This review assesses the extent and the significance of catalytic versatility shown by several
inositol phosphate kinases: the inositol phosphate multikinase, the reversible Ins(1,3,4)P 3 /…

This review assesses the authenticity of inositol hexakisphosphate (InsP 6 ) being a wide-ranging
regulator of many important cellular functions. Against a background in which the …

Growing evidence suggests that phosphoinositides play an important role in membrane
traffic. A polyphosphoinositide phosphatase, synaptojanin 1, was identified as a major …

… In some experiments, particularly when a new HPLC column was installed, the percentage
of B at 10 min was increased to 50%. This change in the gradient, plus the tendency of …

The inositol pyrophosphates (PP-InsPs) are a specialized group of “energetic” signaling
molecules found in yeasts, plants and animals. PP-InsPs boast the most crowded three …

A central feature of Salmonella pathogenicity is the bacterium's ability to enter into non‐phagocytic
cells. Bacterial internalization is the consequence of cellular responses characterized …

Inositol pyrophosphates are small, diffusible signaling molecules that possess the most
concentrated three‐dimensional array of phosphate groups in Nature; up to eight phosphates …

Diphosphoinositol pentakisphosphate (PP‐InsP 5 or ‘InsP 7’) and bisdiphosphoinositol
tetrakisphosphate ([PP] 2‐InsP 4 or ‘InsP 8’) are the most highly phosphorylated members of the …

… Proteins were eluted with a gradient generated by mixing buffer A with buffer B (buffer A
plus 1m KCl): 0–10 min, 0% buffer B; 10–20 min, 15–85% B; 20–30 min, 100% B. The InsP 6 …

Cells from across the phylogenetic spectrum contain a variety of inositol phosphates. Many
different functions have been ascribed to this group of compounds. However, it is remarkable …