The dynamic lung microbiome in health and disease
JG Natalini, S Singh, LN Segal - Nature Reviews Microbiology, 2023 - nature.com
New methods and technologies within the field of lung biology are beginning to shed new
light into the microbial world of the respiratory tract. Long considered to be a sterile …
light into the microbial world of the respiratory tract. Long considered to be a sterile …
Blood eosinophils and chronic obstructive pulmonary disease: a global initiative for chronic obstructive lung disease science committee 2022 review
D Singh, A Agusti, FJ Martinez, A Papi… - American journal of …, 2022 - atsjournals.org
The Global Initiative for Chronic Obstructive Lung Disease (GOLD) published its first report
for the diagnosis and management of chronic obstructive pulmonary disease (COPD) in …
for the diagnosis and management of chronic obstructive pulmonary disease (COPD) in …
Multi-omics analyses of airway host–microbe interactions in chronic obstructive pulmonary disease identify potential therapeutic interventions
Z Yan, B Chen, Y Yang, X Yi, M Wei… - Nature …, 2022 - nature.com
The mechanistic role of the airway microbiome in chronic obstructive pulmonary disease
(COPD) remains largely unexplored. We present a landscape of airway microbe–host …
(COPD) remains largely unexplored. We present a landscape of airway microbe–host …
Lung microbiome: new insights into the pathogenesis of respiratory diseases
The lungs were long thought to be sterile until technical advances uncovered the presence
of the lung microbial community. The microbiome of healthy lungs is mainly derived from the …
of the lung microbial community. The microbiome of healthy lungs is mainly derived from the …
Airway dysbiosis accelerates lung function decline in chronic obstructive pulmonary disease
W Liang, Y Yang, S Gong, M Wei, Y Ma, R Feng… - Cell host & …, 2023 - cell.com
Progressive lung function decline is a hallmark of chronic obstructive pulmonary disease
(COPD). Airway dysbiosis occurs in COPD, but whether it contributes to disease progression …
(COPD). Airway dysbiosis occurs in COPD, but whether it contributes to disease progression …
Treatment trials in young patients with chronic obstructive pulmonary disease and pre–chronic obstructive pulmonary disease patients: time to move forward
Chronic obstructive pulmonary disease (COPD) is the end result of a series of dynamic and
cumulative gene–environment interactions over a lifetime. The evolving understanding of …
cumulative gene–environment interactions over a lifetime. The evolving understanding of …
The airway microbiome mediates the interaction between environmental exposure and respiratory health in humans
L Lin, X Yi, H Liu, R Meng, S Li, X Liu, J Yang, Y Xu… - Nature Medicine, 2023 - nature.com
Exposure to environmental pollution influences respiratory health. The role of the airway
microbial ecosystem underlying the interaction of exposure and respiratory health remains …
microbial ecosystem underlying the interaction of exposure and respiratory health remains …
Pathological mechanism and targeted drugs of COPD
P Guo, R Li, TH Piao, CL Wang, XL Wu… - International journal of …, 2022 - Taylor & Francis
Chronic obstructive pulmonary disease (COPD) includes chronic bronchitis, emphysema,
and small airway obstruction. Incompletely reversible airflow limitation, inflammation …
and small airway obstruction. Incompletely reversible airflow limitation, inflammation …
Therapeutic targeting of the respiratory microbiome
SH Chotirmall, D Bogaert, JD Chalmers… - American journal of …, 2022 - atsjournals.org
Culture-independent microbiology has transformed our understanding of the respiratory
microbiome in health and disease (1). Enabled by advances in next-generation sequencing …
microbiome in health and disease (1). Enabled by advances in next-generation sequencing …
The microbiome: an integral player in immune homeostasis and inflammation in the respiratory tract
The last decade of microbiome research has highlighted its fundamental role in systemic
immune and metabolic homeostasis. The microbiome plays a prominent role during …
immune and metabolic homeostasis. The microbiome plays a prominent role during …