Dopaminergic network differences in human impulsivity

JW Buckholtz, MT Treadway, RL Cowan… - Science, 2010 - science.org
Dopamine (DA) has long been implicated in impulsivity, but the precise mechanisms linking
human variability in DA signaling to differences in impulsive traits remain largely unknown …

Mesolimbic dopamine reward system hypersensitivity in individuals with psychopathic traits

JW Buckholtz, MT Treadway, RL Cowan… - Nature …, 2010 - nature.com
Psychopathy is a personality disorder that is strongly linked to criminal behavior. Using [18F]
fallypride positron emission tomography and blood oxygen level–dependent functional …

Midbrain dopamine receptor availability is inversely associated with novelty-seeking traits in humans

DH Zald, RL Cowan, P Riccardi… - Journal of …, 2008 - Soc Neuroscience
Novelty-seeking personality traits are a major risk factor for the development of drug abuse
and other unsafe behaviors. Rodent models of temperament indicate that high novelty …

Combination therapy with nusinersen and onasemnogene abeparvovec-xioi in spinal muscular atrophy type I

A Mirea, ES Shelby, M Axente, M Badina… - Journal of clinical …, 2021 - mdpi.com
Background: Spinal muscular atrophy (SMA) is a neuromuscular progressive disease,
characterized by decreased amounts of survival motor neuron (SMN) protein, due to an …

Risk of death in comorbidity subgroups of hospitalized COVID-19 patients inferred by routine laboratory markers of systemic inflammation on admission: a …

R Cocoş, B Mahler, A Turcu-Stiolica, A Stoichiță… - Viruses, 2022 - mdpi.com
Our study objective was to construct models using 20 routine laboratory parameters on
admission to predict disease severity and mortality risk in a group of 254 hospitalized COVID …

[HTML][HTML] Physical therapy and nusinersen impact on spinal muscular atrophy rehabilitative outcome

A Mirea, MC Leanca, G Onose, C Sporea… - Frontiers in Bioscience …, 2022 - imrpress.com
Introduction: Spinal muscular atrophy (SMA) is a progressive neurological disease with
autosomal recessive transmission that affects motor neurons, causing their loss and …

Evaluation of prognostic significance of hematological profiles after the intensive phase treatment in pulmonary tuberculosis patients from Romania

S Ştefanescu, R Cocoş, A Turcu-Stiolica, B Mahler… - PLoS …, 2021 - journals.plos.org
We evaluated in this cohort study the predictive ability of 23 peripheral blood parameters
and ratios for treatment outcomes after the 2-month intensive phase in patients with PTB. In …

Prediction of treatment outcome with inflammatory biomarkers after 2 months of therapy in pulmonary tuberculosis patients: Preliminary results

S Stefanescu, R Cocoș, A Turcu-Stiolica, ES Shelby… - Pathogens, 2021 - mdpi.com
Pro-inflammatory mediators play an important role in the pathogenesis of pulmonary
tuberculosis. Consecutively, 26 pulmonary tuberculosis patients were enrolled in our study …

[HTML][HTML] Clinical features and genetics in non-5q spinal muscular atrophy caused by acid ceramidase deficiency

M Axente, ES Shelby, A Mirea, C Sporea… - Journal of Medicine …, 2021 - ncbi.nlm.nih.gov
Spinal muscular atrophy (SMA) is a spectrum of genetically and clinically heterogeneous
diseases leading to the progressive degeneration of peripheric motor neurons with …

Changes in pNFH Levels in Cerebrospinal Fluid and Motor Evolution after the Loading Dose with Nusinersen in Different Types of Spinal Muscular Atrophy

M Badina, GC Bejan, C Sporea, L Padure, A Mirea… - Medicina, 2023 - mdpi.com
Aim and Objectives: The objective of our retrospective study was to investigate the changes
in pNFH levels in cerebrospinal fluid, which is a reliable marker of neuronal damage, after …