overall health and well-being. Research demonstrates that excessive weight can significantly increase the risk of chronic conditions such as diabetes, heart disease, and certain types of cancer