Journal of psychosomatic obstetrics and gynaecology, Jan 9, 2015
Objective: To explore the effect of ever having tried to conceive for more than 12 months on leve... more Objective: To explore the effect of ever having tried to conceive for more than 12 months on levels of anxiety and depressive symptoms and to investigate if symptom levels of anxiety and depression in infertile women who remain childless, or go on to have children, respectively, differ from symptom levels in mothers without reports of infertility. Methods: Analyses were based on information from 12 584 Norwegian women aged 19-45 years who participated in the North-Trøndelag Health Study from 1995 to 1997 and data from the Medical Birth Registry of Norway. Anxiety and depressive symptoms were measured by the Hospital Anxiety and Depression Scale. Results: Having tried to conceive for more than 12 months (ever) was weakly associated with higher levels of depressive symptoms. In the categorical analyses, women with resolved infertility had higher levels of anxiety symptoms (B = 0.25 (95% confidence interval (CI) = 0.04-0.47)) and voluntarily childfree had lower levels of depressive sym...
To compare the effects of right unilateral (RUL) electroconvulsive therapy (ECT) and algorithm-ba... more To compare the effects of right unilateral (RUL) electroconvulsive therapy (ECT) and algorithm-based pharmacologic treatment (APT) on neurocognitive function in treatment-resistant bipolar disorder depression. Inpatients with DSM-IV-TR-diagnosed, treatment-resistant bipolar depression, who were acutely admitted to 1 of the 7 clinical study centers in Norway, were recruited from May 2008 to April 2011 into a prospective, randomized controlled, 6-week acute treatment trial. General neurocognitive function was assessed with the MATRICS Consensus Cognitive Battery (MCCB), and retrograde memory for autobiographical events was assessed with the Autobiographical Memory Interview-Short Form (AMI-SF) before and shortly after (mean = 23.5 days) a trial with either RUL brief-pulse ECT (mean dose = 233.3 mC) or APT. Seventy-three patients entered, and 39 (nECT = 19, nAPT = 20) completed. Both groups showed improvements in all MCCB domain scores, with no significant differences between the study...
Objective. To explore the effect of ever having tried to conceive for more than 12 months on leve... more Objective. To explore the effect of ever having tried to conceive for more than 12 months on levels of anxiety and depressive symptoms, and to investigate if symptom levels of anxiety and depression in infertile women who remain childless, or go on to have children, respectively, differ from symptom levels in mothers without reports of infertility. Methods. Analyses were based information from 12,584 Norwegian women aged 19-45 who participated in the North-Trøndelag Health Study 1995-97 and data from the Medical Birth Registry of Norway. Anxiety and depressive symptoms were measured by the Hospital Anxiety and Depression Scale. Results. Having tried to conceive for more than 12 months (ever) was weakly associated with higher levels of depressive symptoms. In the categorical analyses, women with resolved infertility had higher levels of anxiety symptoms (B=0.25 (95% CI=0.04; 0.47)), and voluntarily childfree had lower levels of depressive symptoms (B=-0.05 (95% CI=-0.50; -0.21)), than mothers without infertility. However, women with current primary or current secondary infertility had levels of anxiety and depression not significantly different from mothers without infertility. Conclusion. At the population level, and taking a longitudinal perspective, unresolved infertility is less burdensome than findings from studies on women seeking help for infertility suggest.
Journal of psychosomatic obstetrics and gynaecology, Jan 9, 2015
Objective: To explore the effect of ever having tried to conceive for more than 12 months on leve... more Objective: To explore the effect of ever having tried to conceive for more than 12 months on levels of anxiety and depressive symptoms and to investigate if symptom levels of anxiety and depression in infertile women who remain childless, or go on to have children, respectively, differ from symptom levels in mothers without reports of infertility. Methods: Analyses were based on information from 12 584 Norwegian women aged 19-45 years who participated in the North-Trøndelag Health Study from 1995 to 1997 and data from the Medical Birth Registry of Norway. Anxiety and depressive symptoms were measured by the Hospital Anxiety and Depression Scale. Results: Having tried to conceive for more than 12 months (ever) was weakly associated with higher levels of depressive symptoms. In the categorical analyses, women with resolved infertility had higher levels of anxiety symptoms (B = 0.25 (95% confidence interval (CI) = 0.04-0.47)) and voluntarily childfree had lower levels of depressive sym...
