Dopaminergic network differences in human impulsivity
Dopamine (DA) has long been implicated in impulsivity, but the precise mechanisms linking
human variability in DA signaling to differences in impulsive traits remain largely unknown …
human variability in DA signaling to differences in impulsive traits remain largely unknown …
Mesolimbic dopamine reward system hypersensitivity in individuals with psychopathic traits
Psychopathy is a personality disorder that is strongly linked to criminal behavior. Using [18F]
fallypride positron emission tomography and blood oxygen level–dependent functional …
fallypride positron emission tomography and blood oxygen level–dependent functional …
Midbrain dopamine receptor availability is inversely associated with novelty-seeking traits in humans
Novelty-seeking personality traits are a major risk factor for the development of drug abuse
and other unsafe behaviors. Rodent models of temperament indicate that high novelty …
and other unsafe behaviors. Rodent models of temperament indicate that high novelty …
Combination therapy with nusinersen and onasemnogene abeparvovec-xioi in spinal muscular atrophy type I
A Mirea, ES Shelby, M Axente, M Badina… - Journal of clinical …, 2021 - mdpi.com
Background: Spinal muscular atrophy (SMA) is a neuromuscular progressive disease,
characterized by decreased amounts of survival motor neuron (SMN) protein, due to an …
characterized by decreased amounts of survival motor neuron (SMN) protein, due to an …
Risk of death in comorbidity subgroups of hospitalized COVID-19 patients inferred by routine laboratory markers of systemic inflammation on admission: a …
Our study objective was to construct models using 20 routine laboratory parameters on
admission to predict disease severity and mortality risk in a group of 254 hospitalized COVID …
admission to predict disease severity and mortality risk in a group of 254 hospitalized COVID …
[HTML][HTML] Physical therapy and nusinersen impact on spinal muscular atrophy rehabilitative outcome
A Mirea, MC Leanca, G Onose, C Sporea… - Frontiers in Bioscience …, 2022 - imrpress.com
Introduction: Spinal muscular atrophy (SMA) is a progressive neurological disease with
autosomal recessive transmission that affects motor neurons, causing their loss and …
autosomal recessive transmission that affects motor neurons, causing their loss and …
Evaluation of prognostic significance of hematological profiles after the intensive phase treatment in pulmonary tuberculosis patients from Romania
We evaluated in this cohort study the predictive ability of 23 peripheral blood parameters
and ratios for treatment outcomes after the 2-month intensive phase in patients with PTB. In …
and ratios for treatment outcomes after the 2-month intensive phase in patients with PTB. In …
Prediction of treatment outcome with inflammatory biomarkers after 2 months of therapy in pulmonary tuberculosis patients: Preliminary results
S Stefanescu, R Cocoș, A Turcu-Stiolica, ES Shelby… - Pathogens, 2021 - mdpi.com
Pro-inflammatory mediators play an important role in the pathogenesis of pulmonary
tuberculosis. Consecutively, 26 pulmonary tuberculosis patients were enrolled in our study …
tuberculosis. Consecutively, 26 pulmonary tuberculosis patients were enrolled in our study …
[HTML][HTML] Clinical features and genetics in non-5q spinal muscular atrophy caused by acid ceramidase deficiency
M Axente, ES Shelby, A Mirea, C Sporea… - Journal of Medicine …, 2021 - ncbi.nlm.nih.gov
Spinal muscular atrophy (SMA) is a spectrum of genetically and clinically heterogeneous
diseases leading to the progressive degeneration of peripheric motor neurons with …
diseases leading to the progressive degeneration of peripheric motor neurons with …
Changes in pNFH Levels in Cerebrospinal Fluid and Motor Evolution after the Loading Dose with Nusinersen in Different Types of Spinal Muscular Atrophy
Aim and Objectives: The objective of our retrospective study was to investigate the changes
in pNFH levels in cerebrospinal fluid, which is a reliable marker of neuronal damage, after …
in pNFH levels in cerebrospinal fluid, which is a reliable marker of neuronal damage, after …