Background: A large yet heterogeneous body of literature exists suggesting that endothelial
dysfunction appears early in type 1 diabetes, due to hyperglycemia-induced oxidative stress. …

Objectives Ever since the first research on barriers to physical activity (PA) highlighting fear
of hypoglycemia as a major barrier, many studies have attempted to understand their …

During exercise in hypoxia, O 2 delivery to brain and muscle is compromised, and oxidative
stress is elicited. Cocoa flavanols (CF) have antioxidant capacities and can increase blood …

Background Ultra-trail running races pose appreciable physiological challenges, particularly
for glucose metabolism. Previous studies that yielded divergent results only measured …

To the Editor: In recent years, there has been an increased interest in precision medicine in
order to provide treatment and disease management that takes into account individual …

OBJECTIVE In type 1 diabetes, autonomic dysfunction may occur early as a decrease in
heart rate variability (HRV). In populations without diabetes, the positive effects of exercise …

Aim From an early age, exercise is key to managing type 1 diabetes (T1D). However,
hypoglycemia around aerobic exercise is a major barrier to physical activity in children. We explore …

Aims/hypothesis Early compromised endothelial function challenges the ability of
individuals with type 1 diabetes to perform normal physical exercise. The exact mechanisms …

Background: Type 2 diabetes mellitus (T2DM) is associated with a high risk of vascular
complications. Interestingly, cocoa flavanols (CF) can exert beneficial vascular effects in non-…

1 Face au vieillissement de la population française, la prévention de la perte d’autonomie est
au cœur des préoccupations de santé, notamment via l’activité physique adaptée (APA) et l…