- Dustin Hoffman
- Raymond 'Ray' Babbitt
- Tom Cruise
- Charles Sanford 'Charlie' Babbitt
- Valeria Golino
- Susanna
- Gerald R. Molen
- Dr. Bruner
- Jack Murdock
- John Mooney, Will Executor
- Michael D. Roberts
- Vern
- Ralph Seymour
- Lenny
- Lucinda Jenney
- Iris
- Bonnie Hunt
- Sally Dibbs, Diner Waitress
- Barry Levinson
- Director
- Ronald Bass
- Screenwriter
- Barry Morrow
- Screenwriter
- Mark Johnson
- Producer
- Peter Guber
- Executive Producer
- Jon Peters
- Executive Producer
- John Seale
- Cinematographer
- Stu Linder
- Film Editing
- Hans Zimmer
- Original Music
- Ida Random
- Production Design
- William A. Elliott
- Art Director
- Linda DeScenna
- Set Decoration
- Bernie Pollack
- Costume Design
- Louis DiGiaimo
- Casting
- David McGiffert
- First Assistant Director