To compare the effects of right unilateral (RUL) electroconvulsive therapy (ECT) and algorithm-ba... more To compare the effects of right unilateral (RUL) electroconvulsive therapy (ECT) and algorithm-based pharmacologic treatment (APT) on neurocognitive function in treatment-resistant bipolar disorder depression. Inpatients with DSM-IV-TR-diagnosed, treatment-resistant bipolar depression, who were acutely admitted to 1 of the 7 clinical study centers in Norway, were recruited from May 2008 to April 2011 into a prospective, randomized controlled, 6-week acute treatment trial. General neurocognitive function was assessed with the MATRICS Consensus Cognitive Battery (MCCB), and retrograde memory for autobiographical events was assessed with the Autobiographical Memory Interview-Short Form (AMI-SF) before and shortly after (mean = 23.5 days) a trial with either RUL brief-pulse ECT (mean dose = 233.3 mC) or APT. Seventy-three patients entered, and 39 (nECT = 19, nAPT = 20) completed. Both groups showed improvements in all MCCB domain scores, with no significant differences between the study...
Objective. To explore the effect of ever having tried to conceive for more than 12 months on leve... more Objective. To explore the effect of ever having tried to conceive for more than 12 months on levels of anxiety and depressive symptoms, and to investigate if symptom levels of anxiety and depression in infertile women who remain childless, or go on to have children, respectively, differ from symptom levels in mothers without reports of infertility. Methods. Analyses were based information from 12,584 Norwegian women aged 19-45 who participated in the North-Trøndelag Health Study 1995-97 and data from the Medical Birth Registry of Norway. Anxiety and depressive symptoms were measured by the Hospital Anxiety and Depression Scale. Results. Having tried to conceive for more than 12 months (ever) was weakly associated with higher levels of depressive symptoms. In the categorical analyses, women with resolved infertility had higher levels of anxiety symptoms (B=0.25 (95% CI=0.04; 0.47)), and voluntarily childfree had lower levels of depressive symptoms (B=-0.05 (95% CI=-0.50; -0.21)), than mothers without infertility. However, women with current primary or current secondary infertility had levels of anxiety and depression not significantly different from mothers without infertility. Conclusion. At the population level, and taking a longitudinal perspective, unresolved infertility is less burdensome than findings from studies on women seeking help for infertility suggest.
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Papers by Ute Kessler
Methods. Analyses were based information from 12,584 Norwegian women aged 19-45 who participated in the North-Trøndelag Health Study 1995-97 and data from the Medical Birth Registry of Norway. Anxiety and depressive symptoms were measured by the Hospital Anxiety and Depression Scale.
Results. Having tried to conceive for more than 12 months (ever) was weakly associated with higher levels of depressive symptoms. In the categorical analyses, women with resolved infertility had higher levels of anxiety symptoms (B=0.25 (95% CI=0.04; 0.47)), and voluntarily childfree had lower levels of depressive symptoms (B=-0.05 (95% CI=-0.50; -0.21)), than mothers without infertility. However, women with current primary or current secondary infertility had levels of anxiety and depression not significantly different from mothers without infertility.
Conclusion. At the population level, and taking a longitudinal perspective, unresolved infertility is less burdensome than findings from studies on women seeking help for infertility suggest.
Methods. Analyses were based information from 12,584 Norwegian women aged 19-45 who participated in the North-Trøndelag Health Study 1995-97 and data from the Medical Birth Registry of Norway. Anxiety and depressive symptoms were measured by the Hospital Anxiety and Depression Scale.
Results. Having tried to conceive for more than 12 months (ever) was weakly associated with higher levels of depressive symptoms. In the categorical analyses, women with resolved infertility had higher levels of anxiety symptoms (B=0.25 (95% CI=0.04; 0.47)), and voluntarily childfree had lower levels of depressive symptoms (B=-0.05 (95% CI=-0.50; -0.21)), than mothers without infertility. However, women with current primary or current secondary infertility had levels of anxiety and depression not significantly different from mothers without infertility.
Conclusion. At the population level, and taking a longitudinal perspective, unresolved infertility is less burdensome than findings from studies on women seeking help for infertility suggest.