EID journal ’s Post

Global loss of cellular m6A RNA methylation following infection with different SARS-CoV-2 variants. https://lnkd.in/dHr9Tht4

Interested in speaking at Positive Strand RNA Viruses? Submit your abstract to organizers by July 23rd to be considered to give a short talk. Submit your abstract now! https://hubs.la/Q02D1khm0 #KSRNAVirus25 #RNAviruses #positivestrandRNAviruses #vaccinedevelopment #infectiousdiseases #emergingviruses

Breaking free from nucleus confinement to the cytosol, Cas13d-NCS neutralizes self-replicating RNA viruses, presenting a new approach to combat future RNA virus outbreaks: https://lnkd.in/gY98TDes

Breaking free from nucleus confinement to the cytosol, Cas13d-NCS neutralizes self-replicating RNA viruses, presenting a new approach to combat future RNA virus outbreaks: https://lnkd.in/gY98TDes

Our new paper: first evaluation of one vaccine candidate for toxoplasmosis on human cells

A study under Tulane's Dr. Parvatiyar has identified the protein TRIM28 as a potential "universal key" in the activation of the body's innate immune response to different types of #viruses. Deletion of TRIM28 impaired antiviral defense response against both RNA and DNA viruses. #TulaneResearch #Medicine Read the paper in the comments! Image: Schematic demonstrating how detection of different classes of virus converges on a pathway mediated by TRIM28. Activation by TRIM28 of another protein called TBK1 is necessary to signal the cell to begin expressing genes involved in immune response.

Exciting work started in 2021 that achieves so far the most complete view on WWTPs RNA virome: Metatranscriptomic Compendium of 55900 RNA Viruses Deciphers Human Health Implication and Ecological roles of RNA Virome in Global Wastewater Treatment Plants https://lnkd.in/gXc7ZJ28

Most of you got it right! 🎉 It was Paul Ehrlich who hypothesized that side-chain receptors on cells bind to pathogens in a lock-and-key mechanism according to his side-chain theory. He proposed that cells have specific side chains (receptors) on their surfaces that bind to toxins and other antigens, analogous to the chemical side chains in organic compounds. Each cell has multiple side chains, each capable of binding to a specific antigen. Borrowing Emil Fischer's 1894 concept explaining enzyme-substrate interactions, Ehrlich suggested that receptor binding to infectious agents fits like a lock and key. The side-chain theory proposed by Ehrlich in the 19th century is a foundational concept in immunology, marking a significant advancement in understanding how the immune system recognizes and neutralizes foreign substances such as toxins and pathogens. #ScienceAccelerated #Antibodies

The methods for mapping m6A present several challenges for defining m6A function on viral RNA. Here, we propose a framework for improved methods to study the role of m6A on viral RNA. #m6A #virus bit.ly/3xY1vZ4

Fingerstick point-of-care hepatitis C virus RNA assay in a community supervision (probation or parole) setting is feasible, this study finds. https://ja.ma/4gQOEtL