Cannabis Science and Genetics 🧬 Co-Founder and CSO, S3 🧬 Gene Editing 🧬 BetterCannabisThroughScience Consulting 🧬 Molecular Biologist 🧬 Outdoors Enthusiast
"Trust me, bro, the DEA said they don't care about intoxicating hemp derivatives." Oh yeah? Then why are they studying their cannabimimetic effects? That's right, 3 DEA agents listed as co-authors with the research contractor RTI International on this paper, which looked at cannabimimetic effects of minor cannabinoids and synthetic IHDs Δ8-tetrahydrocannabinol (Δ8-THC) and (6aR,9R)-Δ10-tetrahydrocannabinol. I'm not suggesting this is a conspiracy theory. It's well known the DEA is interested in IHDs. But what could this mean for future policy from the DEA? "Delineation of their potential adverse effects, including their ability to produce Δ9-THC-like intoxication, is crucial" "Δ8-THC was the only compound that produced Δ9-THC-like psychoactive effects." And on a side note, despite prior research showing beta-caryophyllene activates CB2 (albeit in the high micromolar range), they claimed "beta-caryophyllene and beta-caryophyllene oxide exhibited negligible affinity for both CB1 and CB2 receptors" #BetterCannabisThroughScience
If I had known the DEA was conducting this type of research, would have applied for a research position years ago.
Johnny Broadcast
6mo
IHD?? (Intoxicating Hemp Derivatives) HDC?? (Hemp Derived Cannabinoids) Any more?? Can we choose ONE and all stick with it?? 🤣😂
Keegan Skeate
6mo
Interesting to see people still abusing poor mice even though we know all studies on lab rats are invalid.
Shannon Moore
6mo
You should be more worried about fentanyl in the US? And the dea
Mice…🐁🐀🐁🤷♂️
David Heldreth
6mo
I find this ironic - Conflict of interest statement Declaration of competing interest The authors declare that they have no known competing financial interests or personal relationships that could have appeared to influence the work reported in this paper.
Dr Geoff Cutter
6mo
#DanielFowler. The date on the paper is “8 June 2024” ?! Getting a little ahead of themselves in more than one way??
Blair Curless
6mo
Good find and thanks for sharing this.
Davið Pittman
5mo
Thanks for sharing… unfortunately their research is flawed and inaccurate on multiple fronts.
Cannabis Science and Genetics 🧬 Co-Founder and CSO, S3 🧬 Gene Editing 🧬 BetterCannabisThroughScience Consulting 🧬 Molecular Biologist 🧬 Outdoors Enthusiast
6moEvaluation of cannabimimetic effects of selected minor cannabinoids and Terpenoids in mice Behind a paywall, DM me https://www.sciencedirect.com/science/article/abs/pii/S0278584624000526?via%3Dihub