Palmieri B, Tremblay JP, Lodi D. Past, present and future of myoblast transplantation in the
treatment of Duchenne muscular dystrophy. Pediatr Transplantation 2010: 14: 813–819.© …

Introduction: Myopathies produce deficits in skeletal muscle function and, in some cases,
literally progressive loss of skeletal muscles. The transplantation of cells able to differentiate …

Background Duchenne muscular dystrophy (DMD) is the most common inherited muscle
disease, leading to severe disability and death in young men. Death is caused by the …

Initial cell transplantation trials dedicated to the repair of striated muscles in muscular
dystrophies produced mitigated results and underlined some limitations of cellular …

Myopathies produce deficits in skeletal muscle function and, in some cases, progressive and
irreversible loss of skeletal muscles. The transplantation of myogenic cells, that is, cells able …

Duchenne muscular dystrophy (DMD) is a genetic X-linked recessive orphan disease that
affects approximately 1 in 3 500 male births. Boys with DMD have progressive and …

The intramuscular transplantation of satellite cell–derived myoblasts is a potential strategy to
treat skeletal muscle pathologies. If developed properly, clinical benefits could be expected …

Duchenne muscular dystrophy is a fatal, genetic disorder in which dystrophin-deficient
muscle progressively degenerates, for which dystrophin gene transfer could provide …

Currently a multiplicity of experimental approaches to therapy for genetic muscle diseases is
being investigated. These include replacement of the missing gene, manipulation of the …

Muscle injury can result from insults that range from mechanical overloading, traumatic
injury, metabolic disorders, ischemic events, and congenital dysfunction. Often these insults …