Mesolimbic dopamine signals the value of work

AA Hamid, JR Pettibone, OS Mabrouk, VL Hetrick… - Nature …, 2016 - nature.com
Dopamine cell firing can encode errors in reward prediction, providing a learning signal to
guide future behavior. Yet dopamine is also a key modulator of motivation, invigorating …

Cortical cholinergic signaling controls the detection of cues

HJ Gritton, WM Howe, CS Mallory… - Proceedings of the …, 2016 - National Acad Sciences
The cortical cholinergic input system has been described as a neuromodulator system that
influences broadly defined behavioral and brain states. The discovery of phasic, trial-based …

Acetylcholine release in prefrontal cortex promotes gamma oscillations and theta–gamma coupling during cue detection

WM Howe, HJ Gritton, NA Lusk, EA Roberts… - Journal of …, 2017 - Soc Neuroscience
The capacity for using external cues to guide behavior (“cue detection”) constitutes an
essential aspect of attention and goal-directed behavior. The cortical cholinergic input …

Functional clustering algorithm for the analysis of dynamic network data

S Feldt, J Waddell, VL Hetrick, JD Berke… - Physical Review E …, 2009 - APS
We formulate a technique for the detection of functional clusters in discrete event data. The
advantage of this algorithm is that no prior knowledge of the number of functional groups is …

Sea of electrodes array (SEA): extremely dense and high-count silicon-based electrode array technology for high-resolution high-bandwidth interfacing with 3D neural …

AS Zardini, B Rostami, K Najafi, VL Hetrick, OJ Ahmed - Biorxiv, 2021 - biorxiv.org
In this work, we propose a new silicon-based micro-fabrication technology to fabricate 3D
high-density high-electrode-count neural micro-probe arrays scalable to thousands and …

A pragmatic and successful approach to treating nonsmall-cell lung carcinoma

PD Kiernan, PR Graling, VL Hetrick, BE Vaughan… - AORN journal, 2004 - Elsevier
LUNG CANCER is the single leading cause of cancer deaths for men and women
combined. Nonsmall-cell lung carcinoma (NSCLC), which results largely from smoking …

Bilateral lung volume reduction surgery

PR Graling, VL Hetrick, PD Kiernan - AORN journal, 1996 - Wiley Online Library
ABSTRACT A new surgical approach, bilateral lung volume reduction surgery (LVRS), offers
hope for select patients with chronic pulmonary emphysema (CPE). Bilateral LVRS …

Memory formation: from network structure to neural dynamics

S Feldt, JX Wang, VL Hetrick… - … Transactions of the …, 2010 - royalsocietypublishing.org
Understanding the neural correlates of brain function is an extremely challenging task, since
any cognitive process is distributed over a complex and evolving network of neurons that …

Managing the patient with perforated intrathoracic esophagus

PR Graling, VL Hetrick, B Vaughan… - AORN journal, 1998 - Wiley Online Library
The thoracic perioperative specialty team members at Inova Fairfax Hospital, Falls Church,
Va, designed guidelines to improve the management of patients with esophageal …

Optogenetically-evoked cortical cholinergic transients in mice expressing channelrhodopsin-2 (ChR2) in cholinergic neurons.

H Gritton, W Howe, V Hetrick, G Paolone… - Society for …, 2010 - iris.univr.it
The use of enzyme-selective microelectrodes for the real-time amperometric detection of
neurotransmitter release has generated new insights in the regulation and function of major …