Ophthopedia

Ophthopedia Update:Longitudinal changes in retina and choroid across novel subtypes of diabetes mellitus: This study aimed to investigate longitudinal changes in choroidal thickness (CT) and ganglion cell-inner plexiform layer thickness (GC-IPLT) across distinct phenotypes of type 2 diabetes mellitus (T2DM) patients. #Ophthalmology #Ophthotwitter #Scicomm

Ophthopedia Update:Association between Glucagon-Like Peptide 1 (GLP-1) Receptor Agonists Exposure and Intraocular Pressure Change: The pathophysiology of glaucoma is complex, multifaceted, and not fully understood. 1–3 It has been hypothesized that elevated intraocular pressure (IOP) and impaired retinal blood flow are initiating factors in glaucomatous optic nerve damage. 3 The onset of retinal neurodegeneration in glaucoma may also be influenced by cumulative oxidative stress in conjunction with chronic mechanical and vascular stress. 4 Oxidative stress is closely linked to cellular senescence, mitochondrial dysfunction, excitotoxicity, and neuroinflammation, all contributing factors to glaucoma progression. #Ophthalmology #Ophthotwitter #Scicomm

Ophthopedia Update:Multifocal Vitelliform Paravascular Retinopathy (MVPR): A New Disorder in the Vitelliform Spectrum: To describe a new retinal phenotype characterized by bilateral, multifocal, subretinal vitelliform lesions along the vascular arcades that we refer to as multifocal vitelliform paravascular retinopathy (MVPR). #Ophthalmology #Ophthotwitter #Scicomm

Ophthopedia Update:Changes in anterior segment after short-term scleral lens wear in healthy Chinese population: To evaluate the impact of short-term scleral lens (SL) wear on anterior chamber (AC) dimension and central corneal thickness (CCT) in healthy Chinese people. #eye #Ophthalmology #CLAE

Ophthopedia Update:Prospective registry-based external validation cohort analysis of dry eye disease subtype classification criteria: Dry eye disease is recognised to be a highly heterogeneous and multifactorial condition with a myriad of etiological drivers [1–3], and subtype classification evaluation is therefore critical for guiding tailored management strategies for individual patients in clinical practice [4–7]. Moreover, subtype classification markers of dry eye disease are also essential for the purposes of informing disease definition in epidemiology studies, and outcome measures in clinical trials [4,8–12]. However, to date, there is a lack of standardised approach in dry eye disease subtype classification criteria in the scientific literature [4]. #eye #Ophthalmology #CLAE

Ophthopedia Update:Costs and cost-effectiveness of the Kerala pilot screening programme for diabetic retinopathy in the public health system: Eye, Published online: 03 September 2024; doi:10.1038/s41433-024-03304-wCosts and cost-effectiveness of the Kerala pilot screening programme for diabetic retinopathy in the public health system #Ophthalmology #Eye #Ophthotwitter

Ophthopedia Update:Treatment for Noninfectious Uveitic Macular Edema with Periocular and Intraocular Corticosteroid Therapies: Periocular, suprachoroidal, and intravitreal corticosteroid therapies are effective treatments for non-infectious uveitic macular edema. Raised intraocular pressure and progression of cataract are among the potential complications. #Ophthalmology #Eyecare

Ophthopedia Update:Short-term choroidal changes as early indicators for future myopic shift in primary school children: results of a 2-year cohort study: Background To assess predictive value of short-term choroidal changes for future myopic shift in children.Methods 577 eyes of 289 primary school children were prospectively followed for 2 years. Cycloplegic refractions at baseline, 1 year and 2 years, and choroidal measurements by optical coherence tomography at baseline and 3 months, were used for analyses. Myopic shift was defined as refraction change of at least –0.50 dioptre/year, at 2 years compared with baseline.Results 228 participants (455 eyes) completed 2-year follow-up. Approximately 37.6% of 311 initially non-myopic eyes and 73.6% of 144 initially myopic eyes developed a myopic shift. Notably, at 3 months greater reductions were found in initially myopic eyes with myopic shift, than in those without myopic shift—in choroidal thickness (ChT), luminal area (LA), stromal area (SA) and total choroidal area (TCA), but no significant differences in any choroidal parameters were observed between non-myopic eyes, with and without myopic shift. Multivariable analyses showed that in myopic eyes, each percentage increase in ChT, LA, SA and TCA was associated with reduced odds of myopic shift (all p #Ophthalmology #Ophthotwitter #BJO

Ophthopedia Update:Amblyopic Eye Vision Recovery Is Seen in Adults With Fellow Eye Vision Loss: A systematic literature review and narrative synthesis were conducted to identify the prevalence and magnitude of amblyopic eye visual acuity recovery after fellow eye injury or vision loss in adult patients. #Ophthalmology #News

Ophthopedia Update:Safety protocols, precautions, and countermeasures aboard the International Space Station (ISS) to prevent ocular injury: The International Space Station (ISS) is a $100 billion epicenter of human activity in the vacuum of space, displaying mankind’s collective endeavor to explore the cosmic frontier. Even within the marvels of technological sophistication aboard the ISS, the human eye remains a highly vulnerable structure. In the absence of multiple layers of protection and risk assessments, crewmembers would face a substantial increase in vulnerability to ocular injury. Aside from stringent preflight screening criteria for astronauts, the ISS is equipped with ophthalmic medications, environmental control and life support systems (e.g., humidity regulation, carbon dioxide removal, pressurized device regulators), and radiation protection to reduce ocular injury. #Ophthalmology #Eye #Ophthotwitter