Today we announced our exclusive license agreement for our Duplex Sequencing Technology with Exact Sciences! For more information, see our press release here: https://lnkd.in/gvKH5Ebt
TwinStrand Biosciences
Biotechnology Research
Seattle, WA 5,348 followers
Ultra-rare variants are detected with unparalleled sensitivity and specificity with TwinStrand Duplex Sequencing
About us
TwinStrand Biosciences Duplex Sequencing patent estate is the foundational technology enabling the ability to accurately identify ultra-low frequency genomic variants that are undetectable by conventional NGS methods. The company's highly sensitive and specific patented Duplex Sequencing technology delivers clearer insights to researchers in applications ranging from residual cancer detection to genetic toxicology. This data can inform critical decisions in public health, and other fields of science on a faster timescale when actions are most impactful. TwinStrand's scientist-leaders have authored more than thirty peer-reviewed articles using Duplex Sequencing technology and have developed a portfolio of more than 150 patents and patent applications. The company has partnered with pharmaceutical companies, academic centers, clinical research networks, molecular diagnostic companies and federal regulatory agencies to bring high precision genomics to the forefront of their science.
- Website
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http://www.twinstrandbio.com/
External link for TwinStrand Biosciences
- Industry
- Biotechnology Research
- Company size
- 51-200 employees
- Headquarters
- Seattle, WA
- Type
- Privately Held
- Specialties
- duplex sequencing, ultra-rare variant detection, genetic toxicity, carcinogenesis, mutagenesis, tumor evolution, error corrected sequencing, direct mutation detection, cloud-based bioinformatics, eliminating NGS noise, sequencing mutation discovery, DNA mixture deconvolution, Microhaplotypes, liquid biopsy, residual disease monitoring, minimum residual disease detection, FFPE, Next-generation sequencing, eliminating NGS background errors, targeted biomarker validation, mutation signature discovery, CRISPR validation, drug candidate selection, targeted DNA sequencing, profiling environmental exposure, and early cancer detection
Locations
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3131 Elliott Ave Suite 750
Seattle, WA 98121, US
Employees at TwinStrand Biosciences
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Martha Weckel
Life Sciences Commercial Executive / Board Member
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Kellie S. Bickel, PhD
SVP, Intellectual Property & Corporate Strategy at TwinStrand Biosciences
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Alice Ly, PhD
Vice President - Alexandria Venture Investments; Head of Alexandria LaunchLabs - Seattle
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Jason Myers
Innovator
Updates
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On #AMLWorldAwarenessDay, we join the #AcuteMyeloidLeukemia community in raising awareness of this aggressive cancer of the blood and bone marrow. Accurate detection of measurable residual disease (MRD) can impact an AML patient’s care. We are proud that our AML MRD assay provides researchers with ultrasensitive detection of mutations in AML, enabling accurate response quantification and remission identification. Spread awareness and learn more about AML from KNOW AML https://lnkd.in/defH4tzy
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Meet with us at #2024SOT in Salt Lake City, March 10th to 14th to learn how you can get in vivo mutation frequency data for nitrosamine impurities from wild-type rodents using Duplex Sequencing. Don’t miss the “Error-Corrected Next-Generation Sequencing Strategies for Direct Assessment of Mutagenesis and Early Identification of Cancer Risk” symposium on Thursday, Mar 14, 8:30 AM - 11:15 AM (MST) in room 251 A You can drop by booth #1334 or schedule a meeting with this link: https://lnkd.in/gDrawMrz @SOToxicology #drugscreening #mutagenesis #genomicsafety
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Going to #2024SOT? TwinStrand Senior Research Technician, Isabel Lee will present her poster on our updated Duplex Sequencing Mutagenesis Assay on Monday Mar 11, 2024 11:45 AM - 1:45:00 PM (MST). Poster Title: An Updated Duplex Sequencing Mutagenesis Assay Accurately and Reproducibly Detects Mutation Frequencies Below One-In-Ten-Million Poster # 197 Drop by booth #1334 or schedule a meeting to learn more! https://lnkd.in/gDrawMrz @SOToxicology #TOXExpo #drugsafety #mutagenesis #toxicology #nitrosamines
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Attending #TANDEM2024? TwinStrand Principal Scientist, Mark McElwain, PhD, will present his poster on the analytical validation of our AML MRD on Thursday, February 22 from 6:45 pm - 7:45 pm. Poster Title: An AML targeted Duplex Sequencing assay can detect Measurable Residual Disease (MRD) at a sensitivity better than 0.01% Variant Allele Frequency Poster #: 122 #TANDEM2024 #AML #MRD #duplexsequencing #ecNGS
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Meet with us at #TANDEM2024 in San Antonio, February 21th to 24th TwinStrand’s team of NGS experts will be there, eager to discuss the advantages of our ultrasensitive AML MRD clinical research testing services, which allow unrivaled sensitivity in detecting variant alleles. Drop by booth #805 or schedule a meeting to learn how we can support your AML research efforts. https://lnkd.in/g3uaAPGn #TANDEM2024 #AML #MRD #duplexsequencing #ecNGS
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Current AML MRD assays lack either the accuracy or the sensitivity to detect all mutations in AML-associated target genes. At #ASH23, December 9-12, visit TwinStrand at booth #3143 or schedule a meeting at the link below to see how Duplex Sequencing virtually eliminates amplification and sequencing errors, allowing ultrasensitive AML MRD detection. https://hubs.li/Q02bzzZc0 #acutemyeloidleukemia #AML #MRD #Cancer #hematology
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Hello network! This one is in my hometown so I'll be in attendance :) If you're going I'd love to connect. DM me or swing by the booth.
Who’s ready for #ASH23 in San Diego, December 9-12? TwinStrand’s team is eager to discuss the advantages of our RUO – soon to be clinical - ultrasensitive AML MRD testing services, which allow unrivaled sensitivity in detecting variant alleles across AML-associated genes. Drop by booth 3143 or schedule a meeting to learn how we can support your AML clinical trial program. https://hubs.li/Q02bPKDV0 #AML #MRD #hematologyoncology #acutemyeloidleukemia
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Who’s ready for #ASH23 in San Diego, December 9-12? TwinStrand’s team is eager to discuss the advantages of our RUO – soon to be clinical - ultrasensitive AML MRD testing services, which allow unrivaled sensitivity in detecting variant alleles across AML-associated genes. Drop by booth 3143 or schedule a meeting to learn how we can support your AML clinical trial program. https://hubs.li/Q02bPKDV0 #AML #MRD #hematologyoncology #acutemyeloidleukemia
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