User profiles for Michael A. Gilchrist
Michael A. GilchristAssociate Professor, University of Tennessee, Knoxville Verified email at utk.edu Cited by 2256 |
Modeling host–parasite coevolution: a nested approach based on mechanistic models
MA Gilchrist, A Sasaki - Journal of Theoretical Biology, 2002 - Elsevier
In this study we introduce a mechanistic framework for modeling host–parasite coevolution
using a nested modeling approach. The first step in this approach is to construct a …
using a nested modeling approach. The first step in this approach is to construct a …
The creation of three-dimensional finite element models for simulating head impact biomechanics
TJ Horgan, MD Gilchrist - International Journal of Crashworthiness, 2003 - Springer
A new 3 dimensional finite element representation of the human head complex has been
constructed for simulating the transient occurrences of simple pedestrian accidents. This paper …
constructed for simulating the transient occurrences of simple pedestrian accidents. This paper …
Evolution of virulence: interdependence, constraints, and selection using nested models
MA Gilchrist, D Coombs - Theoretical population biology, 2006 - Elsevier
Natural selection acts on virus populations at two distinct but interrelated levels: within
individual hosts and between them. Studies of the evolution of virulence typically focus on …
individual hosts and between them. Studies of the evolution of virulence typically focus on …
An age-structured model of HIV infection that allows for variations in the production rate of viral particles and the death rate of productively infected cells
Mathematical models of HIV-1 infection can help interpret drug treatment experiments and
improve our understanding of the interplay between HIV-1 and the immune system. We …
improve our understanding of the interplay between HIV-1 and the immune system. We …
Designing the energy absorption capacity of functionally graded foam materials
L Cui, S Kiernan, MD Gilchrist - Materials Science and Engineering: A, 2009 - Elsevier
In this paper, a functionally graded foam model is proposed in order to improve the energy
absorption characteristics offered by uniform foams. In this novel model, the characteristics of …
absorption characteristics offered by uniform foams. In this novel model, the characteristics of …
A model of protein translation including codon bias, nonsense errors, and ribosome recycling
MA Gilchrist, A Wagner - Journal of theoretical biology, 2006 - Elsevier
We present and analyse a model of protein translation at the scale of an individual messenger
RNA (mRNA) transcript. The model we develop is unique in that it incorporates the …
RNA (mRNA) transcript. The model we develop is unique in that it incorporates the …
The Genome of the Western Clawed Frog Xenopus tropicalis
U Hellsten, RM Harland, MJ Gilchrist, D Hendrix… - Science, 2010 - science.org
The western clawed frog Xenopus tropicalis is an important model for vertebrate development
that combines experimental advantages of the African clawed frog Xenopus laevis with …
that combines experimental advantages of the African clawed frog Xenopus laevis with …
Characterization of the anisotropic mechanical properties of excised human skin
The mechanical properties of skin are important for a number of applications including
surgery, dermatology, impact biomechanics and forensic science. In this study, we have …
surgery, dermatology, impact biomechanics and forensic science. In this study, we have …
Influence of FE model variability in predicting brain motion and intracranial pressure changes in head impact simulations
TJ Horgan, MD Gilchrist - International Journal of Crashworthiness, 2004 - Taylor & Francis
In order to create a useful computational tool that will aid in the understanding and perhaps
prevention of head injury, it is important to know the quantitative influence of the constitutive …
prevention of head injury, it is important to know the quantitative influence of the constitutive …
Optimizing within-host viral fitness: infected cell lifespan and virion production rate
We explore how an infected cell's virion production rate can affect the relative fitness of a virus
within a host. We perform an invasion analysis, based on an age-structured model of viral …
within a host. We perform an invasion analysis, based on an age-structured model of viral …