Human Anatomy

The actual underlying mechanism of alterations in testicular histomorphometric parameters resulting from diabetes-induced oxidative stress is still not well understood because of the absence of supporting evidence from scientific experiments. This study was conducted to investigate the correlation between serum oxidative stress markers with testicular histomorphometric parameters and reticular fiber density of Streptozotocin-induced diabetic Wistar rat. The experiment included twenty eight adult male rats sorted into four groups, Group A (Control), other animals were sorted into treatment groups based on their blood glucose levels after inducing diabetes with 65 mg/kg/bw of streptozotocin, Groups B (100 - 200 mmol/l), Group C (210 - 250 mmol/l), Group D (260 - 300 mmol/l). At termination, Serum superoxide dimutase (SOD), catalase and melondialdehyde where evaluated using reagent based antioxidant enzyme assay while reticulum stain kits was used to demonstrate for reticular fiber den...

Gastric outlet obstruction (GOO) is caused by benign or malignant conditions. Benign causes are commoner in patients below 40 years of age while malignant causes are commoner above this age. Cicatrization and edema from chronic duodenal ulceration is the commonest benign cause in our environment (50-65%), while carcinoma of the head of pancreas is the commonest malignant cause. GOO from postoperative adhesions is uncommon. We present a 62-year-old female who was seen with features of GOO from postoperative adhesions following an open cholecystectomy in our facility. A barium meal and follow-through confirmed the clinical impression of GOO. She had adhesiolysis and a prophylactic gastrojejunostomy at laparotomy with satisfactory results. Laparoscopic cholecystectomy is the way to go as this may not have been attended by this complication. Conclusion: This case has highlighted the rarity of GOO from adhesions following open cholecystectomy and the usefulness of barium meal and follow-...