Exciting news from our portfolio company BOOST Pharma, which has announced positive top-line clinical data from the Phase I/II BOOSTB4 study. BOOST Pharma is developing a novel therapy for Osteogenesis Imperfecta (OI), a rare genetic disease, and the results are truly promising. The study demonstrated that the therapy is both safe and well tolerated in both prenatal and postnatal administration, and most impressively, it showed a 75% reduction in bone fracture rate – a central endpoint for patients and regulators alike. This is a significant breakthrough in the treatment of OI and sets BOOST Pharma’s therapy apart from anything else currently in development. “This is the first and only treatment that can be given directly before and after birth, and that has shown such a large reduction in fracture rate. Fracture rate is the endpoint which really matters for patients as well as regulators. We look forward to the ongoing dialogues and seeing this treatment reach patients worldwide,” says Jonathan Ilicki, Board Director at BOOST Pharma and Principal at Industrifonden. A huge congratulations to the BOOST Pharma team for this remarkable achievement! We look forward to seeing your continued success as this therapy progresses. Read the full announcement below.
BOOST Pharma announces positive Phase I/II study results, demonstrating over 75% reduction of fracture rate in children born with rare bone disease Osteogenesis Imperfecta (OI).