Agarose Bead Technologies (ABT)’s Post

🔬 𝐖𝐨𝐫𝐤𝐢𝐧𝐠 𝐰𝐢𝐭𝐡 𝐚𝐩𝐭𝐚𝐦𝐞𝐫𝐬? 𝐓𝐡𝐢𝐬 𝐩𝐨𝐬𝐭 𝐢𝐬 𝐟𝐨𝐫 𝐲𝐨𝐮! 🧬Aptamers are changing the game in biotech! These short DNA or RNA single-stranded molecules with unique structures offer several advantages over traditional antibodies, but here's the scoop: Agarose resins are making aptamer selection even easier! 📈 New research reveals resin choice and metal ions (like Co2+, Cu2+, Ni2+, Zn2+) play a vital role in aptamer selection. The result? Improved binding affinity! 👉 Find out how ABT's IMAC resins have contributed to this result in our latest blog entry: https://lnkd.in/dVP6tAJy! #IMAC #bioprocessing #pharma #chromatography #downstream #scientific #news #ABTechnologies

OPTIMIZING FLOWBOT® ONE FOR DIFFERENT LIQUID CLASSES This application note provides guidance on which parameters to adjust to optimize flowbot ONE for the liquid classes: → Dimethyl sulfoxide (DMSO) → Ethanol → Glycerol → Tween-20   Adjusting critical liquid class parameters and pipetting methods is easily done in flowbot ONE’s Liquid Class Editor, available in its browser-based software.   Check it out here and learn how to easily achieve high accuracy and precision for different solutions: https://lnkd.in/eV-5QGmW #liquidclasses #labautomation #lifescience #biotech #pharma

Check out SeraNovo’s latest study showcasing the power of our LiDES technology!

Amorphous solid dispersions are a great way to tackle bioavailability limitations of poorly soluble drugs. What can be even better than them? For example, SeraNovo's proprietary formulation: a eutectic-based lipidic formulation, creatively named LiDES! Check our latest results where a LiDES formulation with exceptionally high drug loading significantly outperformed a solid dispersion! #SeraNovo #LiDES #poorlysolubledrugs #bioavailabilityenhancement #lipidformulation

SeraNovo's LiDES platform achieves a substantial 2.75x increase in bioavailability compared to ASDs. Dive into the details below for our latest findings. 📊 More exciting news to come, stay tuned! #SeraNovo #SolvingtheInsoluble #PharmaInnovation #Bioavailability #StayTunedForMore #LiDES

When the work matters, you need to do it right - and we do. Our FlowLinX® Sanitary Fittings are compliant to ASME-BPE for single use fluid transfer applications where sanitary processing is critical. Flow through us: https://bit.ly/3iuV1tE #flowlinx #sanitaryfittings #makingwaves #flowthroughus #biotech #pharmaceuticalengineering #pharmaceuticalmanufacturing

SeraNovo's LiDES Achieves 2.75x Higher Bioavailability than Traditional ASDs! 📈 At SeraNovo, our results speak for themselves, and we're thrilled to share our latest success! In our recent case study on the poorly soluble API glibenclamide, our LiDES formulation achieved an impressive 2.75x increase in bioavailability compared to the industry standard, Amorphous Solid Dispersion (ASD). 🚀 But what is LiDES?  In essence, it is the synthesis of eutectic solvents and lipids delivering 10x the drug load with much more bioavailability. 🔬 Case Study Highlights: ✅ Significant Bioavailability Enhancement ✅ Simple Manufacturing ✅ Physical Stability Have questions or want to learn more about our LiDES technology? Feel free to reach out, and let's explore how we can enhance your drug’s bioavailability. 🤝 #SeraNovo #SolvingtheInsoluble #PharmaInnovation #Bioavailability #StayTunedForMore #LiDES

SeraNovo’s second showcase highlights the competitiveness of the LiDES platform. Traditional lipid-based formulations tend to suffer from limited drug loading capabilities, in our experience this includes compounds with Tm > 150C and Log P < 6. Glibenclamide fits these criteria and the solubility in lipid excipients is found to be well below 5 mg/mL. SeraNovo’s LiDES platform yields high bioavailability and enables high drug loading (300mg/mL) in lipid vehicles, even for drugs that do not meet the criteria for classical lipid-based formulations. Many thanks to the team for generating this excellent showcase highlighting the formulation capabilities of the LiDES platform. For those who haven't seen the original post, delve into the details below. #SeraNovo #SolvingtheInsoluble #PharmaInnovation #Bioavailability #StayTunedForMore #LiDES

To all my Biopharma connections who might want to learn more about improving your fluid transfer processes- take a minute to register for this informative talk. #fillfinish #bioprocessing #biopharma #silicone

Learn how our prepacked bioprocess chromatography columns can help you get the most from your ÄKTA ready single-use chromatography system. https://cytiva.link/0mjrw #chromatography #bioprocessing