Empress Therapeutics

Combining the versatility of small molecules with the programmability of biologic therapies, Empress is creating a recipe for novel drug discovery and development inspired by the chemistry already in our bodies. In this Scrip Emerging Company profile, Empress CEO and cofounder Jason Park talks to Joseph Haas about how the company's Chemilogics platform uses AI, synthetic biology and genetic engineering to find novel chemistry and drug targets to provide new therapies across a wide range of indications. Read it on Citeline: https://lnkd.in/dDFtc2Uw #inflammation #immunology #oncology #metabolicdisease #AI #geneticengineering #synbio #drugdevelopment #drugdiscovery #Chemilogics #chemistry #machinelearning #FlagshipFounded

There's nothing better than evolution to inform scientists about what works, through experiments of nature conducted over eons. We share Steven Gygi's excitement about the potential for harnessing insights from the medicinal chemists inside our bodies, and we were delighted to welcome the cell biologist and proteomics pioneer as a guest speaker for the #EMPIREexternal seminar series. The Harvard Medical School professor of Gygi Lab and Director of the Thermo Fisher Scientific Center for Multiplexed Proteomics spoke about his work creating a genome-scale map of the protein-protein interaction landscape in cells. We caught up with him afterwards for further insights into new technologies to better understand small molecule mechanisms of action. 🎥 See what he had to say in this short video. #smallmolecule #drugdiscovery #AI #machinelearning #chemistry #computationalbiology #Chemilogics #microbiome #microbiology #BioPlex #proteomics

With a record number of more than 120,000 visitors and 2,000 participants, BIO Asia–Taiwan was one of the highlights of our 2024 conference calendar! Sabrina Yang, Empress Co-founder & Chief Innovation Officer and Senior Principal Flagship Pioneering took the stage alongside colleague @André Andonian to talk about how novel business models and international collaborations can help emerging #biotech companies build the future of medical innovation. Thank you to the organizers and attendees who participated in the engaging session! #Chemilogics #smallmolecule #drugdiscovery #AI #machinelearning #business #medtech #FlagshipFounded

We had a Taste of Summer ice cream party with #TeamEmpress and our neighbors at Sonata Therapeutics. People got creative with ice cream combos like affogato and ice cream floats. Thanks to the team for bringing together so many flavors and toppings. It was the perfect way to cool down on a hot summer day!

#TeamEmpress volunteered at The Greater Boston Food Bank, an amazing organization that provides healthy food and resources needed to thrive and end hunger across Eastern Massachusetts. #GivingBack #CompanyCulture #EndHungerHere

How can novel business models and international collaborations help emerging #biotech companies navigate the future of medical innovation? Empress co-founder and Chief Innovation Officer Sabrina Yang will be sharing her insights at #BIOAsiaTaiwan. See the agenda here: https://lnkd.in/gdi4Ph5g #Chemilogics #smallmolecule #drugdiscovery #AI #machinelearning #business #medtech #FlagshipFounded

New podcast episode just dropped 🎧! Empress Cofounder and Chief Innovation Officer Sabrina Yang discusses how the human body is an untapped hunting ground for new medicines. The biosynthetic genes in our metagenome are equivalent in size to roughly 50% of the human genome. That's about a meter of non-human genetic DNA inside of us waiting to be decoded and turned into potential medicines. She explains how the #Chemilogics platform can “read” the DNA code and use #AI to predict genes that are most likely to encode small molecules that play a causal role in health and disease. Empress then recodes these genes using synthetic biology, engineering microbes to produce compounds to create new small molecules with the potential to treat many diseases and disorders. 🎙️Listen to her full interview on the #BioReport #podcast with Daniel Levine: https://lnkd.in/dSkDUgBr #Chemilogics #smallmolecule #drugdiscovery #AI #machinelearning #microbiome #drugdiscovery

Companies pioneering original science are essential to making better drugs, faster. We're proud to be part of the #FlagshipFounded ecosystem of companies – present and future – taking bold scientific leaps to deliver a better future for all. Learn more about our #Chemilogics platform that applies the power of #geneticchemistry to discover new medicines at unprecedented speed and scale: https://www.empresstx.com/

We are excited to share that Nature Biotechnology highlighted Empress Therapeutics as a top startup! We were recognized for the breakthrough principle of using co-evolution to guide the discovery of drugs by finding biologically active small molecules encoded in human metagenomic data. Empress scientists estimate that 10^24 possible chemical compounds have been made and tested inside the bodies of humans by co-evolved microbial chemists – greater than any in silico or physical library, and with the added advantages of built-in human relevance and compatibility. We analyze genes encoding biosynthetic pathways that make these compounds to draw associations with health or disease, then use AI and synthetic biology to generate drug leads from gene data. The impact? Predictability and speed in small molecule drug discovery. Read the article to learn more: https://lnkd.in/gsZ-kPqc #FlagshipFounded #Chemilogics #smallmolecule #drugdiscovery #AI #synbio

🏳️🌈 What a great way to celebrate the diversity of our #TeamEmpress family. And to do so with our friends at Sonata Therapeutics was an added treat! Thanks for a great #Pride2024 Out & Proud happy hour. #DEI #diversityandinclusion #LGBTQSTEM #STEMPride #LGBTQIA2S+