Computer Science > Computer Vision and Pattern Recognition
[Submitted on 17 Jan 2019 (v1), last revised 26 Nov 2019 (this version, v3)]
Title:Visual enhancement of Cone-beam CT by use of CycleGAN
View PDFAbstract:Cone-beam computed tomography (CBCT) offers advantages over conventional fan-beam CT in that it requires a shorter time and less exposure to obtain images. CBCT has found a wide variety of applications in patient positioning for image-guided radiation therapy, extracting radiomic information for designing patient-specific treatment, and computing fractional dose distributions for adaptive radiation therapy. However, CBCT images suffer from low soft-tissue contrast, noise, and artifacts compared to conventional fan-beam CT images. Therefore, it is essential to improve the image quality of CBCT. In this paper, we propose a synthetic approach to translate CBCT images with deep neural networks. Our method requires only unpaired and unaligned CBCT images and planning fan-beam CT (PlanCT) images for training. Once trained, 3D reconstructed CBCT images can be directly translated to high-quality PlanCT-like images. We demonstrate the effectiveness of our method with images obtained from 24 prostate patients, and we provide a statistical and visual comparison. The image quality of the translated images shows substantial improvement in voxel values, spatial uniformity, and artifact suppression compared to those of the original CBCT. The anatomical structures of the original CBCT images were also well preserved in the translated images. Our method enables more accurate adaptive radiation therapy, and opens up new applications for CBCT that hinge on high-quality images.
Submission history
From: Shizuo Kaji [view email][v1] Thu, 17 Jan 2019 13:02:59 UTC (1,789 KB)
[v2] Sat, 28 Sep 2019 03:43:02 UTC (1,342 KB)
[v3] Tue, 26 Nov 2019 04:46:55 UTC (1,184 KB)
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