We're thrilled to share our recent publication in Nature Portfolio showcasing the unique structure of anelloviruses. By leveraging their structurally-derived immune evasion properties, our team is developing potentially safer vectors through our novel Anellogy™ platform to transform the future of #GeneticMedicines. To learn more about anelloviruses and the promise they hold in the #GeneticMedicine space, read here: https://lnkd.in/gCdPNqeD
Ring Therapeutics
Biotechnology Research
Cambridge, Massachusetts 13,459 followers
Founded by Flagship Pioneering, Ring is powering a new era of gene therapy
About us
Powering a new era of gene therapy. An Important Note About Privacy: Ring Therapeutics is committed to your privacy and will not ask for sensitive personal information such as social security number, date of birth or bank account details via email or social media platforms. We do not interview candidates on Telegram, Wire, Google Hangouts or similar public platforms. Any questions about job listings can be directed to [email protected].
- Website
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http://www.ringtx.com
External link for Ring Therapeutics
- Industry
- Biotechnology Research
- Company size
- 11-50 employees
- Headquarters
- Cambridge, Massachusetts
- Type
- Privately Held
- Founded
- 2017
Locations
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Primary
Cambridge, Massachusetts 02139, US
Employees at Ring Therapeutics
Updates
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Check out the latest episode of CGTLive where our Chief Medical Officer and Head of Translational Research, Chris Wright, MD, PhD, highlighted our latest data findings unveiled at ASGCT 2024. To learn more about the promise of anelloviruses and how we’re harnessing their natural capabilities through our novel Anellogy TM Platform, watch the full interview here: https://bit.ly/3A48ZLs
Chris Wright, MD, PhD, on Anelloviruses, a Potential Alternative to AAV for Gene Therapy
cgtlive.com
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🧬🔬 Happy #NationalInternDay! Our co-ops Kesav Ram Singh, Maddie Schanen, Dhatri Mishra, Tyler Gauthier, Tanisha Garg, Sudhan Dhavle, Robert Fletcher, Willow Klein, Utsav Mesvani, Tanmay Nimbulkar, and Sally Howard are helping us push the boundaries of what is possible and we’re so thankful for their hard work and dedication to the team. The future of #biotech is bright, and we can’t wait to see where these #FutureLeaders end up.
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🏓 Last month, our team swapped lab coats for paddles and had a blast on the #Pickleball court for our summer outing. It was an evening full of games, laughs, and celebrations in honor of our 7th anniversary! Check out these photos from the event!
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Earlier this month, we closed our offices for a #SummerShutdown to allow our team to rest, rejuvenate, and participate in summer activities that matter to them! At Ring, we prioritize a healthy work-life-balance to ensure our team remains resilient, motivated, and well-rested so we can continue to revolutionize programmable medicines.
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Exciting news from Flagship Pioneering as they announce the raise of $3.6 billion to fuel breakthrough innovations that transform human health and sustainability. We are proud to be #FlagshipFounded and part of an ecosystem of companies – present and future – taking bold scientific leaps to deliver a better future for all.
Flagship Pioneering raises $3.6 billion to fuel critical breakthroughs in human health and sustainability. This expanded capital pool will accelerate the impact of original science and the creation and development of an estimated 25 breakthrough companies in human health, sustainability, and artificial intelligence. Hear from Flagship Founder and CEO Noubar Afeyan about how we're taking #BiggerLeaps by leveraging the power of generative AI, forging novel partnerships with pharma to speed drug development, expanding globally, and promoting and hiring top talent to our leadership ranks. Read the full press release: https://bit.ly/4eQfx05
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Did you know most people already have antibodies to AAVs, limiting accessibility of current gene therapy treatments? Unlike AAVs, anelloviruses do not elicit a robust immune response, enabling Anellovectors to deliver #GeneticMedicine to almost anyone, including those with pre-existing anti-AAV immunity. Learn more: https://bit.ly/3XwjmkQ
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📆 Mark your calendars for the upcoming panel at Biotechnology Innovation Organization’s #BIO2024! Our CEO, Tuyen Ong, MD, MBA, will be speaking on a panel discussing partnerships and potential in Singapore’s #biotech ecosystem. Request to join below:
Heading to 🧬BIO2024 in San Diego next week? 🇺🇸 📢 Don't miss the event co-organized by the National Health Innovation Centre (NHIC) and Enterprise Singapore! Join us to explore exciting partnering and investment opportunities within Singapore's vibrant biotech innovation ecosystem. Meet our Director, Dr. Pauline Erica Tay, and I&E Manager, Dr. Yon Jin Chuah, Roger, along with rest of the 🇸🇬Singapore delegation. We look forward to engaging with you! RSVP 🔗 https://lu.ma/c0przf79 A*STAR - Agency for Science, Technology and Research EDBI Pte Ltd ClavystBio JLABS Ring Therapeutics KYAN Technologies #BIO2024 #Biotech #Innovation #Partnering #Investment #Singapore
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In case you missed it, we presented new preclinical data on our Anellovectors at #ASGCT2024! It was an exciting opportunity for our team, including our CEO Tuyen Ong, to be on the ground with other #biotech experts and share our unique approach to transforming the future of #GeneticMedicine. Visit our website to dive deeper into our presentations: https://lnkd.in/eiGvaE6f
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Such an exciting milestone to present at #ASGCT2024 alongside these other #FlagshipFounded companies! Check out the full summary and highlights to learn more about the redosability and expanded payload capacity of our novel Anellovectors, a new class of viral vector.
Flagship-founded companies joined other leaders in #cellandgenetherapy at the American Society of Gene & Cell Therapy's Annual Meeting, sharing strides in the development of their respective bioplatform technologies and progress toward potentially transformative medicines. Read the full summary and highlights below: https://lnkd.in/emmmbgbN 🔷 Ring Therapeutics shared data in nonhuman primates showing the ability to redose genetic medicines using their vectors based on a little-known class of viruses called anelloviruses. 🔷 Tessera Therapeutics displayed curative results in humanized mouse models using its Gene Writers and proprietary lipid nanoparticles to restore normal hemoglobin production in hematopoietic stem cells in the bone marrow without chemotherapy or mobilization for the treatment of #sicklecelldisease. 🔷 Alltrna demonstrated robust ability to readthrough premature stop codons in mouse models, promising preclinical results that suggest their engineered tRNAs could offer a versatile approach to rescue protein production in rare and ulta-rare diseases caused by nonsense mutations, known as stop codon disease. 🔷 Omega Therapeutics showed preclinical data highlighting their ability to program epigenetic controllers to upregulate gene expression for a variety of genes types and cell conditions, providing effects that last weeks to months after a single dose. 🔷 Sana Biotechnology, Inc. displayed data showing a promising safety profile for their in vivo CAR T therapy, suggesting its potential to offer comparable efficacy and genomic safety as established treatments.
Flagship at ASGCT 2024
flagshippioneering.com