Secure Bioinformatics and Genomics Cloud, Software and Services
Accelerate your research with intuitive solutions that provide rapid insight and powerful visualizations.
Genomics & bioinformatics expertise built-in
- AI-assisted user interface
- Intuitive visualizations
- Custom analyses
Servers and UNIX unnecessary
- Secure, reliable & accurate
- BLAST, SRA BLAST, Genome Browsers
- On-demand scaling
Designed for Collaboration
- Centralized data store
- Analysis sharing & annotation
- History & audit trails
Genomics data is key to understanding diseases, designing new drugs, ensure food quality and security, measuring and protecting the environment. SequenceServer empowers researchers with data-driven insights. It's used in hundreds of companies and labs. We've been cited 250 times. We want to also help you to make bold impactful discoveries.
SequenceServer is the best tool for BLASTing standard and custom genomes and transcriptomes. No queues or unreasonable limitations. It's also great for BLASTing SRA, getting gene annotations, infering gene function, browsing genomes, and for sharing and annotating data and results with your team, students, or community.
Organizations worldwide use SequenceServer
Benefits of using SequenceServer Cloud
Just do the research
Focus on the science, not UNIX, servers, updates or waiting for NCBI.
Simply upload FASTA files or select standard sequence databases. Begin BLASTing within seconds. 250 citations can't be wrong. Focus on the biology.
Powerful visualizations
Gain deep insight through diverse visualization approaches.
All BLAST results include pairwise alignment graphs, Circos-style overview plots, and length distribution histograms. These plots clarify and help to interpret analysis results. Publication-ready export in .PNG or .SVG formats. You work faster and more accurately.
Intelligent user interface
Faster & more accurate.
Our user interface elegantly aims to make you happy. "AI" detection of nucleotides vs amino-acids. Automagic FASTQ to FASTA conversion. Automagic selection of the best BLAST method.
Such features accelerate your workflow and reduce your chances of making errors.
Share and collaborate
Have a central SequenceServer database for your team.
Share databases and analyses with colleagues. Foster collaboration and knowledge-sharing within your team. Annotate and comment on BLAST analyses (like in Acrobat). Share result with peers to leverage their expertise.
Export data in various formats
Streamline your R&D by integrating with other tools.
Download BLAST reports as HTML, XML or tab-delimited text. Programmatically submit and retrieve remote BLAST searches using python or command-line API. Import results into R or python. Export FASTA hit sequences or pairwise alignments. Link out to NCBI, Uniprot, jBrowse, IGV, or custom databases.
Custom links and design
Customize your SequenceServer and integrate it with other resources.
Add links from search hits to custom genome browsers or domain-specific databases. Integrate SequenceServer with other parts of your lab or community website. Change fonts, colors, and logos.
Don't melt your laptop!
SequenceServer Cloud supports intense and long-running queries.
SequenceServer Cloud is high-performance, high-availability, and scalable BLAST platform. It won't overheat (unlike your laptop!). Your BLAST search starts instantly. We intelligently leverage cloud computing to support large queries. Keep your laptop for lap-top-work.
Support your students
Intuitive BLAST analysis for large student cohorts.
No more waiting at the NCBI website. We leverage cloud computing to instantly start your BLAST search. SequenceServer intelligently scales to access (almost) infinite cloud resources. Hundreds of students can run BLAST seraches simultaneously. Perfect for teaching labs with large class sizes. Our intuitive user interface and visualizations flatten learning curves. Monitor student engagement with detailed logging.
Robust, Secure and private
Secured to the higest standards.
We prioritize your data's security and privacy. With advanced SSL/TLS encryption, proactive firewalls, intrusion detection, and exclusive Virtual Private Clouds (VPCs), we safeguard your data to the highest industry standards. Control access with popular Single-Sign-On (SSO) providers and track interactions with detailed audit trail logs. Trusted by academics, biotech, pharma, and agro-industry users worldwide, we're committed to protecting your data as if it were our own.
Use Cases
Comparative Genomics
Compare genomes across multiple species, identify conserved regions, protein domains, homologous genes, copy number differences, sequence differences, species, and evolutionary relationships. Deepen our understanding of the genetic basis of various biological traits and functions, and evolutionary histories.
Gene Curation and Annotation
Validate and refine gene predictions using SequenceServer BLAST searches against known gene sequences and protein domains. Identify potential inaccuracies in gene annotations and improve the qualities of genesets and genome assemblies.
Visual Analyses
Make graphs for visualizing and publishing. Get a range of BLAST plots, such as summary statistics, pairwise alignments and hit length distributions. Explore SRA read alignments, SNPs and INDELs with the IGV genome browser. Make and scrutinize gene and protein domain annotations with DNA Visualizer.
Design Diagnostic Markers
SequenceServer helps identify unique sequence regions in viruses, bacteria or other target organisms that can serve as diagnostic markers for disease detection. Design PCR or qPCR primers and probes, or specific guide RNA oligos (gRNA) for CRISPR/Cas9 assays. Improving the specificity and sensitivity of molecular-genomic approaches supports disease surveillance and management efforts.
Functional Characterization
Identify and analyze novel genes of interest in non-model organisms, as well as newly sequenced or understudied genomes. By comparing these sequences to known genes in other organisms, researchers can gain insights into the potential functional domains and biological roles of the newly discovered genes, guiding further experimental validation and functional studies.
Variant Calling Analysis
Explore DNA/RNA sequencing data from the NCBI Short Read Archive. Build SNP marker arrays for agricultural breeding. Identify and distinguish genetic variants in sequence data from wild species. Perform genome-wide mapping. Output alignment results for downstream analyses.
Data Hosting and Genome Browsers
Do you want to share genomes and annotations for your favourite species publicly or privately? SequenceServer makes sharing with others in your team or the wider community easy. Explore your data together with comments and genome browsers. Make your data have more impact.
Peer-reviewed citations to our publication
The 2019 MBE paper in which we published SequenceServer is cited almost weekly, with more than 200 citations.
Check Google Scholar for the latest, or a slightly dated list here.
Always Open Source
We take pride in keeping our core open source and free for all. Explore our documentation, connect with us on our community support forum, or contribute to the GitHub repository. Together, we're advancing bioinformatics one BLAST at a time.
Ready to Revolutionize Your Sequence Analysis?
Get started with SequenceServer today
Try our Cloud ServiceLatest Updates
New blog post: Interpreting BLASTN nucleotide BLAST results
2024-05
New blog post: Taxonomic restriction of BLAST searches
2024-05
New blog post: DNA feature exploration with the DNA Visualizer SequenceServer tool
2024-05
New blog post: Generating guide RNAs and sequencing primers for CRISPR knockouts
2024-05
New blog post: Search Raw Reads from NCBI's SRA Database 🧬
2024-03