Harnessing human microbiomes for disease prediction
The human microbiome has been increasingly recognized as having potential use for
disease prediction. Predicting the risk, progression, and severity of diseases holds promise …
disease prediction. Predicting the risk, progression, and severity of diseases holds promise …
Prognostic biomarkers based on proteomic technology in COPD: a recent review
H Fang, Y Liu, Q Yang, S Han… - International Journal of …, 2023 - Taylor & Francis
Chronic obstructive pulmonary disease (COPD) is a common heterogeneous respiratory
disease which is characterized by persistent and incompletely reversible airflow limitation …
disease which is characterized by persistent and incompletely reversible airflow limitation …
Lower Airway Dysbiosis Augments Lung Inflammatory Injury in Mild-to-Moderate Chronic Obstructive Pulmonary Disease
Rationale: Chronic obstructive pulmonary disease (COPD) is associated with high morbidity,
mortality, and healthcare costs. Cigarette smoke is a causative factor; however, not all heavy …
mortality, and healthcare costs. Cigarette smoke is a causative factor; however, not all heavy …
[HTML][HTML] The application of multi-omics in the respiratory microbiome: Progresses, challenges and promises
The study of the respiratory microbiome has entered a multi-omic era. Through integrating
different omic data types such as metagenome, metatranscriptome, metaproteome …
different omic data types such as metagenome, metatranscriptome, metaproteome …
Human genetic associations of the airway microbiome in chronic obstructive pulmonary disease
J Gao, Y Yang, X Xiang, H Zheng, X Yi, F Wang… - Respiratory …, 2024 - Springer
Little is known about the relationships between human genetics and the airway microbiome.
Deeply sequenced airway metagenomics, by simultaneously characterizing the microbiome …
Deeply sequenced airway metagenomics, by simultaneously characterizing the microbiome …
The relevance of eosinophils in chronic obstructive pulmonary disease: inflammation, microbiome, and clinical outcomes
A Higham, A Beech, D Singh - Journal of Leukocyte Biology, 2024 - academic.oup.com
Chronic obstructive pulmonary disease is caused by the inhalation of noxious particles such
as cigarette smoke. The pathophysiological features include airway inflammation, alveolar …
as cigarette smoke. The pathophysiological features include airway inflammation, alveolar …
[HTML][HTML] Correcting dysbiosis in the lungs of COPD, one pathogen at a time
KK Wong, LN Segal - Cell Host & Microbe, 2023 - Elsevier
In this issue of Cell Host & Microbe, Liang et al. demonstrate through genomic analysis of
the sputum microbiome from COPD patients and preclinical models that Staphylococcus …
the sputum microbiome from COPD patients and preclinical models that Staphylococcus …
Design of probiotic delivery systems and their therapeutic effects on targeted tissues
C Xu, J Guo, B Chang, Y Zhang, Z Tan, Z Tian… - Journal of Controlled …, 2024 - Elsevier
The microbiota at different sites in the body is closely related to disease. The intake of
probiotics is an effective strategy to alleviate diseases and be adjuvant in their treatment …
probiotics is an effective strategy to alleviate diseases and be adjuvant in their treatment …
The translational potential of the lung microbiome as a biomarker and a therapeutic target for chronic obstructive pulmonary disease
Chronic obstructive pulmonary disease (COPD) is a major chronic lung disease with a
leading global morbidity and mortality. Emerging evidence suggests that the lung …
leading global morbidity and mortality. Emerging evidence suggests that the lung …
The Lung Microbiome
JH Lipinksi, P Ranjan, RP Dickson… - The Journal of …, 2024 - journals.aai.org
Although the lungs were once considered a sterile environment, advances in sequencing
technology have revealed dynamic, low-biomass communities in the respiratory tract, even …
technology have revealed dynamic, low-biomass communities in the respiratory tract, even …