AIRA Matrix Private Limited’s Post

📢 Revolutionary Shipping Method Saves Cell Models 📰 DefiniGEN and Atelerix Ltd. have successfully shipped liver cell models from the UK to the US without freezing them to prevent damage and loss of function. 🔬💊 Freezing can cause major challenges in cell-based testing. Atelerix's preservation technology and DefiniGEN's hepatocytes remain stable at ambient temperatures for up to two weeks, making them ideal for drug discovery and toxicology-related research. 🌡️🧪 In vitro liver models provide a controlled environment for testing drugs and reduce the need for live animals. 🐭😊 The collaboration is a game-changer in scientific research and helps reduce the industry's carbon footprint. 🌍🚚 #BioprocessUpdates #cellmodels #freezingdamage #DefiniGEN #Atelerix #livercells #drugdiscovery #toxicologyresearch #invitro #livermodels #scientificresearch #carbonfootprint #shiptoUS #preservationtechnology #hepatocytes #controlledenvironment ▷ Read the full article here: 📎 https://lnkd.in/d-jVVAga

❓ Why are #NAMs so important? Why is Creatio committed to developing and validating NAM?   Highlights of NAM 🌟: 🍀 Address ethical concerns by reducing or replacing the use of animals #3Rs 🔬 Improve scientific validity.  🌍 Meet regulatory standards. 💲 Enhance cost and time efficiency. 👩💼 Facilitate translational research. 💹 Enhance clinical trials success rate. To explore more visit, us at European Society of Toxicology in Vitro ESTIV - #ESTIV2024 booth number 9 📌   #ESTIV24 #toxicology #drugdiscovery #nonanimal #EU #Creatio #UniBarcelona 

Exciting insights into the world of GenEvolutioN's laboratory! 🧪✨ Journey with us through the intricate process of Fluorescent 𝘪𝘯 𝘴𝘪𝘵𝘶 hybridization (Q-FISH) with Telomere and Centromere probes. 💡 Witness the essential steps, from skilled manipulations to utilizing equipment like the Auto Stainer and Cover Slip, that elevates our 𝘪𝘯 𝘷𝘪𝘵𝘳𝘰 toxicology services. Dive into innovation and precision with GenEvolutioN ! #LabInnovation #QFISH #LabTechnology #GenEvolutioNScience

Sandra Czech, PhD student in our Department Mechanistic Toxicology, won a TEER measuring device, that was awarded by the PETA Sciene Consortium International. Congratulations 🤩🚀🥳! She was awarded for the project she is working on as part of her doctoral thesis. The project will focus on the development of new-approach methodologies (#NAM-based methods) for risk assessment of inhalation toxicants. Sandra explains 👩🔬💬: “To mimic the in vivo environment of the lung epithelium, we use primary normal human bronchial epithelial cells (#NHBE) cultured by using air-liquid interface (ALI) technology. Differentiated NHBE cultures will be exposed to typical lung toxicants and transcriptional responses will be analysed. For data analysis, we will move away from single gene comparisons and exploit co-expression and cross-process network analysis of toxicogenomic data. For selected chemicals, we will also measure the transepithelial uptake across NHBE barrier cultures and use these results as input parameter for our inhalation specific #PBPK model.” The new TEER equipment will be used to assess the epithelial barrier function and to implement data on the tightness of NHBE cultures as an indicator for barrier functionality and proper differentiation. This will be particularly important for the planned uptake and transport studies. In addition, TEER will be used as a readout for cell viability. Find out more about the award https://lnkd.in/eCgQnCU9 #toxicology #invitro #PhD #riskassessment #inhalation

