Ochre Bio

🚀 Announcing our new multi-year data licence agreement with GSK to investigate the drivers of liver disease! This partnership will provide GSK with access to our advanced computational biology, cellular and perfused human organ platforms to generate proprietary human liver datasets. The data will be used by both GSK and Ochre Bio to build better AI models – allowing for fewer, but more precise, experiments to aid in target choice. The deal has a total value of up to $37.5m for both co-exclusive and non-exclusive data licences. "Data innovation is as important as algorithmic innovation when investing in ML workflows. Both Ochre Bio and GSK share a commitment to providing liver disease patients with more effective medicines and believe in the power of computational modelling to improve therapeutic discovery. These large-scale, causal human datasets will be foundational for our respective liver pipelines." - Jack O'Meara, Co-Founder and CEO. Read our full announcement ➡️ https://lnkd.in/eeETgHV6 #TeamOchre #biotech #genomics #LiverDisease BACKED VC Khosla Ventures Norrsken VC BoxOne Ventures Hoxton Ventures Apollo Ventures Y Combinator LifeLink Ventures Taavet+Sten SSI Strategy Entrepreneur First Pledge Ventures Alexandria Real Estate Equities, Inc.

We have three new additions to our Ochre Bio team! Say hello to Ran Li, Ludo Wesolowski, our two new Senior scientists, and Chia-An Li, our new Research Associate 👋 💻 Ran Li is a computational biologist with a PhD in population genetics, a postdoc from the University of Oxford, and over a decade of experience analysing NGS data. 🧬 Ludo Wesolowski is a Bioinformatician with a PhD in developmental programs in renal cancer from the University of Cambridge and extensive experience in transcriptomics. 🧫 Chia-An Li has a background in oncology research from undertaking a master’s degree, which provided experience in cell culture and molecular biology. Welcome to Ochre Bio, Ran, Ludo, and Chia-An! #TeamOchre #Biotech #Genomics #LiverDisease

🏆 We’re excited to announce that Ochre Bio has been named a finalist for Biotech Company of the Year at the Pharma Industry Awards 2024! This nomination celebrates the progress we’ve made this year in tackling late-stage liver disease through precision RNA medicine and deep phenotyping, and also our partnerships with Boehringer Ingelheim and GSK. We’re honoured to be recognised for our hard work this year. We're honoured to be amongst strong finalists and excited for the awards night on the 18th of September! Check out the full shortlist: https://lnkd.in/dRwB3id4 #TeamOchre #Biotech #Genomics #LiverDisease #PharmaIndustryAwards

🙌 September is shaping up to be an eventful month, with two exciting events for our team on the horizon. Here’s what we’re up to: Jack Castle, our Head of Corporate Development & Business Operations, will be discussing pharma partnership strategies for biotech companies with Ruey-Bing Yang from the Innovation Incubator Center, Taiwan and Tess Tsai-Hsiu Lu, our Head of Early Validation. 📅 12th September, 9:30 - 11:00 AM 📍BioTReC, Taipei City Register to join: https://lnkd.in/ePGTQR3C Next week, catch Quin Wills, our Co-Founder and CSO, at the ECCB Conference, staying on top of the latest trends in bioinformatics and computational biology: 📅 16th-20th September 📍 Turku, Finland Full Programme: https://lnkd.in/dwFFRsnu Get in touch with Quin if you’re attending and want to arrange a meeting! #TeamOchre #Biotech #Genomics #LiverDisease

🎉 This summer, our talented team members have been putting in some incredible effort, and we’re excited to announce the following well-deserved promotions: 🔸 Fleur Palmer-Paquis, Scientist I 🔸 Esther Arnaiz González, Scientist II 🔸 Sachin Patil, Senior Scientist I 🔸 Nicholas Taylor, Senior Scientist I 🔸 Robert Mart, Director (Head of Lead Development) A huge congratulations to all, and thank you for your continued dedication! 👏 #TeamOchre #Biotech #Genomics #LiverDisease

"A better understanding of the pathological processes that drive MASH is critical to creating effective treatments." MASH (Metabolic Dysfunction-associated Steatohepatitis) plays a significant role in the progression of late-stage liver diseases like cirrhosis and liver cancer. Recent research from Sanford Burnham Prebys and UC San Diego has identified specific macrophages that could support liver repair in patients with advanced fibrosis, where scar tissue hampers the liver's ability to function. Understanding the signatures of complex liver disease processes is vital if we are to drive forward the development of more effective therapies for late-stage liver diseases. With such a high number of people affected by liver disease – and often not being diagnosed until the disease has progressed to its later stages – the number of people who could benefit from these new therapies is huge, which is why better understanding the processes of late-stage liver disease is a key focus for us at Ochre Bio. Learn more about the research ➡️ https://lnkd.in/eaSxarDs Covered by ➡️ https://lnkd.in/eA-MeA_R #TeamOchre #Biotech #Genomics #LiverDisease

🌟 We’re honoured that Ochre Bio has been selected by both Sifted and EU Startup News' as a top biotech startup of 2024 Inclusion on these prestigious shortlists is the cherry on top of a year of big wins for the team and reflects the huge amount of hard work that's been put in by all. We hugely value the recognition of our mission to advance the treatment of late-stage liver disease through precision RNA medicine and deep phenotyping, which has been advanced this year following partnerships with Boehringer Ingelheim Ingelheim and GSK Read more: 1️⃣ https://lnkd.in/eFZbvAeg 2️⃣ https://lnkd.in/dVeUhW8p #TeamOchre #Biotech #Genomics #LiverDisease

🎉 Celebrating Wheaton's Day at our Oxford site! Every year we celebrate Wheaton's Day, as a reminder of one of our core principles: "Don't be a d*ck! When others fail you, support them." This year, the team took part in a back-2-back origami workshop, where pairs worked together to create origami models: one person explained, and the other folded. This exercise emphasises the importance of effective communication towards a common goal, and reminded the team to think about others before speaking. The afternoon – fuelled by Wheaton's Day cupcakes – equipped the team with some fun, practical skills to boost our daily interactions ⬇️ #TeamOchre #biotech #genomics #LiverDisease

Welcoming two new members to our NY team! Say hello to Nicola de Prisco, PhD, our new Scientist, and Ahmad Bashir Barekzai, our new Clinical Research Scientist 👋 🧬 Nicola has a Ph.D. in Human Genetics from TIGEM in Italy and brings extensive expertise in molecular therapy and liver biology, honed at top institutions such as Temple and Columbia University. 📸 Outside the lab, Nicola loves capturing moments through street photography, enjoying theatre, travelling the world, and trying different cuisines with his wife. 🩺 Ahmad is a fully trained general surgeon and surgical oncologist with experience in practising surgery in Afghanistan, India and Türkiye. He completed his clinical research fellowship in the Hepatopancreatobiliary Service of Memorial Sloan Kettering Cancer Center. 📚Outside of work, Ahmad likes to spend his free time reading books and spending quality time with family. Welcome to Ochre Bio, Nicola and Ahmad! #TeamOchre #biotech #genomics #LiverDisease

We recently had a visit from BBC Click...👀 Lara Lewington swung by our Oxford labs to talk to Quin Wills, CSO and Co-Founder; Kenny Moore, Head of Research; and Robert Mart, Head of Lead Development, about our work developing RNA therapies for chronic liver disease, and our human-first approach to tackling it. “We’re sequencing livers across the world and in incredible detail, right down to the level of individual cells and we use all that data to find out which genes we need to think about for therapy development.” – Quin Wills Thanks so much Lara for making this experience so enjoyable – you're welcome back anytime! Have a peek inside our labs now, in the final BBC Click episode of the season: https://lnkd.in/erU4xxUT #TeamOchre #biotech #genomics #LiverDisease