🌟 𝐉𝐨𝐢𝐧 𝐔𝐬 𝐉𝐮𝐧𝐞 𝟐𝟓𝐭𝐡 – 𝐓𝐫𝐚𝐧𝐬𝐟𝐨𝐫𝐦 𝐘𝐨𝐮𝐫 𝐑𝐞𝐬𝐞𝐚𝐫𝐜𝐡!🌟 Attention researchers in drug discovery, pre-clinical studies, and toxicology! Don’t miss our exclusive online event. Secure your spot now (link in first comment)! 𝐄𝐯𝐞𝐧𝐭 𝐇𝐢𝐠𝐡𝐥𝐢𝐠𝐡𝐭𝐬: 🧬 𝐋𝐢𝐯𝐞 𝐃𝐞𝐦𝐨 𝐛𝐲 𝐌𝐚𝐭𝐭𝐡𝐢𝐚𝐬 𝐒𝐜𝐡𝐚𝐝𝐞: - Experience our groundbreaking label-free imaging platform in action. - Discover cellular secrets through our advanced AI analysis. 🌟 𝐄𝐱𝐜𝐥𝐮𝐬𝐢𝐯𝐞 𝐖𝐨𝐫𝐥𝐝 𝐏𝐫𝐞𝐦𝐢𝐞𝐫𝐞: - Mathieu Fréchin reveals cutting-edge COVID-19 research with Institut Pasteur (high impact publication coming soon!!) - See the dynamic effects of COVID-19 on cells like never before (video as an example)! 𝐖𝐡𝐲 𝐀𝐭𝐭𝐞𝐧𝐝? - 𝐄𝐚𝐫𝐥𝐲 𝐀𝐜𝐜𝐞𝐬𝐬 to pioneering COVID-19 findings. - 𝐄𝐱𝐩𝐞𝐫𝐭 𝐈𝐧𝐬𝐢𝐠𝐡𝐭𝐬 from leaders in AI biology. - 𝐈𝐧𝐧𝐨𝐯𝐚𝐭𝐢𝐯𝐞 𝐓𝐞𝐜𝐡𝐧𝐨𝐥𝐨𝐠𝐲 at the forefront of live cell imaging. Don't miss this opportunity to advance your research! 🔗 𝐒𝐢𝐠𝐧 𝐮𝐩 𝐧𝐨𝐰! (𝐋𝐢𝐧𝐤 𝐢𝐧 𝐭𝐡𝐞 𝐟𝐢𝐫𝐬𝐭 𝐜𝐨𝐦𝐦𝐞𝐧𝐭) #DrugDiscovery #PreClinicalResearch #Toxicology #COVID19 #LiveCellImaging #NanoliveSA #InstitutPasteur #Innovation #biotechnology

This research article includes a compelling case study illustrating how the NESIL (No Expected Sensitization Induction Level) values predicted by the GARD®skin Dose-Response assay can be practically applied within a QRA framework to establish maximum allowable concentrations of sensitizers across various consumer products. Scientists from SenzaGen, IFF, and the Research Institute for Fragrance Materials, Inc. (RIFM) have collaboratively published a groundbreaking article in Regulatory Toxicology and Pharmacology showing effectiveness of GARD®skin Dose-Response assay. The assay exhibits robust agreement with established human data, showcasing its reliability. View full article here: https://lnkd.in/gjaCU_Gb If you want to integrate this cutting-edge technology for risk assessment of skin sensitizers, email us at [email protected] We are the authorized distributor of SenzaGen's services in India. ............................. #FragranceSafety #QuantitativeRiskAssessment #SkinSensitization #GARDskin #chemicalsafety #invitro #NAMs #genomics #nonanimal #machinelearning #biomedicalresearch #cosmeticsindustry #researchanddevelopment

🚀 The new industry standard in clinical-grade, human-relavant data. 🐟 Our team has engineered a state-of-the-art biosensor system that's revolutionizing the evaluation of cardiovascular function. Why settle for the status quo when you can have: 🔬 Human-relevant, clinical-grade data 💰 Results in a fraction of the time compared to the current standard 📈 A dramatic cost reduction in animal testing and maintenance We're on a mission to make clinical research CHEAPER, FASTER, while delivering BETTER RESULTS. Stay tuned for more updates! #Innovation #HealthTech #biotechnology #hearthealth #CardiovascularResearch #EnvironmentalHealth #environmentaljustice #DefensMedTech #EthicalBioscience #toxicology #Biosensor #DevelopmentalInc #ScienceandTechnology #AlternativeTestingModels

Inotiv’s genetox experts are heading to the Boston area! Are you trying to unravel unexpected results in your genetic toxicology data? Join us for a free seminar on Tuesday, July 9, to learn how to solve your genetox challenges. "Resolving the Unexpected: Strategies for Understanding Genetox Data," presented by Dr. Shambhu Roy and Dr. Cheryl Hobbs, will provide insights into secondary and mechanistic follow-up genetox assays as well as other relevant topics, including nitrosamine impurity testing. https://hubs.ly/Q02BJd4l0 #Inotiv #GeneticToxicology

👀 Did you miss Biobide at the 58th Congress of The European Societies of Toxicology - EUROTOX Congress? Take a look at the carousel! 👩🏼🔬 Ana del Pozo Cano, Senior Study Director in the Neurotoxicity Area, presented a poster about the enormous promise of zebrafish embryos as a New Alternative Methodology (NAM) to distinguish the embryotoxic and thyroid disruptor potential and developmental neurotoxicity of reference chemicals. It's a wrap! Another fulfilling event showcasing the potential of Zebrafish as a high-content strategy for Drug Discovery and Development. See you in the next ones! 👋🏼 #Eurotox2024 #toxicology #teratology #NAMs #Zebrafish #Biobide

Register now for Inotiv’s free genetic toxicology seminar on July 9 to learn how to solve your unexpected genetox results. "Resolving the Unexpected: Strategies for Understanding Genetox Data" will be presented by Dr. Shambhu Roy and Dr. Cheryl Hobbs and will provide insights into secondary and mechanistic follow-up genetox assays as well as other relevant topics, including nitrosamine impurity testing. Join us for this exciting event! https://hubs.ly/Q02F1SvZ0 #Inotiv #GeneticToxicology